Zobrazeno 1 - 10
of 273
pro vyhledávání: '"Victor J. Marder"'
Since publication of the First Edition in 1982, Hemostasis and Thrombosis has established itself as the pre-eminent book in the field of coagulation disorders. No other book is as inclusive in scope, with coverage of the field from the standpoint of
Autor:
Victor J. Marder, Marc Ribó, Peter Mitchell, Kecia L. Courtney, Jeffrey L. Saver, Bernard Yan, Miroslav Brozman
Publikováno v:
Journal of Stroke and Cerebrovascular Diseases. 26:308-320
Background This phase 1/2a, open-label, multicenter, dose-escalation, safety study describes the first evaluation of plasmin as an intracranial thrombolytic treatment for acute ischemic stroke in the middle cerebral artery. The rationale for intrathr
Autor:
Benjamin Kim, Victor J. Marder, Zachary A. Hing, Zuben E. Sauna, Eric J. Broxham, Chava Kimchi-Sarfaty, David Liuwantara, Pamela Kempert, Tal Schiller, Tom E. Howard, Nathan C. Edwards, Vijaya L. Simhadri, Andrew Wu, Evi B. Struble
Publikováno v:
British Journal of Haematology. 165:154-158
Background Although autosomal recessive hematologic disorders are individually rare and difficult to ascertain, studies involving one or more homozygous affected children and their unaffected heterozygous parents have led to expanded understanding of
Autor:
Ellis J. Neufeld, Susan F. Assmann, Joan Cox Gill, Marcela Torres, Catherine S. Manno, Nigel S. Key, Leslie Raffini, Victor J. Marder, Cindy A. Leissinger, Janna M. Journeycake, Cassandra D. Josephson, Rebecca Kruse-Jarres, Barbara A. Konkle, Carolyn M. Bennett, Margaret V. Ragni, Keith R. McCrae, Leonard A. Valentino, Kapil Saxena, Suzanne Granger
Publikováno v:
Thrombosis and Haemostasis. 112:445-458
SummaryThe development of antibodies against infused factor VIII (FVIII) in patients with haemophilia A is a serious complication leading to poorly controlled bleeding and increased morbidity. No treatment has been proven to reduce high titre antibod
Publikováno v:
American Journal of Hematology. 90:561-563
Autor:
Richard D. Shlansky-Goldberg, Chunqin Deng, Victor J. Marder, J. P. Davis, Kim Hanna, David Fineberg, Anthony J. Comerota
Publikováno v:
Journal of Thrombosis and Haemostasis. 10:985-991
Summary. Background: Current treatment of acute peripheral artery or bypass graft occlusion utilizes catheter-directed thrombolysis of a plasminogen activator (PA). Plasmin is a direct-acting thrombolytic with a striking safety advantage over PA in p
Autor:
Job Harenberg, Victor J. Marder, Martin Wehling, Svetlana Marx, Ola E. Dahl, Christel Weiss, Astrid Schulze
Publikováno v:
Thrombosis and Haemostasis. 108:903-912
SummaryNew oral anticoagulant (NOAC) regimens [dabigatran 150 mg (D150) and 220 mg (D220), rivaroxaban 10 mg (R20), and apixaban 2.5 mg bid (A5)] were effective and safe compared to enoxaparin for the prevention of venous thromboembolism (VTE) follow
Autor:
Shuo Liu, Victor J. Marder, David E. Levy, Annlia Paganini-Hill, Mark Fisher, Shur-Jen Wang, Fan Yang
Publikováno v:
Stroke. 42:3277-3280
Background and Purpose— Ancrod, derived from Malayan pit viper venom, has been tested as ischemic stroke treatment in clinical trials with inconsistent results. We studied the actions of ancrod on fibrinolysis pathways in patient plasma samples and
Autor:
Reza Jahan, Theresa Gruber, Aleš Blinc, Gregor Tratar, Victor J. Marder, Gary Duckwiler, Doojin Kim, David S Liebeskind, Paul M. Vespa, Sidney Starkman, Fernando Vinuela, Bruce Ovbiagele, Satoshi Tateshima, Jeffrey L. Saver, Nestor R Gonzalez, Mišo Šabovič, Letisha Ali
Publikováno v:
Stroke. 42:2222-2228
Background and Purpose— Plasmin is a direct-acting thrombolytic with a better safety profile than recombinant tissue-type plasminogen activator (rtPA) in animal models. With the application of retrieval devices for managing acute ischemic stroke, e
Autor:
Victor J. Marder
Publikováno v:
Thrombosis Research. 123:S56-S61
Plasmin is the prototype of a distinct class of "direct-acting" fibrinolytic agents, with biochemical and physiological attributes that are favorable for catheter-delivered thrombolytic therapy. Our studies indicate that plasmin is superior to plasmi