Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Victor Gourain"'
Autor:
Séverine Ménoret, Laurent Tesson, Séverine Remy, Victor Gourain, Céline Sérazin, Claire Usal, Aude Guiffes, Vanessa Chenouard, Laure-Hélène Ouisse, Malika Gantier, Jean-Marie Heslan, Cynthia Fourgeux, Jeremie Poschmann, Carole Guillonneau, Ignacio Anegon
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Regulatory T cells (Treg) in diverse species include CD4+ and CD8+ T cells. In all species, CD8+ Treg have been only partially characterized and there is no rat model in which CD4+ and CD8+ FOXP3+ Treg are genetically tagged. Resu
Externí odkaz:
https://doaj.org/article/a5f7fd4d1ec14f8a9408162e7c0a4594
Autor:
Ava Galland, Victor Gourain, Karima Habbas, Yonca Güler, Elisabeth Martin, Claudine Ebel, Manuela Tavian, Laurent Vallat, Marie‐Pierre Chenard, Laurent Mauvieux, Jean‐Noël Freund, Isabelle Duluc, Claire Domon‐Dell
Publikováno v:
Molecular Oncology, Vol 15, Iss 9, Pp 2318-2329 (2021)
The intestine‐specific caudal‐related homeobox gene‐2 (CDX2) homeobox gene, while being a tumor suppressor in the gut, is ectopically expressed in a large proportion of acute leukemia and is associated with poor prognosis. Here, we report that
Externí odkaz:
https://doaj.org/article/897ff20dc4204936a7914f96da43039a
Autor:
Nane C. Kuznik, Valeria Solozobova, Irene I. Lee, Nicole Jung, Linxiao Yang, Karin Nienhaus, Emmanuel A. Ntim, Jaice T. Rottenberg, Claudia Muhle-Goll, Amrish Rajendra Kumar, Ravindra Peravali, Simone Gräßle, Victor Gourain, Célia Deville, Laura Cato, Antje Neeb, Marco Dilger, Christina A. Cramer von Clausbruch, Carsten Weiss, Bruno Kieffer, G. Ulrich Nienhaus, Myles Brown, Stefan Bräse, Andrew C.B. Cato
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104175- (2022)
Summary: BAG1 is a family of polypeptides with a conserved C-terminal BAG domain that functions as a nucleotide exchange factor for the molecular chaperone HSP70. BAG1 proteins also control several signaling processes including proteostasis, apoptosi
Externí odkaz:
https://doaj.org/article/ef7d174a265a47ad8c77177cd0835a85
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Whether a gene involved in distinct tissue or cell functions exerts a core of common molecular activities is a relevant topic in evolutionary, developmental, and pathological perspectives. Here, we addressed this question by focusing on the transcrip
Externí odkaz:
https://doaj.org/article/34a95261e9014448a96b5fa2c00eadc6
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Zebrafish is an attractive model to investigate regeneration of the nervous system. Despite major progress in our understanding of the underlying processes, the transcriptomic changes are largely unknown. We carried out a computational analysis of th
Externí odkaz:
https://doaj.org/article/b5d879c9ec944d069be328ddf913761b
Autor:
Masanari Takamiya, Johannes Stegmaier, Andrei Yu Kobitski, Benjamin Schott, Benjamin D Weger, Dimitra Margariti, Angel R Cereceda Delgado, Victor Gourain, Tim Scherr, Lixin Yang, Sebastian Sorge, Jens C Otte, Volker Hartmann, Jos van Wezel, Rainer Stotzka, Thomas Reinhard, Günther Schlunck, Thomas Dickmeis, Sepand Rastegar, Ralf Mikut, Gerd Ulrich Nienhaus, Uwe Strähle
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008774 (2020)
Cranial neural crest (NC) contributes to the developing vertebrate eye. By multidimensional, quantitative imaging, we traced the origin of the ocular NC cells to two distinct NC populations that differ in the maintenance of sox10 expression, Wnt sign
Externí odkaz:
https://doaj.org/article/8e4da45e746442678c656ac1c39e9a74
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 1177-1183 (2018)
Protein tyrosine phosphatases and glucocorticoids are known to regulate allergic and antiallergic action in activated mast cells. Here we provide RNA sequencing and quantitative real-time PCR data from bone marrow derived mast cells, for wild-type an
Externí odkaz:
https://doaj.org/article/70e775270d7242cb9728fbc5a783e825
Autor:
Marie Mayrhofer, Victor Gourain, Markus Reischl, Pierre Affaticati, Arnim Jenett, Jean-Stephane Joly, Matteo Benelli, Francesca Demichelis, Pietro Luigi Poliani, Dirk Sieger, Marina Mione
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 1, Pp 15-28 (2017)
Somatic mutations activating MAPK and PI3K signalling play a pivotal role in both tumours and brain developmental disorders. We developed a zebrafish model of brain tumours based on somatic expression of oncogenes that activate MAPK and PI3K signalli
Externí odkaz:
https://doaj.org/article/6ea228aad95c4f3bb6d9f799cee87c3c
Autor:
Viviana Anelli, Anita Ordas, Susanne Kneitz, Leonel Munoz Sagredo, Victor Gourain, Manfred Schartl, Annemarie H. Meijer, Marina Mione
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Ras genes are among the most commonly mutated genes in human cancer; yet our understanding of their oncogenic activity at the molecular mechanistic level is incomplete. To identify downstream events that mediate ras-induced cellular transformation in
Externí odkaz:
https://doaj.org/article/b2454468f17d4d9babc9791b2eb3b4d5
Publikováno v:
Data in Brief, Vol 8, Iss , Pp 61-68 (2016)
Formation of the contractile myofibril of the skeletal muscle is a complex process which when perturbed leads to muscular dystrophy. Herein, we provide a mRNAseq dataset on three different zebrafish mutants affecting muscle organization during embryo
Externí odkaz:
https://doaj.org/article/be63221c574042b59939d6660fff6c9e