Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Victoria, Lunz"'
Autor:
Christine Silvia Gibhardt, Sabrina Cappello, Rajesh Bhardwaj, Romana Schober, Sonja Agnes Kirsch, Zuriñe Bonilla del Rio, Stefan Gahbauer, Anna Bochicchio, Magdalena Sumanska, Christian Ickes, Ioana Stejerean-Todoran, Miso Mitkovski, Dalia Alansary, Xin Zhang, Aram Revazian, Marc Fahrner, Victoria Lunz, Irene Frischauf, Ting Luo, Daria Ezerina, Joris Messens, Vsevolod Vadimovich Belousov, Markus Hoth, Rainer Arnold Böckmann, Matthias Albrecht Hediger, Rainer Schindl, Ivan Bogeski
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108292- (2020)
Summary: Store-operated calcium entry (SOCE) through STIM-gated ORAI channels governs vital cellular functions. In this context, SOCE controls cellular redox signaling and is itself regulated by redox modifications. However, the molecular mechanisms
Externí odkaz:
https://doaj.org/article/9aa210ab347a4829a53ce714c6a1e9f1
Autor:
Adéla Tiffner, Valentina Hopl, Romana Schober, Matthias Sallinger, Herwig Grabmayr, Carmen Höglinger, Marc Fahrner, Victoria Lunz, Lena Maltan, Irene Frischauf, Denis Krivic, Rajesh Bhardwaj, Rainer Schindl, Matthias A. Hediger, Isabella Derler
Publikováno v:
Cancers, Vol 13, Iss 24, p 6357 (2021)
The interplay of SK3, a Ca2+ sensitive K+ ion channel, with Orai1, a Ca2+ ion channel, has been reported to increase cytosolic Ca2+ levels, thereby triggering proliferation of breast and colon cancer cells, although a molecular mechanism has remained
Externí odkaz:
https://doaj.org/article/66683336ac42453dbca136ac9d665771
Autor:
Matthias Sallinger, Adéla Tiffner, Tony Schmidt, Daniel Bonhenry, Linda Waldherr, Irene Frischauf, Victoria Lunz, Isabella Derler, Romana Schober, Rainer Schindl
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4410 (2020)
Stromal interaction molecule 1 (STIM1) is a ubiquitously expressed Ca2+ sensor protein that induces permeation of Orai Ca2+ channels upon endoplasmic reticulum Ca2+-store depletion. A drop in luminal Ca2+ causes partial unfolding of the N-terminal ST
Externí odkaz:
https://doaj.org/article/fb9d8fc255c8464eb92a6f2a72999084
Autor:
Derler, Adéla Tiffner, Valentina Hopl, Romana Schober, Matthias Sallinger, Herwig Grabmayr, Carmen Höglinger, Marc Fahrner, Victoria Lunz, Lena Maltan, Irene Frischauf, Denis Krivic, Rajesh Bhardwaj, Rainer Schindl, Matthias A. Hediger, Isabella
Publikováno v:
Cancers; Volume 13; Issue 24; Pages: 6357
The interplay of SK3, a Ca2+ sensitive K+ ion channel, with Orai1, a Ca2+ ion channel, has been reported to increase cytosolic Ca2+ levels, thereby triggering proliferation of breast and colon cancer cells, although a molecular mechanism has remained
Autor:
Sonja Lindinger, Saurabh Pandey, Adéla Tiffner, Isabella Derler, Michael Stadlbauer, Victoria Lunz, Daniel Bonhenry, Rudi Ettrich, Irene Frischauf, Matthias Sallinger, Marc Fahrner, Christoph Romanin, Lena Maltan, Sascha Berlansky, Rainer Schindl, Romana Schober, Carmen Hoeglinger
The initial activation step in gating of ubiquitously expressed Orai1 Calcium (Ca2+) ion channels represents the store-dependent coupling to the Ca2+ sensor protein STIM1. An array of constitutively active Orai1 mutants gave rise to the hypothesis th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5a605ab39dd19a2e1115dfd3781cef8
https://doi.org/10.1101/2020.07.16.207183
https://doi.org/10.1101/2020.07.16.207183
Autor:
Romana, Schober, Daniel, Bonhenry, Victoria, Lunz, Jinhui, Zhu, Adela, Krizova, Irene, Frischauf, Marc, Fahrner, MengQi, Zhang, Linda, Waldherr, Tony, Schmidt, Isabella, Derler, Peter B, Stathopulos, Christoph, Romanin, Rüdiger H, Ettrich, Rainer, Schindl
Publikováno v:
Science signaling. 12(608)
The stromal interaction molecule 1 (STIM1) has two important functions, Ca
Autor:
Rüdiger Ettrich, Irene Frischauf, Rainer Schindl, Linda Waldherr, Adéla Krizova, MengQi Zhang, Tony Schmidt, Isabella Derler, Jinhui Zhu, Romana Schober, Christoph Romanin, Victoria Lunz, Marc Fahrner, Peter B. Stathopulos, Daniel Bonhenry
Publikováno v:
Science Signaling. 12
The stromal interaction molecule 1 (STIM1) has two important functions, Ca2+ sensing within the endoplasmic reticulum and activation of the store-operated Ca2+ channel Orai1, enabling plasma-membrane Ca2+ influx. We combined molecular dynamics (MD) s
Autor:
Carmen, Butorac, Martin, Muik, Isabella, Derler, Michael, Stadlbauer, Victoria, Lunz, Adéla, Krizova, Sonja, Lindinger, Romana, Schober, Irene, Frischauf, Rajesh, Bhardwaj, Matthias A, Hediger, Klaus, Groschner, Christoph, Romanin
Publikováno v:
Cell calcium. 79
Calcium signalling through store-operated calcium (SOC) entry is of crucial importance for T-cell activation and the adaptive immune response. This entry occurs via the prototypic Ca
Publikováno v:
Cell calcium. 77
A primary calcium (Ca
Autor:
Sabrina Cappello, Anna Hochreiter, Ivan Bogeski, Irene Frischauf, Laura Tociu, Rüdiger Ettrich, Rainer Schindl, Christoph Romanin, Vasilina Zayats, Victoria Lunz, Martin Muik, Klaus Groschner, Amrutha Stallinger, Monika Litviňuková, Teresa Pammer, David Reha, Romana Schober, Daniel Bonhenry, Barbora Svobodova, Carmen Butorac
Publikováno v:
Science signaling. 10(507)
The channel Orai1 requires Ca2+ store depletion in the endoplasmic reticulum and an interaction with the Ca2+ sensor STIM1 to mediate Ca2+ signaling. Alterations in Orai1-mediated Ca2+ influx have been linked to several pathological conditions includ