Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Victor G. Sharov"'
Autor:
Monika Duda, Agnes M. Azimzadeh, Wenhong Xu, Karen M. O'Shea, Brian R. Barrows, Victor G. Sharov, William S. Harris, William C. Stanley, Anselm Tintinu, Hani N. Sabbah, David J. Chess, Ramzi J. Khairallah
Publikováno v:
Cardiovascular Research. 81:319-327
Aims Clinical studies suggest that intake of ω-3 polyunsaturated fatty acids (ω-3 PUFA) may lower the incidence of heart failure. Dietary supplementation with ω-3 PUFA exerts metabolic and anti-inflammatory effects that could prevent left ventricl
Autor:
Sidney Goldstein, Victor G. Sharov, Sudhish Mishra, Ramesh C. Gupta, Valerio Zacà, Sharad Rastogi, Mengjun Wang, Hani N. Sabbah
Publikováno v:
Cardiology. 112:294-302
Objectives: β-Blockers are standard therapy for patients with heart failure (HF). This study compared the effects of chronic monotherapy with 2 different β1-selective adrenoceptor blockers, namely atenolol and metoprolol succinate, on left ventricu
Autor:
Alice Jiang, Sharad Rastogi, Sidney Goldstein, Mengjun Wang, Victor G. Sharov, Makoto Imai, Valerio Zacà, Hani N. Sabbah
Publikováno v:
Journal of the American College of Cardiology. 50:551-557
Objectives This study examined the effects of long-term monotherapy with rosuvastatin (RSV) on the progression of left ventricular (LV) dysfunction and remodeling in dogs with heart failure (HF). Background 3-hydroxy-3-methylglutaryl coenzyme A reduc
Publikováno v:
Journal of Molecular and Cellular Cardiology. 42:150-158
We used isolated cardiomyocytes to investigate a possible role of mitochondrial permeability transition pore in mitochondrial abnormalities associated with heart failure. Cardiomyocytes were isolated from LV myocardium of normal control dogs and dogs
Autor:
Martin E. Young, Julie H. Rennison, Hani N. Sabbah, William C. Stanley, Kou Yi Tserng, Tracy A. McElfresh, Isidore C. Okere, Brian D. Hoit, Paul Ernsberger, Margaret P. Chandler, Victor G. Sharov
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 291:H38-H44
Fatty acids are the primary fuel for the heart and are ligands for peroxisome proliferator-activated receptors (PPARs), which regulate the expression of genes encoding proteins involved in fatty acid metabolism. Saturated fatty acids, particularly pa
Publikováno v:
Heart Failure Reviews. 10:297-303
In the setting of chronic heart failure (HF), progressive left ventricular (LV) dysfunction and chamber remodeling may be due, in part, to altered expression and disorganization of cytoskeletal, linkage and extracellular proteins. This brief review d
Autor:
Pervaiz A. Chaudhry, Sharad Rastogi, Anastassia Todor, Takayuki Mishima, Hani N. Sabbah, Sudhish Mishra, Albertas I. Undrovinas, Elaine J. Tanhehco, George Suzuki, Victor G. Sharov, Ramesh C Gupta
Publikováno v:
Circulation Research. 93:1095-1101
Passive mechanical containment of failing left ventricle (LV) with the Acorn Cardiac Support Device (CSD) was shown to prevent progressive LV dilation in dogs with heart failure (HF) and increase ejection fraction. To examine possible mechanisms for
Autor:
Anastasia Todor, Victor G. Sharov, Alexander D. Shepard, Iraklis I. Pipinos, Petros V. Anagnostopoulos, Konstantinos Filis, Hani N. Sabbah, Asterios N. Katsamouris
Publikováno v:
Journal of Vascular Surgery. 38(4):827-832
ObjectiveDiscrete morphologic, enzymatic and functional changes in skeletal muscle mitochondria have been demonstrated in patients with peripheral arterial disease (PAD). We examined mitochondrial respiration in the gastrocnemius muscle of nine patie
Autor:
Victor G. Sharov, Hideaki Morita, Elaine J. Tanhehco, Anastassia Todor, Hani N. Sabbah, George Suzuki
Publikováno v:
European Journal of Heart Failure. 5:121-129
Background: Apoptosis may contribute to the myocardial dysfunction associated with heart failure (HF). Activation of the p38 MAPK cascade can induce apoptosis in non-cardiac cells through increased expression of Fas-L, or through decreased expression
Autor:
Victor G. Sharov, Sidney Goldstein, Pervaiz A. Chaudhry, Elaine J. Tanhehco, Anastassia Todor, Hani N. Sabbah, Takayuki Mishima, George Suzuki, Sharad Rostogi, Omar Nass, Petros V. Anagnostopoulos, Ramesh C Gupta
Publikováno v:
British Journal of Pharmacology. 138:301-309
1. We examined the effects of eprosartan, an AT(1) receptor antagonist, on the progression of left ventricular (LV) dysfunction and remodelling in dogs with heart failure (HF) produced by intracoronary microembolizations (LV ejection fraction, EF 30