Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Victor García-González"'
Autor:
Angel Pulido-Capiz, Brenda Chimal-Vega, Luis Pablo Avila-Barrientos, Alondra Campos-Valenzuela, Raúl Díaz-Molina, Raquel Muñiz-Salazar, Octavio Galindo-Hernández, Victor García-González
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1179 (2024)
Approximately 80% of breast cancer (BC) cases are estrogen receptor positive (ER+) and sensitive to hormone treatment; Tamoxifen is a prodrug, and its main plasmatic active metabolites are 4-hydroxytamoxifen (4-OH Tam) and endoxifen. Despite the effe
Externí odkaz:
https://doaj.org/article/829b538cb52249cb967885c83550311a
Autor:
César Y. Castañeda-Sánchez, Brenda Chimal-Vega, Roberto León-Gutiérrez, Adrián Ernesto Araiza-Robles, Nicolás Serafín-Higuera, Angel Pulido-Capiz, Ignacio A. Rivero, Raúl Díaz-Molina, Manuel Alatorre-Meda, Eustolia Rodríguez-Velázquez, Victor García-González
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 742 (2024)
Dyslipidemias involving high concentrations of low-density lipoproteins (LDLs) increase the risk of developing triple-negative breast cancer (TNBC), wherein cholesterol metabolism and protein translation initiation mechanisms have been linked with ch
Externí odkaz:
https://doaj.org/article/339bd36f55b1418589cf08d24c619325
Resistin Induces Migration and Invasion in PC3 Prostate Cancer Cells: Role of Extracellular Vesicles
Autor:
Mario Israel Oregel-Cortez, Héctor Frayde-Gómez, Georgina Quintana-González, Victor García-González, Jose Gustavo Vazquez-Jimenez, Octavio Galindo-Hernández
Publikováno v:
Life, Vol 13, Iss 12, p 2321 (2023)
Resistin is an adipokine with metabolic and inflammatory functions. Epidemiological and translational studies report that an increase in plasma levels and tissue expression of resistin increases the aggressiveness of prostate tumor cells. Extracellul
Externí odkaz:
https://doaj.org/article/359340c68f73404a9c874d339037ffd4
Autor:
Javier de Jesús Vasconcelos-Ulloa, Victor García-González, Benjamín Valdez-Salas, José Gustavo Vázquez-Jiménez, Ignacio Rivero-Espejel, Raúl Díaz-Molina, Octavio Galindo-Hernández
Publikováno v:
Molecules, Vol 28, Iss 11, p 4524 (2023)
Cancer is a serious health problem due to the complexity of establishing an effective treatment. The purpose of this work was to evaluate the activity of a triazaspirane as a migration and invasion inhibitor in PC3 prostatic tumor cells through a pos
Externí odkaz:
https://doaj.org/article/1951da6cd23e4dda9c79680f1d54c3dd
Autor:
Martha E. Ávila-Cossío, Ignacio A. Rivero, Victor García-González, Manuel Alatorre-Meda, Eustolia Rodríguez-Velázquez, Julio C. Calva-Yáñez, Karla A. Espinoza, Ángel Pulido-Capiz
Publikováno v:
ACS Omega, Vol 5, Iss 10, Pp 5249-5257 (2020)
Externí odkaz:
https://doaj.org/article/422b3ff7cf2c4b99bbc7bd1a06ba01ec
Autor:
Alina González-Ortiz, Angel Pulido-Capiz, César Y. Castañeda-Sánchez, Esmeralda Ibarra-López, Octavio Galindo-Hernández, Maritza Anahí Calderón-Fernández, Leslie Y. López-Cossio, Raul Díaz-Molina, Brenda Chimal-Vega, Nicolás Serafín-Higuera, Iván Córdova-Guerrero, Victor García-González
Publikováno v:
Cells, Vol 11, Iss 24, p 4069 (2022)
Cells employ several adaptive mechanisms under conditions of accelerated cell division, such as the unfolded protein response (UPR). The UPR is composed of a tripartite signaling system that involves ATF6, PERK, and IRE1, which maintain protein homeo
Externí odkaz:
https://doaj.org/article/9b69f4f5558b4ac796f47464c0a6c427
Autor:
Lizbeth Guevara-Olaya, Brenda Chimal-Vega, César Yahel Castañeda-Sánchez, Leslie Y. López-Cossio, Angel Pulido-Capiz, Octavio Galindo-Hernández, Raúl Díaz-Molina, Josefina Ruiz Esparza-Cisneros, Victor García-González
Publikováno v:
Metabolites, Vol 12, Iss 8, p 754 (2022)
Dyslipidemia is described as a hallmark of metabolic syndrome, promoting a stage of metabolic inflammation (metainflammation) that could lead to misbalances in energetic metabolism, contributing to insulin resistance, and modifying intracellular chol
Externí odkaz:
https://doaj.org/article/e7b5b92993554e5886c294520a81f91d
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Our study tested the proposal that c-Myc activation in macrophages is differentially carried out dependent on the intracellular oxidative state of cells and potentially associated to the process of atherogenesis. Under our experimental condi
Externí odkaz:
https://doaj.org/article/7f1fe1f65f264017bc744ab675a95fa7
Autor:
Israel Martínez-Navarro, Raúl Díaz-Molina, Angel Pulido-Capiz, Jaime Mas-Oliva, Ismael Luna-Reyes, Eustolia Rodríguez-Velázquez, Ignacio A. Rivero, Marco A. Ramos-Ibarra, Manuel Alatorre-Meda, Victor García-González
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1201 (2020)
Human islet amyloid polypeptide (hIAPP) corresponds to a 37-residue hormone present in insulin granules that maintains a high propensity to form β-sheet structures during co-secretion with insulin. Previously, employing a biomimetic approach, we pro
Externí odkaz:
https://doaj.org/article/f6da3b0dc9f44000a11a7970e2217e9c
Autor:
Eduardo Noriega-Iribe, Laura Díaz-Rubio, Arturo Estolano-Cobián, Victor Wagner Barajas-Carrillo, José M. Padrón, Ricardo Salazar-Aranda, Raúl Díaz-Molina, Victor García-González, Rocio Alejandra Chávez-Santoscoy, Daniel Chávez, Iván Córdova-Guerrero
Publikováno v:
Applied Sciences, Vol 10, Iss 8, p 2889 (2020)
The employment of privileged scaffolds in medicinal chemistry supplies scientists with a solid start in the search for new and improved therapeutic molecules. One of these scaffolds is the imidazole ring, from which several derivatives have shown a w
Externí odkaz:
https://doaj.org/article/985b58094787436dae66079de8e9b99c