Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Victor Fedorenko"'
Publikováno v:
Antibiotics, Vol 13, Iss 2, p 115 (2024)
StrR-like pathway-specific transcriptional regulators (PSRs) function as activators in the biosynthesis of various antibiotics, including glycopeptides (GPAs), aminoglycosides, aminocoumarins, and ramoplanin-like lipodepsipeptides (LDPs). In particul
Externí odkaz:
https://doaj.org/article/2f983cbcc0e647bebb25020bfc2da898
Autor:
Borys Dolya, Olena Hryhorieva, Khrystyna Sorochynska, Maria Lopatniuk, Iryna Ostash, Vasylyna-Marta Tseduliak, Eva Baggesgaard Sterndorff, Tue Sparholt Jørgensen, Tetiana Gren, Yuriy Dacyuk, Tilmann Weber, Andriy Luzhetskyy, Victor Fedorenko, Bohdan Ostash
Publikováno v:
Microorganisms, Vol 11, Iss 5, p 1176 (2023)
Streptomyces albidoflavus J1074 is a popular platform to discover novel natural products via the expression of heterologous biosynthetic gene clusters (BGCs). There is keen interest in improving the ability of this platform to overexpress BGCs and, c
Externí odkaz:
https://doaj.org/article/074ec5aa5e7f49d4be3db5ee7c5b30f6
Autor:
Oleksandr Yushchuk, Iryna Ostash, Eva Mösker, Iryna Vlasiuk, Maksym Deneka, Christian Rückert, Tobias Busche, Victor Fedorenko, Jörn Kalinowski, Roderich D. Süssmuth, Bohdan Ostash
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Actinobacteria are among the most prolific sources of medically and agriculturally important compounds, derived from their biosynthetic gene clusters (BGCs) for specialized (secondary) pathways of metabolism. Genomics witnesses that the majo
Externí odkaz:
https://doaj.org/article/057a7057442146c8ad1690394f59b75a
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Glycopeptide antibiotics are valuable natural metabolites endowed with different pharmacological properties, among them are dalbaheptides used to treat different infections caused by multidrug-resistant Gram-positive pathogens. Dalbaheptides are prod
Externí odkaz:
https://doaj.org/article/d7d8008f615d4a4e80deeb9d1b4fcf9d
Publikováno v:
BBA Advances, Vol 2, Iss , Pp 100065- (2022)
Moenomycins, such as moenomycin A, are phosphoglycolipid specialized metabolites produced by a number of actinobacterial species. They are among the most potent antibacterial compounds known to date, which drew numerous studies directed at various as
Externí odkaz:
https://doaj.org/article/47bb1abd8c2144fd8509e6d84253fab7
Publikováno v:
Antibiotics, Vol 10, Iss 12, p 1533 (2021)
The spread of antimicrobial resistance (AMR) creates a challenge for global health security, rendering many previously successful classes of antibiotics useless. Unfortunately, this also includes glycopeptide antibiotics (GPAs), such as vancomycin an
Externí odkaz:
https://doaj.org/article/1482fb7f89fb40ec97c01c50e7d1fbd1
Autor:
Roman Makitrynskyy, Bohdan Ostash, Olga Tsypik, Yuriy Rebets, Emma Doud, Timothy Meredith, Andriy Luzhetskyy, Andreas Bechthold, Suzanne Walker, Victor Fedorenko
Publikováno v:
Open Biology, Vol 3, Iss 10 (2013)
Unlike the majority of actinomycete secondary metabolic pathways, the biosynthesis of peptidoglycan glycosyltransferase inhibitor moenomycin in Streptomyces ghanaensis does not involve any cluster-situated regulators (CSRs). This raises questions abo
Externí odkaz:
https://doaj.org/article/33c1024c37604b4ea5d5b655eba1b955
Autor:
Oleksandr, Yushchuk, Kseniia, Zhukrovska, Bohdan, Ostash, Victor, Fedorenko, Flavia, Marinelli
Publikováno v:
International journal of molecular sciences. 23(24)
Glycopeptide antibiotics (GPAs) are among the most clinically successful antimicrobials. GPAs inhibit cell-wall biosynthesis in Gram-positive bacteria via binding to lipid II. Natural GPAs are produced by various actinobacteria. Being themselves Gram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d298af388330287f31861fb15cc3b59
https://pubmed.ncbi.nlm.nih.gov/36555354
https://pubmed.ncbi.nlm.nih.gov/36555354
Publikováno v:
Genes. 13(11)
Clinically relevant glycopeptide antibiotics remain among the most successful classes of natural antibacterials. This success, however, is endangered by the spread of glycopeptide resistance genes, also known as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a81e7754ababe16e22950e800f1908ff
https://pubmed.ncbi.nlm.nih.gov/36360197
https://pubmed.ncbi.nlm.nih.gov/36360197