Challenges in Discovering Drugs That Target the Protein–Protein Interactions of Disordered Proteins

Autor: Judit Oláh, Tibor Szénási, Attila Lehotzky, Victor Norris, Judit Ovádi

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 3, p 1550 (2022)

Protein–protein interactions (PPIs) outnumber proteins and are crucial to many fundamental processes; in consequence, PPIs are associated with several pathological conditions including neurodegeneration and modulating them by drugs constitutes a po

Externí odkaz: https://doaj.org/article/c447f9107e804ed688b32dd21efb411e

Combining combing and secondary ion mass spectrometry to study DNA on chips using 13C and 15N labeling [version 1; referees: 2 approved]

Autor: Armelle Cabin-Flaman, Anne-Francoise Monnier, Yannick Coffinier, Jean-Nicolas Audinot, David Gibouin, Tom Wirtz, Rabah Boukherroub, Henri-Noël Migeon, Aaron Bensimon, Laurent Jannière, Camille Ripoll, Victor Norris

Publikováno v: F1000Research, Vol 5 (2016)

Dynamic secondary ion mass spectrometry (D-SIMS) imaging of combed DNA – the combing, imaging by SIMS or CIS method – has been developed previously using a standard NanoSIMS 50 to reveal, on the 50 nm scale, individual DNA fibers labeled with dif

Externí odkaz: https://doaj.org/article/06afbbafed934cfe9a186200866d7457

Plant Accommodation to Their Environment: The Role of Specific Forms of Memory

Autor: Michel Thellier, Camille Ripoll, Ulrich Lüttge, Victor Norris

Publikováno v: Memory and Learning in Plants ISBN: 9783319755953

A plant germinates and becomes established in a particular place, which remains its permanent location and where it must respond to signals generated by the dynamics of all kinds of external conditions. By putting together old and new data originatin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fb82dcdec82e09f794598418ccdee96
https://doi.org/10.1007/978-3-319-75596-0_7

Hybolites Revisited

Autor: Victor Norris, Cecile Verrier, Marc Feuilloley

Publikováno v: recent patents on anti-infective drug discovery
recent patents on anti-infective drug discovery, 2016, 11, pp.16-31
recent patents on anti-infective drug discovery, 2016, 11 (1), pp.16-31. ⟨10.2174/1574891X11666160406121706⟩

International audience; Background: Hyperstructures are large assemblies of molecules and macro-molecules that perform functions such as metabolism (including RNA and protein synthesis and degradation), transport, DNA replication, cell division, sign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50e3a1c023c6bbb2b581aa1c658af66
https://hal-normandie-univ.archives-ouvertes.fr/hal-02352531

Identification and relative quantification of fatty acids in Escherichia coli membranes by gas chromatography/mass spectrometry

Autor: Catherine Lange, Delphine Oursel, Nicole Orange, Victor Norris, Sylvie Chevalier, Corinne Loutelier-Bourhis

Publikováno v: Rapid Communications in Mass Spectrometry. 21:3229-3233

The lipids that are essential to the functioning of the bacterial membrane exist in hundreds of different forms. The reasons for this diversity are far from clear but are presumably related to the roles of these lipids in both facilitating enzymic ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73a49a46e74cfe83820d8b0bf274f6eb
https://doi.org/10.1002/rcm.3177