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Autor:
Shwetha, Ramachandrappa, Anne, Raimondo, Anna M G, Cali, Julia M, Keogh, Elana, Henning, Sadia, Saeed, Amanda, Thompson, Sumedha, Garg, Elena G, Bochukova, Soren, Brage, Victoria, Trowse, Eleanor, Wheeler, Adrienne E, Sullivan, Mehul, Dattani, Peter E, Clayton, Vipan, Datta, Vippan, Datta, John B, Bruning, Nick J, Wareham, Stephen, O'Rahilly, Daniel J, Peet, Ines, Barroso, Murray L, Whitelaw, I Sadaf, Farooqi
Publikováno v:
Journal of Clinical Investigation; Vol 123
Journal of Clinical Investigation
Journal of Clinical Investigation
Single-minded 1 (SIM1) is a basic helix-loop-helix transcription factor involved in the development and function of the paraventricular nucleus of the hypothalamus. Obesity has been reported in Sim1 haploinsufficient mice and in a patient with a bala