Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Victor Solodushko"'
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
DNA vaccines have great potential to control infectious disease, particularly those caused by intracellular organisms. They are inexpensive to produce and can be quickly modified to combat emerging infectious threats, but often fail to generate a str
Externí odkaz:
https://doaj.org/article/8df21b8f08804c72a102eda875b6e776
Autor:
Jonathan O. Rayner, Jin Hyun Kim, Rosemary W. Roberts, Raphael Ryan Wood, Brian Fouty, Victor Solodushko
Publikováno v:
Vaccines, Vol 9, Iss 4, p 345 (2021)
Chikungunya virus (CHIKV) infection can result in chronic and debilitating arthralgia affecting humans in tropical and subtropical regions around the world, yet there are no licensed vaccines to prevent infection. DNA launched virus like particle (VL
Externí odkaz:
https://doaj.org/article/c170ddde05d4476d9235c36f7ed78244
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Minimal piggyBac vectors are a modified single-plasmid version of the classical piggyBac delivery system that can be used for stable transgene integration. These vectors have a truncated terminal domain in the delivery cassette and thus, integrate si
Externí odkaz:
https://doaj.org/article/1454676823654ed1b7ddd57d74c45add
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71490 (2013)
Pulmonary artery endothelial cells (PAEC) in an intact vessel are continually exposed to serum, but unless injured, do not proliferate, constrained by confluence. In contrast, pulmonary artery smooth muscle cells (PASMC) attain, and maintain, conflue
Externí odkaz:
https://doaj.org/article/ee1600c4c4f44d20bc50a66134aaec84
Autor:
Victor Solodushko, Brian Fouty
Publikováno v:
Gene Therapy.
Synthesizing mRNA in vitro is a standard and simple procedure. Adding the 5′ cap and 3′ polyadenylated (poly(A)) tail to make this mRNA functional for use as a vaccine or therapy increases the time and cost of production and usually decreases the
Autor:
Rosemary W. Roberts, Jin Hyun Kim, Brian Fouty, Victor Solodushko, Raphael Ryan Wood, Jonathan O. Rayner
Publikováno v:
Vaccines
Volume 9
Issue 4
Vaccines, Vol 9, Iss 345, p 345 (2021)
Volume 9
Issue 4
Vaccines, Vol 9, Iss 345, p 345 (2021)
Chikungunya virus (CHIKV) infection can result in chronic and debilitating arthralgia affecting humans in tropical and subtropical regions around the world, yet there are no licensed vaccines to prevent infection. DNA launched virus like particle (VL
Publikováno v:
Journal of Fluorescence. 24:305-311
Tetracycline-inducible systems allow for either suppression or induction of transgene expression to facilitate studies of cell physiology. Doxycycline is a preferred inducer for these gene expression systems due to its membrane permeability; however,
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Minimal piggyBac vectors are a modified single-plasmid version of the classical piggyBac delivery system that can be used for stable transgene integration. These vectors have a truncated terminal domain in the delivery cassette and thus, integrate si
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 300:L642-L647
p19ARFis a tumor suppressor that leads to cell cycle arrest or apoptosis by stabilizing p53. p19ARFis not critical for cell cycle regulation under normal conditions, but loss of p19ARFis seen in many human cancers, and a murine p19Arfknockout model l
Autor:
Victor Solodushko, Brian Fouty
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 292:L671-L677
Endothelial cells perform a number of important functions including release of vasodilators, control of the coagulation cascade, and restriction of solutes and fluid from the extravascular space. Regulation of fluid balance is of particular importanc