Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Victoria A. Kimler"'
Publikováno v:
Molecular Metabolism, Vol 7, Iss , Pp 57-70 (2018)
Objective: Brown adipose tissue (BAT) thermogenesis depends on the mobilization and oxidation of fatty acids from intracellular lipid droplets (LD) within brown adipocytes (BAs); however, the identity and function of LD proteins that control BAT lipo
Externí odkaz:
https://doaj.org/article/4488d220f1d8491b850159cfb8478790
Autor:
Hyunbae Kim, Xuequn Chen, Jiandie D. Lin, Dreana Williams, Andrew F.X. Goldberg, Zhenfeng Song, Li Wang, Deyu Fang, Victoria A. Kimler, Yining Qiu, Zengquann Yang, Ren Zhang, Zhao Yang, Kezhong Zhang
Publikováno v:
FASEB J
Autophagy, a lysosomal degradative pathway in response to nutrient limitation, plays an important regulatory role in lipid homeostasis upon energy demands. Here, we demonstrated that the endoplasmic reticulum–tethered, stress-sensing transcription
Autor:
James G. Granneman, Mita Varghese, Guy Perkins, Fariha R. Ghazi, Victoria A. Kimler, Mark H. Ellisman, Gurnoor K. Rathore
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
This study investigated the effects of elevated fatty acid (FA) supply from adipose tissue on the ultrastructure of cardiac lipid droplets (LDs) and the expression and organization of LD scaffold proteins perilipin-2 (PLIN2) and perilipin-5 (PLIN5).
Autor:
Anthony Premceski, Eric Seidel, Jonathan Cheon, Anbarasu Kumarasamy, Sivakumar Jeyarajan, Frank J. Giblin, Victoria A. Kimler
Publikováno v:
Exp Eye Res
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the authors. The senior author contacted th
Publikováno v:
Molecular Metabolism, Vol 7, Iss, Pp 57-70 (2018)
Molecular Metabolism
Molecular Metabolism
Objective Brown adipose tissue (BAT) thermogenesis depends on the mobilization and oxidation of fatty acids from intracellular lipid droplets (LD) within brown adipocytes (BAs); however, the identity and function of LD proteins that control BAT lipol
Autor:
Anthony Premceski, Jonathan Cheon, Eric Seidel, Victoria A. Kimler, Anbarasu Kumarasamy, Sivakumar Jeyarajan, Frank J. Giblin
Publikováno v:
Experimental Eye Research. 194:107990
αA(66−80) peptide forms with age in the lens nucleus of humans and guinea pigs, and binds to αA-crystallin by hydrophobic bonds to produce protein aggregates. The purpose of the present study was to use negative-stain transmission electron micros
Autor:
Andrew F.X. Goldberg, Tanya L. Dilan, Abigail R. Moye, Ratnesh K. Singh, Victoria A. Kimler, Visvanathan Ramamurthy, Daniella Munezero, Thamaraiselvi Saravanan
Publikováno v:
Molecular biology of the cell. 29(13)
The outer segment (OS) of photoreceptor cells is an elaboration of a primary cilium with organized stacks of membranous disks that contain the proteins needed for phototransduction and vision. Though ciliary formation and function has been well chara
Autor:
Victoria A. Kimler, John H. Postlethwait, Ryan Thummel, Xixia Luo, James G. Granneman, Xiangqun Ye, Huamei Zhang
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Perilipin (PLIN) proteins constitute an ancient family important in lipid droplet (LD) formation and triglyceride metabolism. We identified an additional PLIN clade (plin6) that is unique to teleosts and can be traced to the two whole genome duplicat
Publikováno v:
Journal of Animal Science. 89:701-710
The storage and mobilization of lipid energy are central functions of adipocytes. Lipid energy is stored as triglyceride in lipid droplet structures that are now recognized as bona fide organelles and whose functions are greatly influenced by members
Autor:
James M. Montante, Mary Tracy-Bee, Charles R. C. Marks, D. Carl Freeman, Candace D. Ollie, Victoria A. Kimler, R. Anton Hough, Renee M. Langer, John D. Taylor
Publikováno v:
Pigment Cell Research. 17:165-172
Fractal or focal dimension (FD) analysis is a valuable tool to identify physiologic stimuli at the cellular and tissue levels that allows for quantification of cell perimeter complexity. The FD analysis was determined on fluorescence images of caffei