Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Victoria A. McGuire"'
Autor:
Nadège Poncet, Fiona E Mitchell, Adel F M Ibrahim, Victoria A McGuire, Grant English, J Simon C Arthur, Yun-Bo Shi, Peter M Taylor
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89547 (2014)
The System L1-type amino acid transporter mediates transport of large neutral amino acids (LNAA) in many mammalian cell-types. LNAA such as leucine are required for full activation of the mTOR-S6K signalling pathway promoting protein synthesis and ce
Externí odkaz:
https://doaj.org/article/faf64e31f1d8416fabeefd8b6f377ac6
Publikováno v:
Photochemistry and photobiologyReferences. 97(2)
Photoageing and skin cancer are major causes of morbidity and are a high cost to society. Interest in the development of photoprotective agents for inclusion in topical cosmetic and sunscreen products is profound. Recently, amino acids with a sulfini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9abea43b8b93a91ade32c9514ed0f02
https://pubmed.ncbi.nlm.nih.gov/32959397
https://pubmed.ncbi.nlm.nih.gov/32959397
Publikováno v:
The Journal of investigative dermatology. 140(11)
UVR exposure is a widely applied technique in clinical and preclinical studies. Such experimental conditions provide crucial information on the biological responses of skin and cell models, which may then be extrapolated and interpreted, for example,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57b026c409de684cfebf97d8ab7c2ba
https://pubmed.ncbi.nlm.nih.gov/33099396
https://pubmed.ncbi.nlm.nih.gov/33099396
Autor:
Matthias Gaestel, J. Simon C. Arthur, Corinna Greger, Iain R. Phair, Pierre C McCarthy, Andrew R. Clark, Victoria A. McGuire, Katerina Pardali
Publikováno v:
Immunology and Cell Biology
IL‐33 is an IL‐1‐related cytokine that can act as an alarmin when released from necrotic cells. Once released, it can target various immune cells including mast cells, innate lymphoid cells and T cells to elicit a Th2‐like immune response. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa54fa5c8538c3424ad5cdade4bec2ec
https://doi.org/10.1111/imcb.12200
https://doi.org/10.1111/imcb.12200
Autor:
Ram K C Venigalla, Victoria A. McGuire, Laste Stojanovski, Rosemary G. Clarke, Rachel Toth, Janet C. Patterson-Kane, J. Simon C. Arthur, Ayaz Najafov, Frederick R. C. Simeons, Pierre C McCarthy
Publikováno v:
The EMBO Journal
Phosphoinositide-dependent kinase-1 (PDK1) controls the activation of a subset of AGC kinases. Using a conditional knockout of PDK1 in haematopoietic cells, we demonstrate that PDK1 is essential for B cell development. B-cell progenitors lacking PDK1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6fcd185d0b5786a6f98ae17371551d
https://doi.org/10.1038/emboj.2013.40
https://doi.org/10.1038/emboj.2013.40
Autor:
Victoria A. McGuire
Publikováno v:
The British journal of dermatology. 175(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed74135d8207b8dabd924e71b839b08b
https://pubmed.ncbi.nlm.nih.gov/27996121
https://pubmed.ncbi.nlm.nih.gov/27996121
Autor:
Jessica Schwermann, Ian H. Batty, Keunwook Lee, J. Crowe, J. S. C. Arthur, Victoria A. McGuire, S. J. O'Keefe, Alexander Gray, Susana G. Santos, Matthias Gaestel, Mark Boothby, Anna Aubareda, Natalia Ronkina, Jonathan L.E. Dean, Nicolas R. Leslie, Claire E. Monk
The stimulation of Toll-like receptors (TLRs) on macrophages by pathogen-associated molecular patterns (PAMPs) results in the activation of intracellular signaling pathways that are required for initiating a host immune response. Both phosphatidylino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3784d8346f368de4396036b8dfc7b9b
https://doi.org/10.1128/mcb.01691-12
https://doi.org/10.1128/mcb.01691-12
Autor:
Victoria A. McGuire, Robert S. Dawe
Publikováno v:
British Journal of Dermatology. 177:21-22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca54b9201ff06d2f4836de9878eb376
https://doi.org/10.1111/bjd.15614
https://doi.org/10.1111/bjd.15614
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology
Frontiers in Immunology
Pathogenic bacteria are detected by pattern-recognition receptors (PRRs) expressed on innate immune cells, which activate intracellular signal transduction pathways to elicit an immune response. Toll-like receptors are, perhaps, the most studied of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a41d2c8d03a4f6893fb5e7e65c357b51
http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00607/full
http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00607/full
Autor:
J. Simon C. Arthur, Shaista Naqvi, Alastair D. Reith, Mirjam W. M. Van Den Bosch, Suzanne E. Elcombe, Jonathan L.E. Dean, Victoria A. McGuire, Perry J. Blackshear, Kirsty F. MacKenzie
Publikováno v:
Molecular and cellular biology. 33(7)
Prostaglandin production is catalyzed by cyclooxygenase 2 (cox-2). We demonstrate here that MSK1 and MSK2 (MSK1/2) can exert control on the induction of cox-2 mRNA by Toll-like receptor (TLR) agonists. In the initial phase of cox-2 induction, MSK1/2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc778900281dc33528d2ee1c629ff2b
http://ora.ox.ac.uk/objects/uuid:6bf457c3-e9ce-4b9f-8bc8-4010d6b20680
http://ora.ox.ac.uk/objects/uuid:6bf457c3-e9ce-4b9f-8bc8-4010d6b20680