Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Victor L. Boyartchuk"'
Publikováno v:
Infection and Immunity. 79:1526-1535
Host cells use metabolic signaling through the LXRα nuclear receptor to defend against Listeria monocytogenes infection. 25-Hydroxycholesterol is a natural ligand of LXRs that is produced by the enzyme cholesterol 25-hydroxylase (CH25H). We found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8341caa1b803e3255ff2b2b670aabc70
https://doi.org/10.1128/iai.01195-10
https://doi.org/10.1128/iai.01195-10
Autor:
Oleg Garifulin, Haihong Shen, Zanmei Qi, Michael R. Green, Sujatha Patnala, Victor L. Boyartchuk
Publikováno v:
PLoS Genetics, Vol 3, Iss 9, Pp 1587-1597 (2007)
PLoS Genetics
PLoS Genetics
Genetic makeup of the host plays a significant role in the course and outcome of infection. Inbred strains of mice display a wide range of sensitivities to Listeria monocytogenes infection and thus serve as a good model for analysis of the effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd12d2f7bc401f0630c474de035a725f
http://europepmc.org/articles/PMC1971118?pdf=render
http://europepmc.org/articles/PMC1971118?pdf=render
Autor:
Nancy C. Andrews, Jerry Kaplan, Victor L. Boyartchuk, Prasad N. Paradkar, Mark D. Fleming, Diane M. Ward, Fudi Wang, Kristina A. Roberts, Angel O. Custodio, Dean R. Campagna, William F. Dietrich
Publikováno v:
Nature Genetics. 39:1025-1032
We undertook a quantitative trait locus (QTL) analysis in mice to identify modifier genes that might influence the severity of human iron disorders. We identified a strong QTL on mouse chromosome 9 that differentially affected macrophage iron burden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6763cf6c98d90ec9396778b994038fcb
https://doi.org/10.1038/ng2059
https://doi.org/10.1038/ng2059
Autor:
Oleg Garifulin, Victor L. Boyartchuk
Publikováno v:
Briefings in Functional Genomics and Proteomics. 4:258-269
For almost half a century, the mouse model of Listeria monocytogenes infection has been used to analyse both innate and adaptive components of immunity and to discover key immune genes. Vast accumulated knowledge about the disease in mice provides a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4346fad11ad47629730799c45f165a
https://doi.org/10.1093/bfgp/4.3.258
https://doi.org/10.1093/bfgp/4.3.258
Autor:
Mathias Müller, Victor L. Boyartchuk, Sandy W. Wong, George S. Yap, William F. Dietrich, Josiane Ragimbeau, Michael H. Shaw, Sandra Pellegrini, Marina Karaghiosoff
Publikováno v:
Proceedings of the National Academy of Sciences. 100:11594-11599
The B10.Q/J strain of mice was serendipitously discovered to be highly susceptible to infection by the intracellular protozoan parasite,Toxoplasma gondiibut markedly resistant to induction of autoimmune arthritis. We have previously shown that the B1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f919de360eb4c1881e3baadbdcd61d
https://doi.org/10.1073/pnas.1930781100
https://doi.org/10.1073/pnas.1930781100
Publikováno v:
Genetics. 161:509-519
Spt3 of Saccharomyces cerevisiae is required for the normal transcription of many genes in vivo. Past studies have shown that Spt3 is required for both mating and sporulation, two events that initiate when cells are at G1/START. We now show that Spt3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf260d5369e687c20bbfd3df4950d929
https://doi.org/10.1093/genetics/161.2.509
https://doi.org/10.1093/genetics/161.2.509
Publikováno v:
Current Biology. 11(19):1503-1511
Background: Inbred mouse strains exhibit striking differences in the susceptibility of their macrophages to the effects of anthrax lethal toxin (LeTx). Previous data has shown that this difference in susceptibility lies downstream of toxin entry into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900f506dc725cc9c167d23d802aea8f2
Autor:
David B. Rozema, C. Dale Poulter, Victor L. Boyartchuk, Jasper Rine, Elizabeth A. Picologlou, C E Trueblood
Publikováno v:
Molecular and Cellular Biology. 20:4381-4392
Many proteins that contain a carboxyl-terminal CaaX sequence motif, including Ras and yeast a-factor, undergo a series of sequential posttranslational processing steps. Following the initial prenylation of the cysteine, the three C-terminal amino aci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca01ee3410128b167bc06d4746fadb9a
https://doi.org/10.1128/mcb.20.12.4381-4392.2000
https://doi.org/10.1128/mcb.20.12.4381-4392.2000
Autor:
Victor L. Boyartchuk, Jasper Rine
Publikováno v:
Genetics. 150:95-101
In eukaryotes small secreted peptides are often proteolytically cleaved from larger precursors. In Saccharomyces cerevisiae multiple proteolytic processing steps are required for production of mature 12-amino-acid a-factor from its 36-amino-acid prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fa6f52b9b3599be831fc416bc08fae
https://doi.org/10.1093/genetics/150.1.95
https://doi.org/10.1093/genetics/150.1.95
Publikováno v:
Proceedings of the National Academy of Sciences. 94:10774-10779
Protein prenyltransferases catalyze the covalent attachment of isoprenoid lipids (farnesyl or geranylgeranyl) to a cysteine near the C terminus of their substrates. This study explored the specificity determinants for interactions between the farnesy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e9d006f25c1513a3b3e514c9800de4
https://doi.org/10.1073/pnas.94.20.10774
https://doi.org/10.1073/pnas.94.20.10774