Increased plasma norepinephrine concentration in psychotic depression

Autor: Godfried M.J. Van Kempen, Jaap G. Goekoop, Remco F.P. de Winter, Victor M. Wiegant, Ron Wolterbeek

Publikováno v: Therapeutic Advances in Psychopharmacology. 2:51-63

Objective: We previously found psychotic depression (PSDEP) to have positively correlating plasma norepinephrine (NE) and vasopressin (AVP) concentrations. Since central noradrenergic activity and plasma NE concentration are highly correlated, this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15a80da17a2ec185d97d284b7202258
https://doi.org/10.1177/2045125312436574

Spatial learning in pigs: effects of environmental enrichment and individual characteristics on behaviour and performance

Autor: Berry M. Spruijt, Jarno Jansen, Willem G.P. Schouten, Victor M. Wiegant, J. Elizabeth Bolhuis

Publikováno v: Animal Cognition, 12(2), 303-315
Animal Cognition, 12, 303-315
Animal Cognition 12 (2009) 2
Animal Cognition, 12, 2, pp. 303-315

Contains fulltext : 77372.pdf (Publisher’s version ) (Closed access) This study investigated the effects of both environmental enrichment and individual behavioural characteristics on spatial cognitive capabilities of pigs, using a novel latent spa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edb87a6f9070d5d12eedc24acf23d68
https://doi.org/10.1007/s10071-008-0191-y

Individual reactivity to the open-field predicts the expression of stress-induced behavioural and somatic pain sensitisation

Autor: Rianne Stam, Victor M. Wiegant, Léon van Gurp, Gert-Jan Geerse

Publikováno v: Behavioural Brain Research. 174:112-118

Posttraumatic stress disorder (PTSD) is the fourth most common psychiatric disorder. It is associated with somatic complaints like pain problems. Only a proportion of persons exposed to traumatic events develop PTSD. Several factors, like genetic pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd0261203f4cfbb4d87470fdcf1494a
https://doi.org/10.1016/j.bbr.2006.07.010

Stress, Depression and Hippocampal Apoptosis

Autor: E. Ron de Kloet, Dick F. Swaab, Vivi M. Heine, Paul J. Lucassen, Eline M. van der Beek, Eberhard Fuchs, Boldizsár Czéh, Marian Joëls, Marianne B. Müller, Victor M. Wiegant

Publikováno v: Lucassen, P J, Heine, V M, Muller, M B, van der Beek, E M, Wiegant, V M, De Kloet, E R, Joels, M, Fuchs, E, Swaab, D F & Czeh, B 2006, ' Stress, depression and hippocampal apoptosis ', CNS and Neurological Disorders. Drug Targets, vol. 5, no. 5, pp. 531-46 . https://doi.org/10.2174/187152706778559273

In this review, we summarize and discuss recent studies on structural plasticity changes, particularly apoptosis, in the mammalian hippocampus in relation to stress and depression. Apoptosis continues to occur, yet with very low numbers, in the adult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063b5c40bd08f9846b3a9d045e58860f
https://doi.org/10.2174/187152706778559273

Differential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event

Autor: Victor M. Wiegant, Martien J H Kas, Roger A.H. Adan, Adrie W. Bruijnzeel, Jurgen R. Haanstra

Publikováno v: Journal of Molecular Endocrinology. 35:159-164

Stress affects eating behaviour in rodents and humans, suggesting that the regulation of energy balance and the stress response are coupled physiological processes. Neuropeptide Y (NPY) and agouti-related protein (AgRP) are potent food-stimulating ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3924c43f2e9c7a5bf31bfce6648274
https://doi.org/10.1677/jme.1.01819