Výsledky vyhledávání - "Victor Hugo Sousa Gonçalves"

Akademický článek

SÍNTESE E AVALIAÇÃO DA ATIVIDADE CITOTÓXICA DE DERIVADOS DO EUGENOL CONTENDO NÚCLEOS 1,2,3-TRIAZÓLICOS

Autor: Poliana Aparecida Rodrigues Gazolla, Róbson Ricardo Teixeira, Adalberto Manoel da Silva, Boniek Gontijo Vaz, Géssica Adriana Vasconcelos, Raoni Pais Siqueira, Victor Hugo Sousa Gonçalves, Higor Sette Pereira, Gustavo Costa Bressan

Publikováno v: Química Nova, Vol 41, Iss 5, Pp 497-506

Eugenol is an aromatic compound found in several plant species. It presents important biological activities including cytotoxicity. In this paper, it is described the synthesis and the evaluation of the cytotoxic activity of eugenol derivatives beari

Externí odkaz: https://doaj.org/article/ad591672a69940a48f5a9755d850150b

Zobrazit plný text záznamu

Akademický článek

SÍNTESE E AVALIAÇÃO DAS ATIVIDADES FOTOPROTETORA, CITOTÓXICA E ANTIVIRAL CONTRA O ZIKA VÍRUS DE DERIVADOS TRIAZÓLICOS DA BENZOFENONA

Autor: Ângela M. A. Lima, Róbson R. Teixeira, Bianca F. da Silva, Raoni P. Siqueira, Ítalo E. P. da Silva, Edjon G. Santos, Maria Cecília Fernandes, Victor Hugo Sousa Gonçalves, Gustavo C. Bressan, Tiago Antonio de Oliveira Mendes, Sérgio O. de Paula, Adílson Vidal Costa, Marcelo H. dos Santos

Publikováno v: Química Nova, Vol 42, Iss 5, Pp 473-484

The benzophenones are synthetic and natural compounds presenting a variety of activities, including photoprotective, cytotoxic and antiviral. It is herein described the preparation of a series of twenty-seven benzophenone derivatives bearing 1,2,3-tr

Externí odkaz: https://doaj.org/article/735184dd2dec456cae1bb1fb470d2f13

Zobrazit plný text záznamu

Effect of the topical administration of N-(2-(4-bromophenylamino)-5-(trifluoromethyl)phenyl)nicotinamide compound in a murine subcutaneous melanoma model

Autor: Ana Paula Martins de Souza, Róbson Ricardo Teixeira, Juliana Alves do Vale, Graziela Domingues de Almeida Lima, Juliana Lopes Rangel Fietto, Gabriela Alves Moreira, Nara Clara Lazaroni E Merchid, Marcus Vinícius de Andrade Barros, Victor Hugo Sousa Gonçalves, Mariana Machado-Neves, Gustavo Costa Bressan, Wagner Luiz Pereira

Publikováno v: Anti-Cancer Drugs. 31:718-727

Conventional treatments for metastatic melanomas are still ineffective and generate numerous side effects, justifying the search for new therapies. The antimetastatic effect of the named N-(2-(4-bromophenylamino)-5-(trifluoromethyl)phenyl)nicotinamid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e44335053559b267a6185c440ae7a59
https://doi.org/10.1097/cad.0000000000000944

Zobrazit plný text záznamu

The SRPK inhibitor N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl) isonicotinamide (SRPIN340) increases the immune response against metastatic melanoma in mice

Autor: Gabriela Alves Moreira, Mônica Maria Magalhães Caetano, Juliana Alves do Vale, Janine Cerqueira de Paiva, Victor Hugo Sousa Gonçalves, Alisson Andrade Almeida, Lucas Viana Gomes Silva, Fernanda Rebellato Giordano Martim, Marcus Vinícius de Andrade Barros, Gabriela Rapozo Guimarães, Leandro de Oliveira Santos, Ana Paula Martins de Souza, Mariana Machado-Neves, Róbson Ricardo Teixeira, Abelardo Silva-Júnior, Juliana Lopes Rangel Fietto, Mariana Boroni, Leandro Licursi de Oliveira, Gustavo Costa Bressan

Publikováno v: Biochemical pharmacology. 203

Cancers have a strong relationship with immune cells in their microenvironment, which significantly influences tumor proliferation and progression. Thus, pharmacological strategies that stimulate the immune system to combat tumor cells are promising

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d690769fdcf8ef6a96ba3ef53b4934df
https://pubmed.ncbi.nlm.nih.gov/35787994

Zobrazit plný text záznamu

Synthesis of Nerol Derivatives Containing a 1,2,3-Triazole Moiety and Evaluation of Their Activities against Cancer Cell Lines

Autor: Róbson Ricardo Teixeira, H. S. Pereira, Victor Hugo Sousa Gonçalves, Adalberto Manoel da Silva, Gustavo Costa Bressan, Fávero Reisdorfer Paula, Eduardo Borges de Melo, Adilson Vidal Costa, Rafaela Salgado Ferreira, Raoni Pais Siqueira, Márcia M. C. Ferreira

Publikováno v: Journal of the Brazilian Chemical Society, Volume: 30, Issue: 3, Pages: 541-561, Published: MAR 2019
Journal of the Brazilian Chemical Society v.30 n.3 2019
Journal of the Brazilian Chemical Society
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

In the present investigation, a collection of twenty two nerol derivatives, containing 1,2,3-triazolic appendages, was synthesized and screened in vitro for their cytotoxic activity against HL60, Nalm6, and Jurkat human leukemia cells as well as agai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26610fa74b272acb2fceccce70bc4bc9
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532019000300541&lng=en&tlng=en

Zobrazit plný text záznamu

Synthesis and evaluation of the photoprotective, cytotoxic and antiviral activity of benzophenone derivatives containing 1,2,3-triazolic portions

Autor: Bianca F. da Silva, Ítalo E. P. da Silva, Adilson Vidal Costa, Sérgio Oliveira de Paula, Ângela M. A. Lima, Maria Cecília Fernandes, Edjon G. Santos, Raoni Pais Siqueira, Marcelo Henrique dos Santos, Victor Hugo Sousa Gonçalves, Tiago Antônio de Oliveira Mendes, Róbson Ricardo Teixeira, Gustavo Costa Bressan

Publikováno v: Repositório Institucional da UFMG
Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
Química Nova, Vol 42, Iss 5, Pp 473-484
Química Nova v.42 n.5 2019
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bfabeeaa0f765668572bd3ac345305

Zobrazit plný text záznamu

Trifluoromethyl arylamides with antileukemia effect and intracellular inhibitory activity over serine/arginine-rich protein kinases (SRPKs)

Autor: H. S. Pereira, Gustavo Costa Bressan, Abelardo Silva Júnior, Márcia Rogéria de Almeida, Victor Hugo Sousa Gonçalves, Leandro Licursi de Oliveira, Róbson Ricardo Teixeira, Raoni Pais Siqueira, Éverton de Almeida Alves Barbosa, Juliana Lopes Rangel Fietto, Thiago Souza Onofre, Marcus Vinícius de Andrade Barros

Publikováno v: LOCUS Repositório Institucional da UFV
Universidade Federal de Viçosa (UFV)
instacron:UFV

The serine/arginine-rich protein kinases (SRPKs) have frequently been found with altered activity in a number of cancers, suggesting they could serve as potential therapeutic targets in oncology. Here we describe the synthesis of a series of twenty-t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2173192f3f8ad42eb17e5aa545bd5f9
https://pubmed.ncbi.nlm.nih.gov/28407594

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání