Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Victoria A. Lukashkina"'
Autor:
Yukako Asai, Bifeng Pan, Carl Nist-Lund, Alice Galvin, Andrei N. Lukashkin, Victoria A. Lukashkina, Tianwen Chen, Wu Zhou, Hong Zhu, Ian J. Russell, Jeffrey R. Holt, Gwenaelle S. G. Géléoc
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Recent work has demonstrated that transmembrane channel-like 1 protein (TMC1) is an essential component of the sensory transduction complex in hair cells of the inner ear. A closely related homolog, TMC2, is expressed transiently in the neon
Externí odkaz:
https://doaj.org/article/7060bb4179c3426d8a8e22cd46477d42
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The sharp frequency tuning and exquisite sensitivity of the mammalian cochlea is due to active forces delivered by outer hair cells (OHCs) to the cochlear partition. Force transmission is mediated and modulated by specialized cells, includin
Externí odkaz:
https://doaj.org/article/d05a16c138454ed4b1706eae3d823603
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
A point mutation in the gap-junction protein connexin 30 stops early onset age-related hearing loss. Here, the authors show that gap junctions contribute to cochlear micromechanics and that cochlear amplification is likely controlled by extracellular
Externí odkaz:
https://doaj.org/article/db9279e8479c4eafbe4a3235a3fa6f72
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number: 14530 (2017); Published 21 February 2017; Updated 21 March 2017 The financial support for this Article was not fully acknowledged. The Acknowledgements should have included the following: The research was fund
Externí odkaz:
https://doaj.org/article/746b971530f44ec3947bf98055d0151c
Autor:
Victoria A. Lukashkina, Snezana Levic, Patrício Simões, Zhenhang Xu, Joseph A. DiGuiseppi, Jian Zuo, Andrei N. Lukashin, Ian J. Russell
Publikováno v:
J Neurosci
Cochlear sensitivity, essential for communication and exploiting the acoustic environment, results from sensory-motor outer hair cells (OHCs) operating in a structural scaffold of supporting cells and extracellular cortilymph within the organ of Cort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f71bf8631e400aa9d74170306fed487
https://europepmc.org/articles/PMC9302466/
https://europepmc.org/articles/PMC9302466/
Publikováno v:
J Neurosci
Cochlear amplification enables the enormous dynamic range of hearing through amplifying cochlear responses to low- to moderate-level sounds and compressing them to loud sounds. Amplification is attributed to voltage-dependent electromotility of mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf36d1d428a6f3df80fc3e0c4d9b065
https://pubmed.ncbi.nlm.nih.gov/36261265
https://pubmed.ncbi.nlm.nih.gov/36261265
SummaryCochlear amplification, whereby cochlear responses to low-to-moderate sound levels are amplified and compressed to loud sounds, is attributed to outer hair cell (OHC) electromotility driven by voltage changes across the OHC basolateral membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfd770b3f7b4cb5488c2304fd24debfb
https://doi.org/10.1101/2021.08.11.455955
https://doi.org/10.1101/2021.08.11.455955
Autor:
Snezana Levic, Victoria A. Lukashkina, Andrei N. Lukashkin, Jian Zuo, Ian J. Russell, Zhenhang Xu, Joseph DiGuiseppi, Patricio Simoes
Cochlear sensitivity, essential for communication and exploiting the acoustic environment, is due to the sensory-motor outer hair cells (OHCs) that operate in the structural scaffold of supporting cells and extracellular spaces in the cochlear organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::880c3c3418a616cdf5a51e57356c614a
https://doi.org/10.21203/rs.3.rs-92461/v2
https://doi.org/10.21203/rs.3.rs-92461/v2
Autor:
Snezana Levic, Victoria A. Lukashkina, Patricio Simoes, Ian J. Russell, Jian Zuo, Andrei N. Lukashkin, Joseph DiGuiseppi, Zhenhang Xu
We used optogenetics to investigate the control of auditory sensitivity by cochlear supporting cells that scaffold outer hair cells, which transduce and amplify cochlear responses to sound. In vivo and in vitro measurements of sound-induced cochlear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee24ac4d76e942a8a1c1e8fbefe1861f
https://doi.org/10.21203/rs.3.rs-92461/v1
https://doi.org/10.21203/rs.3.rs-92461/v1
Autor:
Andrei N. Lukashkin, Victoria A. Lukashkina, Snezana Levic, Lily Ng, Young Wook Cho, Ian J. Russell, Douglas Forrest
Publikováno v:
Science Advances
A protein in the cochlear basilar membrane promotes frequency-specific mechanical responses and auditory frequency resolution.
The detection of different frequencies in sound is accomplished with remarkable precision by the basilar membrane (BM)
The detection of different frequencies in sound is accomplished with remarkable precision by the basilar membrane (BM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc4df57fdbecc4df55176c8ce66b5c3
http://europepmc.org/articles/PMC7286672
http://europepmc.org/articles/PMC7286672