Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Victor Mangas"'
Autor:
Karine Rodríguez-Fernández, Javier Zarzoso-Foj, Marina Saez-Bello, Almudena Mateu-Puchades, Antonio Martorell-Calatayud, Matilde Merino-Sanjuan, Elena Gras-Colomer, Monica Climente-Martí, Victor Mangas-Sanjuan
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1295 (2024)
Background/Objectives: Implementing model-informed precision dosing (MIPD) strategies guided by population pharmacokinetic/pharmacodynamic (PK/PD) models could enhance the management of inflammatory diseases such as psoriasis. However, the extent of
Externí odkaz:
https://doaj.org/article/ccfe46024c91474d8e2ad06b8f5c444d
Autor:
Aymara Sancho-Araiz, Zinnia P Parra-Guillen, Jean Bragard, Sergio Ardanza, Victor Mangas-Sanjuan, Iñaki F Trocóniz
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 10, p e1011507 (2023)
Mathematical modeling of unperturbed and perturbed tumor growth dynamics (TGD) in preclinical experiments provides an opportunity to establish translational frameworks. The most commonly used unperturbed tumor growth models (i.e. linear, exponential,
Externí odkaz:
https://doaj.org/article/83e6686c29df4c62b1781b73a62be77b
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/e7e705416efb483f8c466d596773db0b
Autor:
Teresa García-Martínez, María Dolores Bellés-Medall, Maria García-Cremades, Raúl Ferrando-Piqueres, Victor Mangas-Sanjuán, Matilde Merino-Sanjuan
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2226 (2022)
The aims of this study are (i) to develop a population pharmacokinetic/pharmacodynamic model of daptomycin in patients with normal and impaired renal function, and (ii) to establish the optimal dose recommendation of daptomycin in clinical practice.
Externí odkaz:
https://doaj.org/article/a33003171f6e4b1985309b4c7300e068
Autor:
Mark McAllister, Talia Flanagan, Susan Cole, Andreas Abend, Evangelos Kotzagiorgis, Jobst Limberg, Heather Mead, Victor Mangas-Sanjuan, Paul A. Dickinson, Andrea Moir, Xavier Pepin, Diansong Zhou, Christophe Tistaert, Aristides Dokoumetzidis, Om Anand, Maxime Le Merdy, David B. Turner, Brendan T. Griffin, Adam Darwich, Jennifer Dressman, Claire Mackie
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 1010 (2022)
A webinar series that was organised by the Academy of Pharmaceutical Sciences Biopharmaceutics focus group in 2021 focused on the challenges of developing clinically relevant dissolution specifications (CRDSs) for oral drug products. Industrial scien
Externí odkaz:
https://doaj.org/article/ef6f2c994c1b4a04809bf2645feb40a0
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 1016 (2021)
Immuno-oncology (IO) focuses on the ability of the immune system to detect and eliminate cancer cells. Since the approval of the first immune checkpoint inhibitor, immunotherapies have become a major player in oncology treatment and, in 2021, represe
Externí odkaz:
https://doaj.org/article/9bfbb8fa44d2462d8afe34977b812c1d
Autor:
Francisco José Toja-Camba, Nerea Gesto-Antelo, Olalla Maroñas, Eduardo Echarri Arrieta, Irene Zarra-Ferro, Miguel González-Barcia, Enrique Bandín-Vilar, Victor Mangas Sanjuan, Fernando Facal, Manuel Arrojo Romero, Angel Carracedo, Cristina Mondelo-García, Anxo Fernández-Ferreiro
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 935 (2021)
Over the last two decades, pharmacogenetics and pharmacokinetics have been increasingly used in clinical practice in Psychiatry due to the high variability regarding response and side effects of antipsychotic drugs. Specifically, long-acting injectab
Externí odkaz:
https://doaj.org/article/26dcb4bb4a95444aabe52153bd23ef56
Autor:
Darlene Santiago, Victor Mangas-Sanjuan, Kyle Melin, Jorge Duconge, Wenchen Zhao, Raman Venkataramanan
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1226 (2020)
Background: The aim of this analysis was to characterize the pharmacokinetics (PK) of sublingual buprenorphine (BUP) and its metabolites (buprenorphine glucuronide; BUP-g, norbuprenorphine; Nor-BUP, and norbuprenorphine glucuronide; Nor-BUP-g) in opi
Externí odkaz:
https://doaj.org/article/10148acac061492e9ba7132c0d27d44c
Autor:
Javier Reig-López, María del Mar Maldonado, Matilde Merino-Sanjuan, Ailed M. Cruz-Collazo, Jean F. Ruiz-Calderón, Victor Mangas-Sanjuán, Suranganie Dharmawardhane, Jorge Duconge
Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 975 (2020)
MBQ-167 is a dual inhibitor of the Rho GTPases Rac and Cdc42 that has shown promising results as an anti-cancer therapeutic at the preclinical stage. This drug has been tested in vitro and in vivo in metastatic breast cancer mouse models. The aim of
Externí odkaz:
https://doaj.org/article/5a76ba2dc99e411cbf4933a69f59f030
Autor:
Javier Reig‐Lopez, Weifeng Tang, Carlos Fernandez‐Teruel, Matilde Merino‐Sanjuan, Victor Mangas‐Sanjuan, David W. Boulton, Pradeep Sharma
Publikováno v:
British Journal of Clinical Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::130f0dcd7b60874d9d094a2b7f8629fa
https://doi.org/10.1111/bcp.15745
https://doi.org/10.1111/bcp.15745