Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Victoria, Bae-Jump"'
Autor:
Boer Deng, Weimin Kong, Xiaochang Shen, Chao Han, Ziyi Zhao, Shuning Chen, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Lipid metabolism is widely reprogrammed in tumor cells. Lipid droplet is a common organelle existing in most mammal cells, and its complex and dynamic functions in maintaining redox and metabolic balance, regulating endoplasmic reticulum str
Externí odkaz:
https://doaj.org/article/c67425a3a108493c907edc3797d944cf
Autor:
Jianqing Qiu, Ziyi Zhao, Hongyan Suo, Sarah E. Paraghamian, Gabrielle M. Hawkins, Wenchuan Sun, Xin Zhang, Tianran Hao, Beor Deng, Xiaochang Shen, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
ABSTRACTEmerging evidence has provided considerable insights into the integral function of reprogramming fatty acid metabolism in the carcinogenesis and progression of endometrial cancer. Linoleic acid, an essential fatty acid with the highest consum
Externí odkaz:
https://doaj.org/article/0a883326542640ba9fd25fa4fea02307
Autor:
Janina Pearce, Caitlin Durr, Xufeng Qu, Jinze Liu, Leslie Randall, Devin Miller, Sadia Sayeed, Victoria Bae-Jump, Stephanie Sullivan
Publikováno v:
Gynecologic Oncology Reports, Vol 52, Iss , Pp 101360- (2024)
Objective: Endometrial cancer (EC) incidence and mortality are increasing with striking racial disparities. Race and obesity are known risk factors for EC, however, their relationship and impact on tumor biology in higher grade endometrioid EC are un
Externí odkaz:
https://doaj.org/article/470c11da6866428aa530153c10b7eb16
Autor:
Wesley C. Burkett, Ziyi Zhao, Meredith A. Newton, Wenchuan Sun, Boer Deng, Angeles Alvarez Secord, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
Annals of Medicine, Vol 55, Iss 1, Pp 603-614 (2023)
AbstractPurpose Uterine serous carcinoma (USC) exhibits worse survival rates compared to the endometrioid subtype, and there is currently no effective treatment options for recurrence of this disease after platinum-based chemotherapy. Activation of P
Externí odkaz:
https://doaj.org/article/ecb88b1b26b24a17813aa38f363d5220
Autor:
Xiaochang Shen, Jiandong Wang, Boer Deng, Ziyi Zhao, Shuning Chen, Weimin Kong, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 617 (2024)
Ascorbate (vitamin C) is an essential vitamin for the human body and participates in various physiological processes as an important coenzyme and antioxidant. Furthermore, the role of ascorbate in the prevention and treatment of cancer including gyne
Externí odkaz:
https://doaj.org/article/b172da910468458ab728df31ebcc7cb2
Autor:
Sarah E. Paraghamian, Jianqing Qiu, Gabrielle M. Hawkins, Ziyi Zhao, Wenchuan Sun, Yali Fan, Xin Zhang, Hongyan Suo, Tianran Hao, Varun Vijay Prabhu, Joshua E. Allen, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
Cancer Biology & Therapy, Vol 24, Iss 1 (2023)
Poly ADP-ribose polymerase (PARP) inhibitors are effective therapies for cancer patients with homologous recombination (HR) deficient tumors. The imipridone ONC206 is an orally bioavailable dopamine receptor D2 antagonist and mitochondrial protease C
Externí odkaz:
https://doaj.org/article/22955f4a08a9470987b40e5ec77a2a17
Autor:
Guangxu Xu, Ziyi Zhao, Weiya Z. Wysham, Dario R. Roque, Ziwei Fang, Wenchuan Sun, Yajie Yin, Boer Deng, Xiaochang Shen, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionAmong all cancers, endometrial cancer is most strongly associated with obesity, with more than 65% of endometrial cancers attributable to obesity and being overweight. Fatty acid synthase (FAS), a key lipogenic enzyme, is expressed in end
Externí odkaz:
https://doaj.org/article/427e4750c2fb4b57b74994c44a71feb7
Autor:
Yu Huang, Yali Fan, Ziyi Zhao, Xin Zhang, Katherine Tucker, Allison Staley, Hongyan Suo, Wenchuan Sun, Xiaochang Shen, Boer Deng, Stuart R. Pierce, Lindsay West, Yajie Yin, Michael J. Emanuele, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12375 (2023)
Ovarian cancer is the deadliest gynecological malignancy of the reproductive organs in the United States. Cyclin-dependent kinase 1 (CDK1) is an important cell cycle regulatory protein that specifically controls the G2/M phase transition of the cell
Externí odkaz:
https://doaj.org/article/2663c66e5bbc42a9a40efaeb17fceb1f
Autor:
Wendy R. Brewster, Wesley C. Burkett, Emily M. Ko, Victoria Bae-Jump, Amber Nicole McCoy, Temitope O. Keku
Publikováno v:
Gynecologic Oncology Reports, Vol 42, Iss , Pp 101017- (2022)
Objective: The microbiome of the female upper reproductive tract (URT) has not been characterized. We hypothesize that distinct bacterial species may be identified in different areas of the URT in women with or without ovarian cancers. Methods: Postm
Externí odkaz:
https://doaj.org/article/0d2d90ee4c4a4231b11eca1bd07e3de1
Autor:
Stuart R. Pierce, Ziwei Fang, Yajie Yin, Lindsay West, Majdouline Asher, Tianran Hao, Xin Zhang, Katherine Tucker, Allison Staley, Yali Fan, Wenchuan Sun, Dominic T. Moore, Chang Xu, Yi-Hsuan Tsai, Joel Parker, Varun Vijay Prabhu, Joshua E. Allen, Douglas Lee, Chunxiao Zhou, Victoria Bae-Jump
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-15 (2021)
Abstract Background ONC201 is a dopamine receptor D2 (DRD2) antagonist that inhibits tumor growth in preclinical models through ClpP activation to induce integrated stress response pathway and mitochondrial events related to inhibition of cell growth
Externí odkaz:
https://doaj.org/article/0bf0764955fb4c44a847f4becd71ad3c