Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Victor Sipido"'
Autor:
Javier Fernández, Andrés A. Trabanco, Victor Sipido, José Ignacio Andrés, José María Cid, Anton Megens, Pilar Gil, J. Alonso, Laura Iturrino, Adolfo Dı́az
Publikováno v:
Journal of Medicinal Chemistry. 48:1709-1712
A series of novel tetracyclic tetrahydrofuran derivatives was prepared and evaluated for its potential psychotropic properties. In vitro affinities for multiple dopaminergic, serotonergic, alpha-adrenergic, and histamine receptors and for the norepin
Autor:
Encarna Matesanz, José Manuel Alonso, Jesús Alcázar, Pilar Gil, Laura Iturrino, J. Ignacio Andres, Javier Fernández, Victor Sipido, Theo F. Meert, Anton Megens, Adolfo Dı́az
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(2)
The synthesis of a series of novel 2-(aminoalkyl)-2,3,3a,8-tetrahydrodibenzo[c,f]isoxazolo[2,3-a]azepine derivatives as well as their 5-HT(2A/2C) and H(1) receptor binding affinities are described. The in vivo activity as potential anxiolytics of the