Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Victor S, Tapia"'
Autor:
Rose Wellens, Victor S. Tapia, Paula I. Seoane, Hayley Bennett, Antony Adamson, Graham Coutts, Jack Rivers-Auty, Martin Lowe, Jack P. Green, Gloria Lopez-Castejon, David Brough, Christopher Hoyle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Interleukin-1α is a suggested dual-function cytokine that diverged from interleukin-1β in mammals potentially by acquiring additional biological roles that relate to highly conserved regions in the pro-domain of interleukin-1α, including
Externí odkaz:
https://doaj.org/article/bc0dba57dbec420e841cbe42a9a405ca
Autor:
Sarah E. Withers, Charlie F. Rowlands, Victor S. Tapia, Frances Hedley, Ioana-Emilia Mosneag, Siobhan Crilly, Gillian I. Rice, Andrew P. Badrock, Andrew Hayes, Stuart M. Allan, Tracy A. Briggs, Paul R. Kasher
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Aicardi-Goutières syndrome (AGS1-9) is a genetically determined encephalopathy that falls under the type I interferonopathy disease class, characterized by excessive type I interferon (IFN-I) activity, coupled with upregulation of IFN-stimulated gen
Externí odkaz:
https://doaj.org/article/21996985323c40e7b3c222331fcef159
Autor:
Siobhan Crilly, Adrian Parry-Jones, Xia Wang, Julian N. Selley, James Cook, Victor S. Tapia, Craig S. Anderson, Stuart M. Allan, Paul R. Kasher
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 3 (2022)
Despite the global health burden, treatment of spontaneous intracerebral haemorrhage (ICH) is largely supportive, and translation of specific medical therapies has not been successful. Zebrafish larvae offer a unique platform for drug screening to ra
Externí odkaz:
https://doaj.org/article/3a6cbe4f2e264bf9a3f740c81571b953
Autor:
Alison E. Mather, Jack Rivers-Auty, Harry G. Spence, Christopher Hoyle, Michael J.D. Daniels, Shi Yu, Margaret Jane Gordon, James Cook, David Brough, Paul T. Kennedy, John H. Beattie, Amy Bradley, Victor S. Tapia, Ruth Peters, Samuel Drinkall, Te-Chen Tzeng, Claire S. White, Catherine B. Lawrence, Jack Peter Green
Publikováno v:
The Journal of Neuroscience
Alzheimer's disease is a devastating neurodegenerative disease with a dramatically increasing prevalence and no disease-modifying treatment. Inflammatory lifestyle factors increase the risk of developing Alzheimer's disease. Zinc deficiency is the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7018a3cbf7c3fb7a28bf046d53d9335
http://europepmc.org/articles/PMC8018890
http://europepmc.org/articles/PMC8018890
Publikováno v:
Regeneration. 4:21-35
Xenopus laevis tadpoles can regenerate the spinal cord after injury but this capability is lost during metamorphosis. Comparative studies between pre-metamorphic and metamorphic Xenopus stages can aid towards understanding the molecular mechanisms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eeb10b2a170be9ea84364beddb890f3
https://doi.org/10.1002/reg2.74
https://doi.org/10.1002/reg2.74
Autor:
Victor S, Tapia, Michael J D, Daniels, Pablo, Palazón-Riquelme, Matthew, Dewhurst, Nadia M, Luheshi, Jack, Rivers-Auty, Jack, Green, Elena, Redondo-Castro, Philipp, Kaldis, Gloria, Lopez-Castejon, David, Brough
Publikováno v:
The Journal of Biological Chemistry
Interleukin (IL)-1 family cytokines potently regulate inflammation, with the majority of the IL-1 family proteins being secreted from immune cells via unconventional pathways. In many cases, secretion of IL-1 cytokines appears to be closely coupled t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4bc970a802f25a9a3aae02c018dda128
https://pubmed.ncbi.nlm.nih.gov/30940725
https://pubmed.ncbi.nlm.nih.gov/30940725
Autor:
Victor S. Tapia, Juan Larraín, Emilio E. Méndez-Olivos, Gabriela Edwards-Faret, Dasfne Lee-Liu, Rosana Muñoz
Publikováno v:
Nature protocols. 12(2)
Here we present a protocol for the husbandry of Xenopus laevis tadpoles and froglets, and procedures to study spinal cord regeneration. This includes methods to induce spinal cord injury (SCI); DNA and morpholino electroporation for genetic studies;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c910b4f42fd775465be80c03382f6720
https://pubmed.ncbi.nlm.nih.gov/28102835
https://pubmed.ncbi.nlm.nih.gov/28102835
Publikováno v:
genesis. 51:529-544
Unlike mammals, regenerative model organisms such as amphibians and fish are capable of spinal cord regeneration after injury. Certain key differences between regenerative and nonregenerative organisms have been suggested as involved in promoting thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b375a732f112b91be938a98844d73b3f
https://doi.org/10.1002/dvg.22406
https://doi.org/10.1002/dvg.22406
Autor:
Juan Larraín, Victor S. Tapia
Publikováno v:
Recovery of Motor Function Following Spinal Cord Injury
JAK-STAT signalling is a main transduction pathway of cytokines and growth factors, which is involved in several biological processes including cell proliferation, cell differentiation, axon regeneration, apoptosis and inflammation. After spinal cord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e12ad6ef58a1b1c0ebad69a837bd010d
https://doi.org/10.5772/63418
https://doi.org/10.5772/63418
