Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Victor C Gan"'
Autor:
Emily K Rowe, Yee-Sin Leo, Joshua G X Wong, Tun-Linn Thein, Victor C Gan, Linda K Lee, David C Lye
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 4, p e2777 (2014)
BACKGROUND/METHODS: To better understand dengue fever in the elderly, we compared clinical features, World Health Organization (WHO) dengue classification and outcomes between adult (
Externí odkaz:
https://doaj.org/article/1da895f2b6f7442782e00fcb720850a6
Autor:
Farhad F Vasanwala, Tun-Linn Thein, Yee-Sin Leo, Victor C Gan, Ying Hao, Linda K Lee, David C Lye
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2712 (2014)
BACKGROUND: Dengue is an important viral infection with different presentations. Predicting disease severity is important in triaging patients requiring hospital care. We aim to study the value of proteinuria in predicting the development of dengue h
Externí odkaz:
https://doaj.org/article/56e6fab21a7a4ca38bcf681a0d03ee2a
Autor:
Joshua G X Wong, Victor C Gan, Ee-Ling Ng, Yee-Sin Leo, Siew-Pang Chan, Robin Choo, David C Lye
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96514 (2014)
BACKGROUND:Pain is a prominent feature of acute dengue as well as a clinical criterion in World Health Organization guidelines in diagnosing dengue. We conducted a prospective cohort study to compare levels of pain during acute dengue between differe
Externí odkaz:
https://doaj.org/article/b144640edc6347c5bbd82b5856f45659
Autor:
Victor C Gan, Li-Kiang Tan, David C Lye, Kwoon-Yong Pok, Shi-Qi Mok, Rachel Choon-Rong Chua, Yee-Sin Leo, Lee-Ching Ng
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90037 (2014)
WHO recommendations for dengue diagnosis require laboratory facilities. Antibody-based rapid diagnostic tests (RDTs) have performed poorly, and clinical diagnosis remains the mainstay in dengue-endemic countries. We evaluated a combination antigen-an
Externí odkaz:
https://doaj.org/article/f15275fb9e5e45efbb755aa18cb41a87
Autor:
Tun-Linn Thein, Yee-Sin Leo, Dale A Fisher, Jenny G Low, Helen M L Oh, Victor C Gan, Joshua G X Wong, David C Lye
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81060 (2013)
OBJECTIVES: To identify demographic, clinical and laboratory risk factors for death due to dengue fever in adult patients in Singapore. METHODS: Multi-center retrospective study of hospitalized adult patients with confirmed dengue fever in Singapore
Externí odkaz:
https://doaj.org/article/28502406fa634a39a29b2b87714538f5
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 1, p e2023 (2013)
BACKGROUND: In 2009, the World Health Organization (WHO) proposed seven warning signs (WS) as criteria for hospitalization and predictors of severe dengue (SD). We assessed their performance for predicting dengue hemorrhagic fever (DHF) and SD in adu
Externí odkaz:
https://doaj.org/article/bbcd76ea5f354ad883d55957c56fcaf9
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60946 (2013)
BACKGROUND: Revised dengue guidelines were published by the World Health Organization (WHO) in 2009 addressing severe dengue cases not classified by dengue hemorrhagic fever (DHF) and shock syndrome (DSS). METHODS AND PRINCIPAL FINDINGS: We conducted
Externí odkaz:
https://doaj.org/article/cd48f42300614d89806651094196ca95
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 6, p e1676 (2012)
BACKGROUND: Elevation of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) is prominent in acute dengue illness. The World Health Organization (WHO) 2009 dengue guidelines defined AST or ALT ≥ 1000 units/liter (U/L) as a criterion
Externí odkaz:
https://doaj.org/article/c29bf85825e9445abed0fa88c17bedb0
Autor:
Shobana Balasingam, Annelies Wilder-Smith, Ying Xiu Toh, Yee Sin Leo, Sumathy Velumani, Sophia Archuleta, Katja Fink, Tun-Linn Thein, Victor C. Gan
Publikováno v:
Human Vaccines & Immunotherapeutics. 12:1265-1273
Globally, dengue virus (DENV) is one of the most widespread vector-borne viruses. Dengue disease affects populations in endemic areas and, increasingly, tourists who travel to these countries, but there is currently no approved vaccine for dengue. A
Autor:
Victor C. Gan, Li Kiang Tan, Joshua G. X. Wong, Kim Sung Lee, Chee Fu Yung, Lee Ching Ng, Yee Sin Leo, David C. Lye, Tun-Linn Thein
Publikováno v:
The American Journal of Tropical Medicine and Hygiene
Studies on serotype-specific features of dengue and disease severity on adults are limited. We prospectively recruited adult febrile patients without alternate diagnosis to dengue from April 2005 to December 2011. Outcomes were defined using both the