Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Victor M Karpyak"'
Autor:
Tyler S. Oesterle, MD, MPH, Daniel K. Hall-Flavin, MD, MS, Nicholas L. Bormann, MD, Larissa L. Loukianova, MD, PhD, David C. Fipps, DO, Scott A. Breitinger, MD, Wesley P. Gilliam, PhD, Tiffany Wu, MD, Sabrina Correa da Costa, MD, Stephan Arndt, PhD, Victor M. Karpyak, MD, PhD
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 2, Pp 192-206 (2024)
Mobile phone applications (MPAs) for substance use disorder (SUD) treatment are increasingly used by patients. Although pilot studies have shown promising results, multiple previous systematic reviews noted insufficient evidence for MPA use in SUD tr
Externí odkaz:
https://doaj.org/article/6926b0bfced545efa5b6e929f690d318
Autor:
Ming-Fen Ho, Cheng Zhang, Irene Moon, Mustafa Tuncturk, Brandon J. Coombes, Joanna Biernacka, Michelle Skime, Tyler S. Oesterle, Victor M. Karpyak, Hu Li, Richard Weinshilboum
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Alcohol use disorder (AUD) is the most prevalent substance use disorder worldwide. Acamprosate and naltrexone are anti-craving drugs used in AUD pharmacotherapy. However, molecular mechanisms underlying their anti-craving effect remain uncle
Externí odkaz:
https://doaj.org/article/733ec22160cf45808418177567760984
Autor:
Joanna M Biernacka, Jennifer R Geske, Terry D Schneekloth, Mark A Frye, Julie M Cunningham, Doo-Sup Choi, Courtney L Tapp, Bradley R Lewis, Maureen S Drews, Tracy L Pietrzak, Colin L Colby, Daniel K Hall-Flavin, Larissa L Loukianova, John A Heit, David A Mrazek, Victor M Karpyak
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58798 (2013)
Genome-wide association studies (GWAS) have revealed many single nucleotide polymorphisms (SNPs) associated with complex traits. Although these studies frequently fail to identify statistically significant associations, the top association signals fr
Externí odkaz:
https://doaj.org/article/7315c35d8e4f46f19c95067765fbf8f7
Autor:
Ulrich W Preuss, Stacey J Winham, Joanna M Biernacka, Jennifer R Geske, Georgy Bakalkin, Gabriele Koller, Peter Zill, Michael Soyka, Victor M Karpyak
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78688 (2013)
One of the proposed psychobiological pathways of craving attributes the desire for drinking in the context of tension, discomfort or unpleasant emotions, to "negative" (or "relief") craving. The aim of this study was to replicate a previously reporte
Externí odkaz:
https://doaj.org/article/8e009f94c7424e46b1aadf528a6ae3d2
Autor:
Jeong-Hyun Kim, Victor M Karpyak, Joanna M Biernacka, Hyung Wook Nam, Moonnoh R Lee, Ulrich W Preuss, Peter Zill, Gihyun Yoon, Colin Colby, David A Mrazek, Doo-Sup Choi
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16331 (2011)
Adenosine is involved in several neurological and behavioral disorders including alcoholism. In cultured cell and animal studies, type 1 equilibrative nucleoside transporter (ENT1, slc29a1), which regulates adenosine levels, is known to regulate etha
Externí odkaz:
https://doaj.org/article/cf50ba33b545456389140e858a51d515
Autor:
Ming-Fen Ho, Cheng Zhang, Irene Moon, Joanna Biernacka, Brandon Coombes, Quyen Ngo, Cedric Skillon, Michelle Skime, Tyler Oesterle, Paul E. Croarkin, Victor M. Karpyak, Hu Li, Richard M. Weinshilboum
Publikováno v:
Molecular Metabolism, Vol 77, Iss , Pp 101798- (2023)
Objective: Fibroblast growth factor 21 (FGF21) analogs have been tested as potential therapeutics for substance use disorders. Prior research suggests that FGF21 administration might affect alcohol consumption and reward behaviors. Our recent report
Externí odkaz:
https://doaj.org/article/9844a113c6ba4872bd423d7d243c3cf0
Autor:
Terry D. Schneekloth, MD, Juan P. Arab, MD, Douglas A. Simonetto, MD, Tanya M. Petterson, MS, Shehzad K. Niazi, MD, Daniel K. Hall-Flavin, MD, PhD, Victor M. Karpyak, MD, PhD, Bhanu P. Kolla, MD, James E. Roth, MD, Walter K. Kremers, PhD, Charles B. Rosen, MD
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 5, Iss 6, Pp 1153-1164 (2021)
Objective: To assess the impact of standardized pretransplant alcohol abstinence and treatment guidelines on liver transplant outcomes. Methods: This study assessed the posttransplant relapse and survival associated with a pretransplant guideline man
Externí odkaz:
https://doaj.org/article/7832cccb46d4443f8812fb2fd169fc12
Autor:
Bhanu Prakash Kolla, Stacey J Winham, Ada Man-Choi Ho, Meghna P Mansukhani, Larissa L Loukianova, Vanessa Pazdernik, Victor M Karpyak
Publikováno v:
Alcohol and Alcoholism. 58:209-215
AimsBrain-derived neurotrophic factor (BDNF) levels may be associated with alcohol use disorders (AUD) and alcohol consumption, correlate with sleep disturbance and be influenced by sex differences and sex hormones. These associations have not been e
Autor:
David J. Hinton, Marely Santiago Vázquez, Jennifer R. Geske, Mario J. Hitschfeld, Ada M. C. Ho, Victor M. Karpyak, Joanna M. Biernacka, Doo-Sup Choi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Precision medicine for alcohol use disorder (AUD) allows optimal treatment of the right patient with the right drug at the right time. Here, we generated multivariable models incorporating clinical information and serum metabolite levels to
Externí odkaz:
https://doaj.org/article/d17a8ba0a08e49ca9953eacbb578a883
Autor:
Tyler S. Oesterle, Victor M. Karpyak, Brandon J. Coombes, Arjun P. Athreya, Scott A. Breitinger, Sabrina Correa da Costa, Danielle J. (Dana) Gerberi
Publikováno v:
The American Journal on Addictions. 31:535-545
Substance use disorders (SUDs) are chronic relapsing diseases characterized by significant morbidity and mortality. Phenomenologically, patients with SUDs present with a repeating cycle of intoxication, withdrawal, and craving, significantly impactin