Genetic glucocorticoid receptor variants differ between ethnic groups but do not explain variation in age of diabetes onset, metabolic and inflammation parameters in patients with type 2 diabetes

Autor: Mohamed Ahdi, Maaike C. Gerards, Paul H.M. Smits, Eelco W. Meesters, Dees P. M. Brandjes, Max Nieuwdorp, Victor E. A. Gerdes

Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)

AimsThe effect of excess glucocorticoid receptor (GR) stimulation through glucocorticoid medication or cortisol on glucose metabolism is well established. There are genetic GR variants that result in increased or decreased GR stimulation. We aimed to

Externí odkaz: https://doaj.org/article/38b7215b17ec40de8bd0933d87eb576c

Cardiovascular risk assessment in periodontitis patients and controls using the European Systematic COronary Risk Evaluation (SCORE) model. A pilot study.

Autor: Madeline X. F. Kosho, Alexander R. E. Verhelst, Wijnand J. Teeuw, Victor E. A. Gerdes, Bruno G. Loos

Publikováno v: Frontiers in Physiology, Vol 13 (2023)

Aim: To investigate the use of the European SCORE model in a dental setting by exploring the frequency of a ‘high’ and ‘very high’ 10-year CVD mortality risk in patients with and without periodontitis. The secondary aim was to investigate the

Externí odkaz: https://doaj.org/article/1cada50d8246407e80790584ffb4a247

Ursodeoxycholic Acid Use After Bariatric Surgery

Autor: Maimoena S. S. Guman, Sylke Haal, Yair I. Z. Acherman, Arnold W. L. van de Laar, Max Nieuwdorp, Rogier P. Voermans, Victor E. A. Gerdes

Publikováno v: Guman, M S S, Haal, S, Acherman, Y I Z, van de Laar, A W L, Nieuwdorp, M, Voermans, R P & Gerdes, V E A 2023, ' Ursodeoxycholic Acid Use After Bariatric Surgery : Effects on Metabolic and Inflammatory Blood Markers ', Obesity Surgery, vol. 33, no. 6, pp. 1773-1781 . https://doi.org/10.1007/s11695-023-06581-8
Obesity surgery, 33(6), 1773-1781. Springer New York
Obesity Surgery, 33(6), 1773-1781. Springer New York

Background In addition to the reduction of symptomatic gallstone disease, ursodeoxycholic acid (UDCA) might also have beneficial metabolic effects after bariatric surgery. We examined the impact of UDCA on liver enzymes, hemoglobin A1c (HbA1c), lipid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa466351df2e27ad585cb530c81af71
http://www.scopus.com/inward/record.url?scp=85153342206&partnerID=8YFLogxK

Prevalence of Periodontal Disease among Patients at the Outpatient Clinic of Internal Medicine in an Academic Hospital in The Netherlands

Autor: Thomas J. T. Leung, Nina Nijland, Victor E. A. Gerdes, Bruno G. Loos

Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 20; Pages: 6018
Leung, T J T, Nijland, N, Gerdes, V E A & Loos, B G 2022, ' Prevalence of Periodontal Disease among Patients at the Outpatient Clinic of Internal Medicine in an Academic Hospital in The Netherlands : A Cross-Sectional Pilot Study ', Journal of Clinical Medicine, vol. 11, no. 20, 6018, pp. 1-13 . https://doi.org/10.3390/jcm11206018
Journal of clinical medicine, 11(20):6018. Multidisciplinary Digital Publishing Institute (MDPI)
Journal of Clinical Medicine, 11(20):6018, 1-13. MDPI AG
Leung, T J T, Nijland, N, Gerdes, V E A & Loos, B G 2022, ' Prevalence of Periodontal Disease among Patients at the Outpatient Clinic of Internal Medicine in an Academic Hospital in The Netherlands : A Cross-Sectional Pilot Study ', Clinical Chemistry, vol. 11, no. 20, 6018 . https://doi.org/10.3390/jcm11206018
Clinical Chemistry, 11(20):6018

There is a worldwide increase in individuals suffering ≥2 chronic diseases (multimorbidity), and the cause of combinations of conditions remains largely unclear. This pilot study analysed the prevalence of periodontal disease (PD) among (multi)-mor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e77dc6399a9dba326f0f3ea83b22c5
https://doi.org/10.3390/jcm11206018

The Role of Gut Microbiota and Its Produced Metabolites in Obesity, Dyslipidemia, Adipocyte Dysfunction, and Its Interventions

Autor: Max S. Z. Zwartjes, Victor E. A. Gerdes, Max Nieuwdorp

Publikováno v: Metabolites, Vol 11, Iss 8, p 531 (2021)

Obesity is becoming an increasing problem worldwide and is often, but not invariably, associated with dyslipidemia. The gut microbiota is increasingly linked to cardiovascular disease, nonalcoholic fatty liver disease, and type 2 diabetes mellitus. H

Externí odkaz: https://doaj.org/article/a54fa2496ab94f9eb856c3c85021dce7