Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Victor H Leyva-Grado"'
Autor:
Mila Brum Ortigoza, Oliver Dibben, Jad Maamary, Luis Martinez-Gil, Victor H Leyva-Grado, Pablo Abreu, Juan Ayllon, Peter Palese, Megan L Shaw
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002668 (2012)
Influenza viruses continue to pose a major public health threat worldwide and options for antiviral therapy are limited by the emergence of drug-resistant virus strains. The antiviral cytokine, interferon (IFN) is an essential mediator of the innate
Externí odkaz:
https://doaj.org/article/2658e6b4c2e042d0aa9be6c8b270cfdb
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Emergence and re-emergence of respiratory virus infections represent a significant threat to global public health, as they occur seasonally and less frequently (such as in the case of influenza virus) as pandemic infections. Some of these viruses hav
Externí odkaz:
https://doaj.org/article/36fd3bc53e9d47179bd0f9f51843d017
Autor:
Carly M. Bliss, Alec W. Freyn, Tom G. Caniels, Victor H. Leyva-Grado, Raffael Nachbagauer, Weina Sun, Gene S. Tan, Virginia L. Gillespie, Meagan McMahon, Florian Krammer, Adrian V.S. Hill, Peter Palese, Lynda Coughlan
Publikováno v:
Molecular therapy, 30(5), 2024-2047. Nature Publishing Group
Conventional influenza vaccines fail to confer broad protection against diverse influenza A viruses with pandemic potential. Efforts to develop a universal influenza virus vaccine include refocusing immunity towards the highly conserved stalk domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ae760cfa9ec74e4507ccc9391dd171
https://orca.cardiff.ac.uk/id/eprint/146715/3/1-s2.0-S1525001622000119-main.pdf
https://orca.cardiff.ac.uk/id/eprint/146715/3/1-s2.0-S1525001622000119-main.pdf
Autor:
Mohammad Amin Behzadi, Mandana Namayandeh, Victor H. Leyva-Grado, Mazyar Ziyaeyan, Atoosa Ziyaeyan, Hedayat Dorzaban, Roya Feyznezhad, Marzieh Jamalidoust
Publikováno v:
BMC Infectious Diseases
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-12 (2019)
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-12 (2019)
Background Viral hepatitis is a global public health problem affecting millions of people worldwide, causing thousands of deaths due to acute and persistent infection, cirrhosis, and liver cancer. Providing updated serologic data can improve both sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8e537a555110a2fa4ccb1dd291e689
http://europepmc.org/articles/PMC6889522
http://europepmc.org/articles/PMC6889522
Autor:
Peter Palese, Victor H. Leyva-Grado
Publikováno v:
Antiviral Research. 142:12-15
Oseltamivir is an influenza neuraminidase inhibitor that along with supportive therapy has shown to help critically ill patients infected with H7N9 and H1N1pdm influenza virus strains to recover from disease. The standard of care recommends the admin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90efa081d36e794e4061f3de52c1c879
https://doi.org/10.1016/j.antiviral.2017.03.002
https://doi.org/10.1016/j.antiviral.2017.03.002
Publikováno v:
ACS infectious diseases. 5(10)
Two classes of antivirals targeting the viral neuraminidase (NA) and endonuclease are currently the only clinically useful drugs for the treatment of influenza. However, resistance to both antivirals has been observed in clinical isolates, and there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389e72b9fa4c2dcffafc88510fbf4bee
https://pubmed.ncbi.nlm.nih.gov/31448902
https://pubmed.ncbi.nlm.nih.gov/31448902
Autor:
Julia A. Brown, Maria C. Bermúdez González, Fortuna Arumemi, Jean K. Lim, James Duehr, Peter Palese, Matthew J. Evans, Harrison Dulin, Felix Broecker, Mark J. Bailey, Gene S. Tan, Viviana Simon, Rong Hai, Florian Krammer, Victor H. Leyva-Grado
Publikováno v:
Nature Communications
Nature communications, vol 9, iss 1
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature communications, vol 9, iss 1
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Zika virus is a mosquito-borne flavivirus closely related to dengue virus that can cause severe disease in humans, including microcephaly in newborns and Guillain-Barré syndrome in adults. Specific treatments and vaccines for Zika virus are not curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647367d1b43e6084bed93e146c0eab9f
https://doi.org/10.1038/s41467-018-07008-0
https://doi.org/10.1038/s41467-018-07008-0
Autor:
Victor H. Leyva-Grado, Megan E. Ermler, Michael Schotsaert, Ma G. Gonzalez, Virginia Gillespie, Jean K. Lim, Adolfo García-Sastre, Christine A. Biron
Publikováno v:
mBio
mBio, Vol 8, Iss 2 (2017)
mBio, Vol 8, Iss 2, p e00229-17 (2017)
mBio, Vol 8, Iss 2 (2017)
mBio, Vol 8, Iss 2, p e00229-17 (2017)
An exacerbated immune response is one of the main causes of influenza-induced lung damage during infection. The molecular mechanisms regulating the fate of the initial immune response to infection, either as a protective response or as detrimental im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460a49c0d6dc90ca0d4fd121cec99264
http://europepmc.org/articles/PMC5371412
http://europepmc.org/articles/PMC5371412
Autor:
Atoosa Ziyaeyan, Gholamreza Pouladfar, Mohammad Amin Behzadi, Victor H. Leyva-Grado, Kourosh Azizi, Sanaz Salek, Aghyl Jaber Hashemi, Mazyar Ziyaeyan, Marzieh Jamalidoust, Hedayat Dorzaban
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0007022 (2018)
PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0007022 (2018)
West Nile virus (WNV) and Zika virus (ZIKV) are mosquito-borne viral infections. Over the past few decades, WNV has been associated with several outbreaks involving high numbers of neuroinvasive diseases among humans. The recent re-emergence of ZIKV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248e875e3172523bdb3ba82c5a394488
https://doi.org/10.1371/journal.pntd.0007022
https://doi.org/10.1371/journal.pntd.0007022
Publikováno v:
Journal of Virology. 87:8272-8281
Influenza A virus is a major human pathogen responsible for seasonal epidemics as well as pandemic outbreaks. Due to the continuing burden on human health, the need for new tools to study influenza virus pathogenesis as well as to evaluate new therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3433d90d64b867bfddb1cbbb5684573
https://doi.org/10.1128/jvi.00969-13
https://doi.org/10.1128/jvi.00969-13