Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Victor H Engelhard"'
Autor:
Nicole L. Edmonds, Sarah E Gradecki, Priya Katyal, Kevin T Lynch, Anne M Stowman, Alejandro A Gru, Victor H Engelhard, Craig L Slingluff, Ileana S. Mauldin
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTTertiary lymphoid structures (TLS) are ectopic lymphoid structures that can arise in human cancers and are associated with improved overall survival (OS) and response to immune checkpoint blockade (ICB) in several cancers, including non-desmo
Externí odkaz:
https://doaj.org/article/76a7c46882b34e41922abb9223121455
Autor:
Robin S. Lindsay, Marit M. Melssen, Katarzyna Stasiak, Jessica L. Annis, Amber N. Woods, Anthony B. Rodriguez, Michael G. Brown, Victor H. Engelhard
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionStudies of NK cells in tumors have primarily focused on their direct actions towards tumor cells. We evaluated the impact of NK cells on expression of homing receptor ligands on tumor vasculature, intratumoral T cell number and function,
Externí odkaz:
https://doaj.org/article/1e671be8b5924d3186d6f50f6bb3543b
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tumor-associated tertiary lymphoid structures are ectopic lymphoid aggregates that have considerable morphological, cellular, and molecular similarity to secondary lymphoid organs, particularly lymph nodes. Tumor vessels expressing peripheral node ad
Externí odkaz:
https://doaj.org/article/6a65bdb4b3ab446ca08a33a0ce67ef8b
Autor:
Minyoung Kwak, Gulsun Erdag, Katie M. Leick, Stefan Bekiranov, Victor H. Engelhard, Craig L. Slingluff
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Immune cells in the tumor microenvironment have prognostic value. In preclinical models, recruitment and infiltration of these cells depends on immune cell homing (ICH) genes such as chemokines, cell adhesion molecules, and integr
Externí odkaz:
https://doaj.org/article/c15cf06be1c44250be629a5c814fea4a
Autor:
Ileana S Mauldin, Nolan A Wages, Max O Meneveau, Kevin T Lynch, Samuel J Young, Craig L Slingluff Jr, Victor H Engelhard
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Tertiary lymphoid structures (TLSs) are immune aggregates in peripheral tissues that may support adaptive immune responses. Their presence has been associated with clinical response to checkpoint blockade therapy (CBT), but it is unknown w
Externí odkaz:
https://doaj.org/article/bc704d967f104405830c38beb6d775f1
Autor:
Mark E Smolkin, Gina R Petroni, Kimberly A Chianese-bullock, Kelly T Smith, Geoffrey Weiss, Nico Buettner, Mark Cobbold, Jeffrey Shabanowitz, Nikole Varhegyi, Elizabeth Gaughan, Victor H Engelhard, Rebecca C Obeng, Kara L Cummings, Angela L Ambakhutwala, Amanda Lulu, Paisley Myers, Keira E Mahoney, Emily H Hall, Kathleen Haden, Donald F Hunt, Craig L Slingluff, Jr
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Phosphorylated peptides presented by MHC molecules represent a new class of neoantigens expressed on cancer cells and recognized by CD8 T-cells. These peptides are promising targets for cancer immunotherapy. Previous work identified an HLA
Externí odkaz:
https://doaj.org/article/2f1ba13970c949eeb55d8d1382a456e4
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Until a few years ago, lymphatic vessels and lymphatic endothelial cells (LEC) were viewed as part of a passive conduit for lymph and immune cells to reach lymph nodes (LN). However, recent work has shown that LEC are active immunological players who
Externí odkaz:
https://doaj.org/article/ebb7e4f41efb400bbbc3287fc17eccd4
Autor:
Stella J. Berendam, Alexander F. Koeppel, Nicole R. Godfrey, Sherin J. Rouhani, Amber N. Woods, Anthony B. Rodriguez, J. David Peske, Kara L. Cummings, Stephen D. Turner, Victor H. Engelhard
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Lymphatic and blood vessels are formed by specialized lymphatic endothelial cells (LEC) and blood endothelial cells (BEC), respectively. These endothelial populations not only form peripheral tissue vessels, but also critical supporting structures in
Externí odkaz:
https://doaj.org/article/db1eca5d9c874b308d3564b91c460711
Autor:
Victor H. Engelhard, Susan C. Modesitt, Craig L. Slingluff, Kimberly A. Chianese-Bullock, Rachel M. Lacy, Dennis Underwood, Paisley T. Myers, Erin D. Jeffery, Kara L. Cummings, Amanda M. Lulu
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c83d943b3bb9a7554758c8a99b417e8
https://doi.org/10.1158/2326-6066.22544321
https://doi.org/10.1158/2326-6066.22544321
Autor:
Victor H. Engelhard, Craig L. Slingluff, Ukpong Eyo, Sjoerd H. van der Burg, Cornelis J.M. Melief, Mark R. Conaway, Melanie R. Rutkowski, Salwador Cyranowski, Amanda M. Briegel, Anthony B. Rodriguez, Katarzyna Stasiak, Robin S. Lindsay, Marit M. Melssen
Movement of cells in anti-CD49b treated tumor slices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4478c19fb6091a6a24c671662898eeb3
https://doi.org/10.1158/2326-6066.22543948
https://doi.org/10.1158/2326-6066.22543948