Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Victor J. DeNoble"'
Autor:
Victor J. Denoble, Paul C. Mele
Publikováno v:
Psychopharmacology. 184:266-272
The rate and pattern of lever pressing were studied in 18 rats during 24-h sessions in which responding resulted in intravenous infusions of nicotine. There were four indications of the positive reinforcing effect of nicotine: (1) a greater number of
Publikováno v:
European Journal of Pharmacology. 179:97-102
Several phencyclidine (PCP) and sigma receptor ligands were examined for their effects on a single trial passive avoidance test in rats. Rats were administered the PCP receptor ligands (+)-5-methyl-10,11-dihydro-5Hdibenzo[a,d]cyclohepten-5,10-im ine
Autor:
Leonard Cook, Victor J. Nickolson, George F. Steinfels, Victor J. DeNoble, Kenneth W. Rohrbach
Publikováno v:
Drug Development Research. 19:301-314
DuP 996, 3,3,-Bis(4-pyridinylmethyl)-1-phenylindolin-2-one, a potent in vitro and in vivo releaser of acetylcholine (ACh), dopamine (DA), and serotonin (5HT) in rat brain, significantly enhanced the performance of rats and mice in several behavioral
Publikováno v:
European Journal of Pharmacology. 175:197-202
3-((+-)-2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP), phencyclidine (PCP) and diazepam were evaluated for their ability to produce a deficit for a single trial step-through passive avoidance response in rats. Pretraining administration with
Autor:
Pieter B.M.W.M. Timmermans, Kimi F. DeNoble, Karen R. Spencer, Pancras C. Wong, Andrew T. Chiu, Victor J. DeNoble
Publikováno v:
Brain research. 561(2)
Non-peptide receptor ligands with differential affinity for the angiotensin II-1 (AII-1) receptor (EXP3312, EXP3880) or the AII-2 receptor (PD123177) and an angiotensin converting enzyme (ACE) inhibitor captopril were evaluated for the ability to pro
Publikováno v:
Pharmacology, biochemistry, and behavior. 39(4)
Cognitive deficits resulting from neuropathological brain changes such as Alzheimer's Disease or normal aging are most likely due to alterations in multiple neurotransmitter systems. While the majority of preclinical studies have focused on the effec
Publikováno v:
Brain research bulletin. 26(5)
DuP 996 and ketanserin have previously been shown to protect against experimentally induced passive avoidance (PA) deficits. In the present experiment the potential interaction between DuP 996 and ketanserin on hypoxia-induced amnesia was evaluated.
Autor:
Leonard Cook, M.J. Myers, Karen R. Spencer, Victor J. DeNoble, Kimi F. DeNoble, L.C. Johnson, R.M. Scribner
Publikováno v:
Pharmacology, biochemistry, and behavior. 36(4)
DuP 996, 3,3-bis(4-pyrindinylmethyl)-1-phenylindolin-2-one, physostigmine (PH), tetrahydroaminoacridine (THA) and 3,4-diaminopyridine (3,4-DAP) were compared for their ability to protect against hypoxia-induced performance deficits in a passive avoid
Publikováno v:
Pharmacology Biochemistry and Behavior. 16:113-117
The number of liquid deliveries and pattern of concurrent pentobarbital and water drinking were studied in three food deprived rhesus monkeys during daily 3-hr sessions. During the daily sessions, deliveries of approximately 0.6 ml of each liquid occ
Publikováno v:
Psychopharmacology. 77:317-321
The behavioral effects of intraventricularly (IVT) administered (-)-nicotine on food-maintained behavior were studied. Rats responded by pressing a lever under various fixed ratio (FR) schedules. Infusion of 5 microgram of (-)-nicotine suppressed res