Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Victor Sebastián"'
Autor:
Ainhoa Fernández‐Tena, Itziar Otaegi, Lourdes Irusta, Victor Sebastián, Gonzalo Guerrica‐Echevarria, Alejandro Jesus Müller, Nora Aranburu
Publikováno v:
Macromolecular Materials and Engineering, Vol 308, Iss 12, Pp n/a-n/a (2023)
Abstract In this work, the effectiveness of seven commercial compatibilizers is tested in polylactide (PLA)/poly(ε‐caprolactone) (PCL) blends with different compositions to obtain a high‐impact PLA. None of the compatibilizers is effective for 9
Externí odkaz:
https://doaj.org/article/9537670a32ee416b9c52fec0fa859319
Autor:
Lorenzo Suigo, William Margolin, Eugenia Ulzurrun, Martina Hrast Rambaher, Carlo Zanotto, Victor Sebastián-Pérez, Nuria E. Campillo, Valentina Straniero, Ermanno Valoti
Publikováno v:
Antibiotics, Vol 12, Iss 12, p 1712 (2023)
FtsZ is an essential bacterial protein abundantly studied as a novel and promising target for antimicrobials. FtsZ is highly conserved among bacteria and mycobacteria, and it is crucial for the correct outcome of the cell division process, as it is r
Externí odkaz:
https://doaj.org/article/cd0c71cb92954c3d972391d7f24dd304
Autor:
María Sancho‐Albero, Miguel Encinas‐Giménez, Victor Sebastián, Estela Pérez, Lluís Luján, Jesús Santamaría, Pilar Martin‐Duque
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 3, Pp n/a-n/a (2022)
Abstract The main current challenges in oncology are (1) avoiding systemic side effects in therapy, and (2) developing alternative treatment strategies for metastatic tumours. Nanomedicine was assumed to provide answers to these issues, but deliverin
Externí odkaz:
https://doaj.org/article/d232b8ca6ed5447cb10ba2b6478910f3
Autor:
Paula Martínez de Iturrate, Victor Sebastián-Pérez, Montserrat Nácher-Vázquez, Catherine S. Tremper, Despina Smirlis, Julio Martín, Ana Martínez, Nuria E. Campillo, Luis Rivas, Carmen Gil
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 199-210 (2020)
Previous reports have validated the glycogen synthase kinase-3 (GSK-3) as a druggable target against the human protozoan parasite Leishmania. This prompted us to search for new leishmanicidal scaffolds as inhibitors of this enzyme from our in-house l
Externí odkaz:
https://doaj.org/article/3b09ef3f651f4ec6a08ecd783dbfddba
Autor:
Silvia Nalesso, Gaelle Varlet, Madeleine J. Bussemaker, Richard P. Sear, Mark Hodnett, Rebeca Monteagudo-Oliván, Victor Sebastián, Joaquín Coronas, Judy Lee
Publikováno v:
Ultrasonics Sonochemistry, Vol 76, Iss , Pp 105616- (2021)
A systematic study on the sonocrystallisation of ZIF-8 (zeolitic imidazolate framework-8) in a water-based system was investigated under different mixing speeds, ultrasound frequencies, calorimetric powers and sonication time. Regardless of the synth
Externí odkaz:
https://doaj.org/article/f76b6c86f472431697663999c79ce033
Autor:
Sanaa S. Botros, Samia William, Abdel-Nasser A. Sabra, Naglaa M. El-Lakkany, Sayed H. Seif el-Din, Alfonso García-Rubia, Victor Sebastián-Pérez, Antoni R. Blaazer, Erik de Heuvel, Maarten Sijm, Yang Zheng, Irene G. Salado, Jane C. Munday, Louis Maes, Iwan J.P. de Esch, Geert J. Sterk, Koen Augustyns, Rob Leurs, Carmen Gil, Harry P. De Koning
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 9, Iss , Pp 35-43 (2019)
We report the evaluation of 265 compounds from a PDE-focused library for their antischistosomal activity, assessed in vitro using Schistosoma mansoni. Of the tested compounds, 171 (64%) displayed selective in vitro activity, with 16 causing worm hype
Externí odkaz:
https://doaj.org/article/cdcde76f0d614f8da6d01b3d4b7709e4
Autor:
M. Lourdes Sciú, Victor Sebastián-Pérez, Loreto Martinez-Gonzalez, Rocio Benitez, Daniel I. Perez, Concepción Pérez, Nuria E. Campillo, Ana Martinez, E. Laura Moyano
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 87-96 (2019)
Numerous studies have highlighted the implications of the glycogen synthase kinase 3 (GSK-3) in several processes associated with Alzheimer’s disease (AD). Therefore, GSK-3 has become a crucial therapeutic target for the treatment of this neurodege
Externí odkaz:
https://doaj.org/article/02eaf3ea1ac54fe49215488f90ef2ccd
Publikováno v:
Micromachines, Vol 13, Iss 6, p 878 (2022)
A facile and robust microfluidic method to produce nanoparticle-in-microparticle systems (Trojan systems) is reported as a delivery vector for the oral administration of active pharmaceutical ingredients. The microfluidic system is based on two coaxi
Externí odkaz:
https://doaj.org/article/f4b0eebd0cc64702bd62606b83405ebd
Autor:
Victor Sebastián-Pérez, Paula Martínez de Iturrate, Montserrat Nácher-Vázquez, Luis Nóvoa, Concepción Pérez, Nuria E. Campillo, Carmen Gil, Luis Rivas
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1136 (2022)
More than 1 billion people live in areas endemic for leishmaniasis, which is a relevant threat for public health worldwide. Due to the inadequate treatments, there is an urgent need to develop novel alternative drugs and to validate new targets to fi
Externí odkaz:
https://doaj.org/article/ce30c60ca1094e89aab2b03ea997b1f8
Autor:
Lorenzo Suigo, Michaelle Chojnacki, Carlo Zanotto, Victor Sebastián-Pérez, Carlo De Giuli Morghen, Andrea Casiraghi, Paul M. Dunman, Ermanno Valoti, Valentina Straniero
Publikováno v:
Antibiotics, Vol 10, Iss 4, p 438 (2021)
Antibiotic resistance is spreading worldwide and it has become one of the most important issues in modern medicine. In this context, the bacterial RNA degradation and processing machinery are essential processes for bacterial viability that may be ex
Externí odkaz:
https://doaj.org/article/483bc5da406343679a6d9960a652b3e4