Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Victor I. Spoormaker"'
Autor:
Andy Brendler, Max Schneider, Immanuel G. Elbau, Rui Sun, Taechawidd Nantawisarakul, Dorothee Pöhlchen, Tanja Brückl, BeCOME Working Group, Michael Czisch, Philipp G. Sämann, Michael D. Lee, Victor I. Spoormaker
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Major depressive disorder (MDD) is a devastating and heterogenous disorder for which there are no approved biomarkers in clinical practice. We recently identified anticipatory hypo-arousal indexed by pupil responses as a candidate mechanism
Externí odkaz:
https://doaj.org/article/bc3d2bcc23344e8e9b6884656ee4aeab
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Specific phobias are the most common anxiety disorder and are characterized by avoidance behavior. Avoidance behavior impacts daily function and is proposed to impair extinction learning. However, despite its prevalence, its objective assessment rema
Externí odkaz:
https://doaj.org/article/451b6807008c47009026cfed09efe059
Autor:
Tanja M. Brückl, Victor I. Spoormaker, Philipp G. Sämann, Anna-Katharine Brem, Lara Henco, Darina Czamara, Immanuel Elbau, Norma C. Grandi, Lee Jollans, Anne Kühnel, Laura Leuchs, Dorothee Pöhlchen, Maximilian Schneider, Alina Tontsch, Martin E. Keck, Leonhard Schilbach, Michael Czisch, Susanne Lucae, Angelika Erhardt, Elisabeth B. Binder
Publikováno v:
BMC Psychiatry, Vol 20, Iss 1, Pp 1-25 (2020)
Abstract Background A major research finding in the field of Biological Psychiatry is that symptom-based categories of mental disorders map poorly onto dysfunctions in brain circuits or neurobiological pathways. Many of the identified (neuro) biologi
Externí odkaz:
https://doaj.org/article/50af342dc0eb4d89bd4eeae5fa7fd1c9
Autor:
Dorothee Pöhlchen, Marthe Priouret, Miriam S. Kraft, Florian P. Binder, Deniz A. Gürsel, Götz Berberich, BeCOME working group, Kathrin Koch, Victor I. Spoormaker, E. B. Binder, T. M. Brückl, M. Czisch, A. Erhardt, N. C. Grandi, S. Lucae, P. Sämann, A. Tontsch, I.A. von Muecke-Heim, J. Ziebula
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Obsessive-compulsive disorder (OCD) is characterized by recurrent, persistent thoughts and repetitive behaviors causing stress and anxiety. In the associative learning model of OCD, mechanisms of fear extinction are supposed to partly underlie sympto
Externí odkaz:
https://doaj.org/article/0e4a1bafefd341508a2ca6d47f6998a4
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Avoidance behavior is a key symptom of most anxiety disorders and a central readout in animal research. However, the quantification of real-life avoidance behavior in humans is typically restricted to clinical populations, who show actual avoidance o
Externí odkaz:
https://doaj.org/article/836cea9dc6064a26900423567c3d9d81
Publikováno v:
Frontiers in Human Neuroscience, Vol 13 (2019)
Real-world memories involve the integration of multiple events across time, yet the mechanisms underlying this integration is unknown. Recent rodent studies show that distinct memories encoded within a few hours, but not several days, share a common
Externí odkaz:
https://doaj.org/article/cec5a5875e814ccc9fe175c7f77faf4c
Autor:
Max Schneider, Immanuel G. Elbau, Teachawidd Nantawisarakul, Dorothee Pöhlchen, Tanja Brückl, BeCOME Working Group, Michael Czisch, Philipp G. Saemann, Michael D. Lee, Elisabeth B. Binder, Victor I. Spoormaker
Publikováno v:
Brain Sciences, Vol 10, Iss 12, p 906 (2020)
Depression is a debilitating disorder with high prevalence and socioeconomic cost, but the brain-physiological processes that are altered during depressive states are not well understood. Here, we build on recent findings in macaques that indicate a
Externí odkaz:
https://doaj.org/article/90ffb320c3734debb816e5518aca090d
Autor:
Michael Czisch, Philipp G. Sämann, Victor I. Spoormaker, Dorothee Pöhlchen, Julia Fietz, Florian P. Binder
Publikováno v:
Human Brain Mapping
The diameter of the human pupil tracks working memory processing and is associated with activity in the frontoparietal network. At the same time, recent neuroimaging research has linked human pupil fluctuations to activity in the salience network. In
Autor:
Anna-Katherine Brem, Martin E. Keck, Maximilian Schneider, Tanja Brückl, Laura Leuchs, Norma Christine Grandi, Lee Jollans, Alina Tontsch, Philipp G. Sämann, Anne Kühnel, Dorothee Pöhlchen, Darina Czamara, Angelika Erhardt, Immanuel Elbau, Lara Henco, Elisabeth B. Binder, Victor I. Spoormaker, Susanne Lucae, Michael Czisch, Leonhard Schilbach
Publikováno v:
BMC Psychiatry, Vol 20, Iss 1, Pp 1-25 (2020)
BMC Psychiatry
BMC Psychiatry
Background A major research finding in the field of Biological Psychiatry is that symptom-based categories of mental disorders map poorly onto dysfunctions in brain circuits or neurobiological pathways. Many of the identified (neuro) biological dysfu
Autor:
Dorothee Pöhlchen, Julia Fietz, Michael Czisch, Philipp G. Sämann, Victor I. Spoormaker, E.B. Binder, T.M. Brückl, A. Erhardt, N.C. Grandi, S. Lucae, I.A. von Muecke-Heim, J. Ziebula
Publikováno v:
Biological psychiatry. Cognitive neuroscience and neuroimaging.
Fear-related disorders are characterized by hyperexcitability in reflexive circuits and maladaptive associative learning mechanisms. The startle reflex is suited to investigate both processes, either by probing it under baseline conditions or by deri