Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Victor E Alvarez"'
Autor:
Satish Kumar Nemani, Silvio Notari, Ignazio Cali, Victor E Alvarez, Diane Kofskey, Mark Cohen, Robert A. Stern, Brian Appleby, Joseph Abrams, Lawrence Schonberger, Ann McKee, Pierluigi Gambetti
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with repetitive traumatic brain injury (TBI). CTE is generally found in athletes participating in contact sports and military personnel exposed to explosive bla
Externí odkaz:
https://doaj.org/article/1fe87befe49f4fa68e43dcf39d4af548
Autor:
Jonathan D Cherry, Thor D Stein, Yorghos Tripodis, Victor E Alvarez, Bertrand R Huber, Rhoda Au, Patrick T Kiernan, Daniel H Daneshvar, Jesse Mez, Todd M Solomon, Michael L Alosco, Ann C McKee
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185541 (2017)
CCL11, a protein previously associated with age-associated cognitive decline, is observed to be increased in the brain and cerebrospinal fluid (CSF) in chronic traumatic encephalopathy (CTE) compared to Alzheimer's disease (AD). Using a cohort of 23
Externí odkaz:
https://doaj.org/article/cec6bb8d3d1f428a8d1bd367ff7ef88c
Autor:
Grace A. Rosen, Daniel Kirsch, Raymond Nicks, Hunter Kelley, Rebecca Mathias, Kerry A. Cormier, Caroline A. Kubilus, Bryan Dec, Thor D. Stein, Victor E. Alvarez, Michael L. Alosco, Ann C. McKee, Bertrand R. Huber
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Postmortem human brain tissue is a critical resource for studying neurodegenerative disease, providing critical insights into cellular morphology, pathology, and network connectivity. To improve standard microscopy and enable high-resolution, three-d
Externí odkaz:
https://doaj.org/article/5196c8fe3c9443aaa0ad2245589b33e4
Autor:
Michael L. Alosco, Micaela White, Carter Bell, Farwa Faheem, Yorghos Tripodis, Eukyung Yhang, Zachary Baucom, Brett Martin, Joseph Palmisano, Kristen Dams-O’Connor, John F. Crary, Lee E. Goldstein, Douglas I. Katz, Brigid Dwyer, Daniel H. Daneshvar, Christopher Nowinski, Robert C. Cantu, Neil W. Kowall, Robert A. Stern, Victor E. Alvarez, Bertrand Russell Huber, Thor D. Stein, Ann C. McKee, Jesse Mez
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-19 (2024)
Abstract Background Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease characterized by hyperphosphorylated tau (p-tau) accumulation. The clinical features associated with CTE pathology are unclear. In brain donors with autopsy-con
Externí odkaz:
https://doaj.org/article/65a7290a4fbd418a87daa2a3b7d13138
Autor:
Ragini Phansalkar, Vanessa S. Goodwill, Jeffrey J. Nirschl, Chiara De Lillo, Jihee Choi, Elizabeth Spurlock, David G. Coughlin, Donald Pizzo, Christina J. Sigurdson, Annie Hiniker, Victor E. Alvarez, Ann C. Mckee, Jonathan H. Lin
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-10 (2023)
Abstract Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with repetitive head trauma. Brain pathology in CTE is characterized by neuronal loss, gliosis, and a distinctive pattern of neuronal accumulation of hyper-phos
Externí odkaz:
https://doaj.org/article/612dc488fe0f423f8daedf3b82d74059
Autor:
Grace Rosen, Daniel Kirsch, Sarah Horowitz, Jonathan D. Cherry, Raymond Nicks, Hunter Kelley, Madeline Uretsky, Kevin Dell’Aquila, Rebecca Mathias, Kerry A. Cormier, Caroline A. Kubilus, Jesse Mez, Yorghos Tripodis, Thor D. Stein, Victor E. Alvarez, Michael L. Alosco, Ann C. McKee, Bertrand R. Huber
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts (RHI) and characterized by perivascular accumulations of hyperphosphorylated tau protein (p-tau) at the depths of the c
Externí odkaz:
https://doaj.org/article/4531f0936a6544d6a12ec9a3e4959e5f
Autor:
Daniel H. Daneshvar, Evan S. Nair, Zachary H. Baucom, Abigail Rasch, Bobak Abdolmohammadi, Madeline Uretsky, Nicole Saltiel, Arsal Shah, Johnny Jarnagin, Christine M. Baugh, Brett M. Martin, Joseph N. Palmisano, Jonathan D. Cherry, Victor E. Alvarez, Bertrand R. Huber, Jennifer Weuve, Christopher J. Nowinski, Robert C. Cantu, Ross D. Zafonte, Brigid Dwyer, John F. Crary, Lee E. Goldstein, Neil W. Kowall, Douglas I. Katz, Robert A. Stern, Yorghos Tripodis, Thor D. Stein, Michael D. McClean, Michael L. Alosco, Ann C. McKee, Jesse Mez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy associated with repetitive head impacts (RHI), but the components of RHI exposure underlying this relationship are unclear. We create a position exposure matrix (PEM), c
Externí odkaz:
https://doaj.org/article/129e856278dd423e88ea46775ea88b9b
Autor:
Katharine J. Babcock, Bobak Abdolmohammadi, Patrick T. Kiernan, Ian Mahar, Jonathan D. Cherry, Victor E. Alvarez, Lee E. Goldstein, Thor D. Stein, Ann C. McKee, Bertrand R. Huber
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Exposure to military blast and repetitive head impacts (RHI) in contact sports is associated with increased risk of long-term neurobehavioral sequelae and cognitive deficits, and the neurodegenerative disease chronic traumatic encephalopathy
Externí odkaz:
https://doaj.org/article/3671b8af5d384f5184db303fb11dbedd
Autor:
Katherine W. Turk, Alexandra Geada, Victor E. Alvarez, Weiming Xia, Jonathan D. Cherry, Raymond Nicks, Gaoyuan Meng, Sarah Daley, Yorghos Tripodis, Bertrand R. Huber, Andrew E. Budson, Brigid Dwyer, Neil W. Kowall, Robert C. Cantu, Lee E. Goldstein, Douglas I. Katz, Robert A. Stern, Michael L. Alosco, Jesse Mez, Ann C. McKee, Thor D. Stein
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Cerebrospinal fluid (CSF) tau and beta-amyloid levels in chronic traumatic encephalopathy (CTE), a disease which can be clinically indistinguishable from Alzheimer’s disease (AD), are largely unknown. We examined postmortem CSF
Externí odkaz:
https://doaj.org/article/4f7f418230ce468aace772cfd97ce8e6
Autor:
Sheila T. Nagamatsu, Gregory Rompala, Yasmin L. Hurd, Diana L. Núñez-Rios, Janitza L. Montalvo-Ortiz, Traumatic Stress Brain Research Group, Victor E. Alvarez, David Benedek, Alicia Che, Dianne A. Cruz, David A. Davis, Matthew J. Girgenti, Ellen Hoffman, Paul E. Holtzheimer, Bertrand R. Huber, Alfred Kaye, John H. Krystal, Adam T. Labadorf, Terence M. Keane, Mark W. Logue, Ann McKee, Brian Marx, Deborah Mash, Mark W. Miller, Crystal Noller, JM-O, William K. Scott, Paula Schnurr, Thor Stein, Robert Ursano, Douglas E. Williamson, Erika J. Wolf, Keith A. Young
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2023)
IntroductionDNA methylation (DNAm), an epigenetic mechanism, has been associated with opioid use disorder (OUD) in preclinical and human studies. However, most of the studies have focused on DNAm at CpG sites. DNAm at non-CpG sites (mCpHs, where H in
Externí odkaz:
https://doaj.org/article/8e534560e2b9492589d5919efc931441