Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Victor I, Seledtsov"'
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1160 (2022)
Cellular senescence is conditioned through two interrelated processes, i.e., a reduction in adenosine triphosphate (ATP) and the enhancement of reactive oxygen species (ROS) production levels in mitochondria. ATP shortages primarily influence the ene
Externí odkaz:
https://doaj.org/article/a618c45582c34de39dc0910aaa79ad47
Publikováno v:
Oncotarget
// Victor I. Seledtsov 1 and Galina V. Seledtsova 2 1 lmmanuel Kant Baltic Federal University, Kaliningrad, Russia 2 Institute for Fundamental and Clinical Immunology, Novosibirsk, Russia Correspondence to: Victor I. Seledtsov, email: seledtsov@rambl
Autor:
Galina V. Seledtsova, Ekaterina M. Morozova, Natalja D. Gazatova, Victor I. Seledtsov, M. E. Meniailo, V. V. Malashchenko
Publikováno v:
Hum Vaccin Immunother
Background: We studied direct effects of human granulocyte-macrophage colony stimulating factor (GM-CSF) on phenotypical characteristics and cytokine-production of non-activated and activated human monocytes/macrophages (Mc/Mphs) and T cells. Methods
Publikováno v:
Expert opinion on biological therapy. 21(3)
The immune system is able to exert both tumor-destructive and tumor-protective functions. Immunotherapeutic technologies aim to enhance immune-based anti-tumor activity and (or) weaken tumor-protective immunity.Cancer vaccination, antibody (Ab)-media
Autor:
Galina V. Seledtsova, Viacheslav Anatolievich Shmarov, V. V. Malashchenko, O. B. Melashchenko, Maxsim Evgenievich Meniailo, N. D. Gazatova, Victor I. Seledtsov, Andrei G. Goncharov
Publikováno v:
Cellular Immunology. 325:23-32
We investigated the direct effects of human granulocyte colony-stimulating factor (G-CSF) on functionality of human T-cell subsets. CD3+ T-lymphocytes were isolated from blood of healthy donors by positive magnetic separation. T cell activation with
Autor:
V. A. Shmarov, Galina V. Seledtsova, M. E. Meniailo, V. V. Malashchenko, Andrei G. Goncharov, O. B. Melashchenko, N. D. Gasatova, Victor I. Seledtsov
Publikováno v:
Medicinskaâ Immunologiâ, Vol 19, Iss 5, Pp 529-536 (2017)
CD3+T lymphocytes were isolated from normal donors by positive magnetic separation. Activation of the T cells with particles conjugated with antibodies to CD3, СD28 and СD2 molecules led to substantial increase in T cell production of interleukin-8
Publikováno v:
Expert review of clinical immunology. 15(7)
Introduction: Pathogenic memory CD4+ T cells are the mainspring of autoimmune and allergic disorders, suggesting that effective pathogenetic immunotherapy should be primarily directed onto their direct inactivation without affecting normal cells. Are
Autor:
M. E. Meniailo, V. A. Shmarov, Victor I. Seledtsov, N. M. Todosenko, O. B. Melashchenko, V. V. Malashchenko, N. D. Gazatova, Andrei G. Goncharov
Publikováno v:
European Cytokine Network. 27:102-107
СD3+ T lymphocytes were isolated by positive magnetic separation from the peripheral blood of healthy donors. In the absence of any additional activating stimuli, interleukin-7 (IL-7) was shown to augment the levels of T cells expressing CD25 activa
Autor:
Alexey A. Shishkov, Galina V. Seledtsova, Erika A. Kaschenko, Victor I. Seledtsov, N. D. Gazatova, A.G. Goncharov
Publikováno v:
European Journal of Dermatology. 26:138-143
New therapies for melanoma have yielded promising results, but their application is limited because of serious side-effects and only moderate impact on patient survival. Vaccine therapies may offer some hope by targeting tumor-specific responses, con
Autor:
Victor I. Seledtsov, M. E. Meniailo, Galina V. Seledtsova, Dmitriy N. Atochin, Igor A. Schepetkin, V. V. Malashchenko
Publikováno v:
European Journal of Pharmacology. 878:173116
c-Jun N-terminal kinase (JNK) is a critical mitogen activated protein kinase (MAPK) implicated in inflammatory processes, with IQ-1S (11H-indeno[1,2-b]quinoxalin-11-one oxime sodium salt) being a high-affinity JNK inhibitor with pronounced anti-infla