Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Victor E. Laubach"'
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract The success of lung transplantation is limited by the high rate of primary graft dysfunction due to ischemia-reperfusion injury (IRI). Lung IRI is characterized by a robust inflammatory response, lung dysfunction, endothelial barrier disrupt
Externí odkaz:
https://doaj.org/article/fbd37829100a471980e44bfbb336bf22
Autor:
Zdravka Daneva, Yen‐Lin Chen, Huy Q. Ta, Vamsi Manchikalapudi, Abhishek Bazaz, Victor E. Laubach, Swapnil K. Sonkusare
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 1, Pp n/a-n/a (2023)
Abstract Endothelial cells (ECs) from small pulmonary arteries (PAs) release nitric oxide (NO) and prostacyclin, which lower pulmonary arterial pressure (PAP). In pulmonary hypertension (PH), the levels of endothelium‐derived NO and prostacyclin ar
Externí odkaz:
https://doaj.org/article/ed72a83138984a83b11cf07c8e9401ae
Publikováno v:
Clinical and Translational Medicine, Vol 8, Iss 1, Pp 1-11 (2019)
Abstract Chronic obstructive pulmonary disease (COPD) is expected to climb on the podium of the leading causes of mortality worldwide in the upcoming decade. Clinical diagnosis of COPD has classically relied upon detecting irreversible airflow obstru
Externí odkaz:
https://doaj.org/article/51462545ee8543d8b9a68f6239d89dfc
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Imaging holds an important role in the diagnosis of lung diseases. Along with clinical tests, noninvasive imaging techniques provide complementary and valuable information that enables a complete differential diagnosis. Various novel molecul
Externí odkaz:
https://doaj.org/article/adf3aea10c234edcb5e6c640ea3b0f60
Autor:
Matthew L. Stone, Yunge Zhao, J. Robert Smith, Mark L. Weiss, Irving L. Kron, Victor E. Laubach, Ashish K. Sharma
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Lung ischemia-reperfusion (IR) injury after transplantation as well as acute shortage of suitable donor lungs are two critical issues impacting lung transplant patients. This study investigates the anti-inflammatory and immunomodu
Externí odkaz:
https://doaj.org/article/7f57727a2fc541609e977609827c2648
Autor:
Eric J. Charles, MD, PhD, J. Hunter Mehaffey, MD, MSc, Mary E. Huerter, MD, Ashish K. Sharma, PhD, Mark H. Stoler, MD, Mark E. Roeser, MD, Dustin M. Walters, MD, Curtis G. Tribble, MD, Irving L. Kron, MD, Victor E. Laubach, PhD
Publikováno v:
Transplantation Direct, Vol 4, Iss 12, p e405 (2018)
Background. Increased utilization of donation after circulatory death (DCD) lungs may help alleviate the supply/demand mismatch between available donor organs and lung transplant candidates. Using an established porcine DCD model, we sought to determ
Externí odkaz:
https://doaj.org/article/51671e5f44e14dfea2b48e1ff42bfc59
Autor:
Zdravka Daneva, Matteo Ottolini, Yen Lin Chen, Eliska Klimentova, Maniselvan Kuppusamy, Soham A Shah, Richard D Minshall, Cheikh I Seye, Victor E Laubach, Brant E Isakson, Swapnil K Sonkusare
Publikováno v:
eLife, Vol 10 (2021)
Pannexin 1 (Panx1), an ATP-efflux pathway, has been linked with inflammation in pulmonary capillaries. However, the physiological roles of endothelial Panx1 in the pulmonary vasculature are unknown. Endothelial transient receptor potential vanilloid
Externí odkaz:
https://doaj.org/article/4e52c48d21c241c0a4496dbc4db01f8d
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 165:e5-e20
Acute respiratory distress syndrome represents the devastating result of acute lung injury, with high mortality. Limited methods are available for rehabilitation of lungs affected by acute respiratory distress syndrome. Our laboratory has demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3ec3fe15e31db344df4ed90f10ad2f
https://doi.org/10.1016/j.jtcvs.2022.04.005
https://doi.org/10.1016/j.jtcvs.2022.04.005
Autor:
Curtis C. Harris, Robert H. Wiltrout, Victor E. Laubach, Eilene Gruys, Timothy Back, Jonathan Weiss, Diana Haines, Draginja Djurickovic, Ewy Mathe, Giang Nguyen, Jonathan Schwank, Mark Bernard, Anne B. Hofseth, Leah Mechanic, Glenwood E. Trivers, Lorne J. Hofseth, Jeffery Subleski, Peijun He, S. Perwez Hussain
Nitric oxide (NO•), an important signaling molecule and a component of inflammatory response, is involved in tumorigenesis. However, the quantity of NO• and the cellular microenvironment influences the role of NO• in tumor development. We used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9549de40087fac6fdd5f81ff34f8bba
https://doi.org/10.1158/0008-5472.c.6497316
https://doi.org/10.1158/0008-5472.c.6497316
Autor:
Curtis C. Harris, Draginja Djurickovic, Robert H. Wiltrout, Victor E. Laubach, Diana Haines, Lynnette Shorts, Jeffrey Subleski, Weidong Jiang, Saira Doja, Leah E. Mechanic, Irfan Shaikh, Peijun He, Lorne J. Hofseth, Glennwood E. Trivers, S. Perwez Hussain
Supplementary Figure 2 from Nitric Oxide, a Mediator of Inflammation, Suppresses Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee712ae08414736519ce6f60471c834
https://doi.org/10.1158/0008-5472.22363457
https://doi.org/10.1158/0008-5472.22363457