Výsledky vyhledávání - "Victor J Johnson"

Akademický článek

Application and interpretation of immunophenotyping data in safety and risk assessment

Autor: Victor J. Johnson, Michael I. Luster, Andrew Maier, Corey Boles, Eric W. Miller, Daniel E. Arrieta

Publikováno v: Frontiers in Toxicology, Vol 6 (2024)

The use of immunophenotyping during immunotoxicity investigations was first popularized in the 1980 s and has since become more integrated into diagnostic and non-clinical assessments. The data provided from immunophenotyping can serve as an initial

Externí odkaz: https://doaj.org/article/58a0deb4a7c44cb28b90cc78afe0dfaa

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Akademický článek

Leucine-rich repeat kinase 2 (LRRK2)-deficient rats exhibit renal tubule injury and perturbations in metabolic and immunological homeostasis.

Autor: Daniel Ness, Zhao Ren, Shyra Gardai, Douglas Sharpnack, Victor J Johnson, Richard J Brennan, Elizabeth F Brigham, Andrew J Olaharski

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e66164 (2013)

Genetic evidence links mutations in the LRRK2 gene with an increased risk of Parkinson's disease, for which no neuroprotective or neurorestorative therapies currently exist. While the role of LRRK2 in normal cellular function has yet to be fully desc

Externí odkaz: https://doaj.org/article/0e92e327929b407982215728de1da048

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Evaluation of skin sensitization induced by four ionic liquids

Autor: Shawn F. Harris, Wimolnut Manheng, Kimber L. White, Travis Gulledge, Kristen Ryan, Dori R. Germolec, Michelle J. Hooth, Victor J. Johnson, Rachel P. Frawley, Keith R. Shockley

Publikováno v: Journal of Applied Toxicology. 42:392-408

Ionic liquids (ILs) are synthetic solvents used as replacements for volatile organic solvents. Human exposure occurs through dermal or oral routes. In rodents, several ILs were reported to induce dermal toxicity, irritation, and sensitization. Due to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938b2ecd2121c1e95017dc298b83efc4
https://doi.org/10.1002/jat.4224

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Immunotoxicity studies of sulfolane following developmental exposure in Hsd:Sprague Dawley SD rats and adult exposure in B6C3F1/N mice

Autor: Keith R. Shockley, Barney Sparrow, Victor J. Johnson, Matt D. Stout, Chad R. Blystone, Gary R. Burleson, Dawn Fallacara, Michael I. Luster, Dori R. Germolec, Mark F. Cesta, Michelle C. Cora, AtLee T. D. Watson

Publikováno v: Journal of Immunotoxicology, Vol 18, Iss 1, Pp 1-12 (2021)
Journal of immunotoxicology

Sulfolane is a solvent used in the petrochemical industry and a groundwater contaminant in areas near refineries. The current studies were conducted to assess the impact of oral exposure to sulfolane on the immune system using two models: (1) a perin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b980ec7e4967fc4971f63f8118940bce
https://doaj.org/article/dedc6a16c38a4f61826536e8e9921adf

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Leveraging information technology literacy to enhance college and career readiness for secondary students with disabilities

Autor: Victor J. Johnson, Margo Vreeburg Izzo, Yan Wei, Andrew Buck, Jennifer Kowitt, Jay Hsiao, Nicholas W. Gelbar, Allison Lombardi, Alexa Murray

Publikováno v: Journal of Vocational Rehabilitation. 46:389-397

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0571edc3a6a29c9cb81e5a60ec7d6418
https://doi.org/10.3233/jvr-170875

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A Preliminary Psychometric Analysis of a Measure of Information Technology Literacy Skills

Autor: Victor J. Johnson, Andrew Buck, Alexa Murray, Allison Lombardi, Margo Vreeburg Izzo, Graham G. Rifenbark

Publikováno v: Career Development and Transition for Exceptional Individuals. 40:235-243

Information technology (IT) literacy skills are increasingly important for all adolescents to learn, as the majority of post-school pursuits will require at least some amount of computer skills. For adolescents with disabilities, this urgency is perh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c3e6ed6cadc7ff1002fadf906245347
https://doi.org/10.1177/2165143416682476

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Host Resistance Assays

Autor: Stefanie C M, Burleson, Wendy Jo, Freebern, Florence G, Burleson, Gary R, Burleson, Victor J, Johnson, Robert W, Luebke

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1803

The goal of immunotoxicity testing is to obtain data useful for immunotoxicity safety assessment. Guidance in the performance of immunotoxicity safety evaluations is provided in documents from the US EPA for chemicals and the ICH S8 document for phar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::410f6bb560fdc2c87ac50823180d02bf
https://pubmed.ncbi.nlm.nih.gov/29882137

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Host Resistance Assays

Autor: Florence G. Burleson, Robert W. Luebke, Victor J. Johnson, Stefanie C.M. Burleson, Gary R. Burleson, Wendy J. Freebern

Publikováno v: Methods in Molecular Biology ISBN: 9781493985487

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cce4b2ab7186dc8240dfd3369c37ec04
https://doi.org/10.1007/978-1-4939-8549-4_9

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Hypersensitivity Reactions in the Respiratory Tract

Autor: Victor J. Johnson, Stefanie C.M. Burleson

Chemicals and proteins can cause hypersensitivity reactions in the respiratory tract via multiple mechanisms. Hypersensitivity responses require a latency period and develop in two stages: An induction or sensitization phase, during which the immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94a99e4a4b82203e7d8b8fee7c210fb4
https://doi.org/10.1016/b978-0-12-801238-3.95633-2

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