Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Victor H.F. Lee"'
Autor:
Alan W.L. Mui, Anne W.M. Lee, W.T. Ng, Victor H.F. Lee, Varut Vardhanabhuti, Shei S.Y. Man, Daniel T.T. Chua, X.Y. Guan
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 24, Iss , Pp 30-35 (2022)
Background and Purpose: Functional imaging has an established role in therapeutic monitoring of cancer treatments. This study evaluated the correlations of tumour permeability parameters derived from dynamic contrast-enhanced magnetic resonance imagi
Externí odkaz:
https://doaj.org/article/3de0cab5aa52432685b3ea46cbb68b56
Autor:
Alan W.L. Mui, Anne W.M. Lee, Wai-Tong Ng, Victor H.F. Lee, Varut Vardhanabhuti, Shei-Yee Man, Daniel T.T. Chua, Xin-Yuan Guan
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 27, Iss , Pp 100458- (2023)
Background and Purpose: Physiological changes in tumour occur much earlier than morphological changes. They can potentially be used as biomarkers for therapeutic response prediction. This study aimed to investigate the optimal time for early therapeu
Externí odkaz:
https://doaj.org/article/bc5121b6d16341899aac04a28174b95a
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Table S7. Primary PK parameters for spartalizumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4654f298b3b5b95f2d1fe549d47835ec
https://doi.org/10.1158/1078-0432.22484064
https://doi.org/10.1158/1078-0432.22484064
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Figure S2. Adverse events in crossover group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28793f51c06cf4dd88863fe91eeb4c0b
https://doi.org/10.1158/1078-0432.22484097.v1
https://doi.org/10.1158/1078-0432.22484097.v1
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Table S2. Chemotherapy regimens given to patients in the chemotherapy arm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e697e4b2a33e6eb31107d28fe03682
https://doi.org/10.1158/1078-0432.22484082.v1
https://doi.org/10.1158/1078-0432.22484082.v1
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Table S5. Adverse events ({greater than or equal to} 15% incidence of all grades events in any of the patient treatment arms)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db369c8bd894b191faa792dd64a2b3a
https://doi.org/10.1158/1078-0432.22484070.v1
https://doi.org/10.1158/1078-0432.22484070.v1
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Table S6. Adverse events of special interest (patients treated with spartalizumab)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f0d6f1f0449b030b61c2ad5339b24d
https://doi.org/10.1158/1078-0432.22484067
https://doi.org/10.1158/1078-0432.22484067
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Purpose:No standard treatment exists for platinum-refractory, recurrent/metastatic nasopharyngeal cancer (NPC). This phase II study (NCT02605967) evaluated progression-free survival (PFS) of spartalizumab, an antiprogrammed cell death protein-1 (PD-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16654b198e7fddf4a1e74eebe9adc8c2
https://doi.org/10.1158/1078-0432.c.6531318
https://doi.org/10.1158/1078-0432.c.6531318
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Figure S3. Best percentage change from baseline in sum of diameters of target lesions for patients treated with spartalizumab (A) and chemotherapy (B)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e129ac1ba81c71214802a67ed0d560d
https://doi.org/10.1158/1078-0432.22484088
https://doi.org/10.1158/1078-0432.22484088
Autor:
Darren W-T. Lim, Luigi Manenti, Romain Séchaud, Jennifer Mataraza, Hongzi Liang, Yao Yao, Sebastian Szpakowski, Juan Gonzalez-Maffe, Steven McCune, Joël Guigay, Ammar Sukari, Alexander I. Spira, Zujun Li, Pei-Jen Lou, Victor H.F. Lee, Suebpong Tanasanvimon, Brigette B.Y. Ma, Somvilai Chakrabandhu, Po Chung Chan, Chia-Jui Yen, Li Zhang, Arunee Dechaphunkul, Roger K-C Ngan, Shau-Hsuan Li, Hung-Ming Wang, Caroline Even
Supplemental Table S1. Patient disposition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d05607a694aad5f719edf7b9f542a4b
https://doi.org/10.1158/1078-0432.22484085.v1
https://doi.org/10.1158/1078-0432.22484085.v1