Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Victor Boyartchuk"'
Autor:
Simon Loevenich, Nicola P. Montaldo, Arthur Wickenhagen, Tatyana Sherstova, Barbara van Loon, Victor Boyartchuk, Marit W. Anthonsen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Human metapneumovirus (HMPV) is a pneumovirus that may cause severe respiratory disease in humans. HMPV infection has been found to increase susceptibility to bacterial superinfections leading to increased morbidity and mortality. The molecular mecha
Externí odkaz:
https://doaj.org/article/2f7c75507af942d99e8d201f9636c812
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The innate immune and host-protective responses to viruses, such as the airway pathogen human metapneumovirus (HMPV), depend on interferons (IFNs) that is induced through TANK-binding kinase 1 (TBK1) and IFN regulatory factors (IRFs). The transcripti
Externí odkaz:
https://doaj.org/article/871abc81d4ce4a8c9f5ca0bda60f47e8
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207374 (2018)
ROR family of nuclear receptor transcription factors forms nodes connecting metabolic and inflammatory signaling pathways. The RORα members of the family have intrinsic transcriptional activity and they are involved in both activation and repression
Externí odkaz:
https://doaj.org/article/468317c2fab046559eb9627cacc98bad
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 9, Pp 835-845 (2009)
Intrahepatic and extrahepatic metastases are common findings in hepatocellular carcinoma (HCC). Insulin-like growth factor 2 (IGF2) expression is frequently induced in HCC, and serum IGF2 levels correlate with the presence of extrahepatic metastases.
Externí odkaz:
https://doaj.org/article/f7c0a6a8f6e7481ead0fe8231e6c0099
Publikováno v:
PLoS Genetics, Vol 3, Iss 9, Pp 1587-1597 (2007)
Genetic makeup of the host plays a significant role in the course and outcome of infection. Inbred strains of mice display a wide range of sensitivities to Listeria monocytogenes infection and thus serve as a good model for analysis of the effect of
Externí odkaz:
https://doaj.org/article/37910bdda27e4e98beb51a1c32afcc58
Autor:
Dongning Pan, Chunxiao Mao, Tie Zou, Annie Y Yao, Marcus P Cooper, Victor Boyartchuk, Yong-Xu Wang
Publikováno v:
PLoS Genetics, Vol 8, Iss 6, p e1002761 (2012)
Hepatic gluconeogenesis is required for maintaining blood glucose homeostasis; yet, in diabetes mellitus, this process is unrestrained and is a major contributor to fasting hyperglycemia. To date, the impacts of chromatin modifying enzymes and chroma
Externí odkaz:
https://doaj.org/article/d47c185e8b77477d8fa2ea28919ccf70
Autor:
Michael S Rogers, Victor Boyartchuk, Richard M Rohan, Amy E Birsner, William F Dietrich, Robert J D'Amato
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35237 (2012)
Angiogenesis is the process by which new blood vessels are formed from existing vessels. Mammalian populations, including humans and mice, harbor genetic variations that alter angiogenesis. Angiogenesis-regulating gene variants can result in increase
Externí odkaz:
https://doaj.org/article/3788edd0b3a041e68f35fae8e3eba6ff
Publikováno v:
Frontiers in Immunology
The innate immune and host-protective responses to viruses, such as the airway pathogen human metapneumovirus (HMPV), depend on interferons (IFNs) that is induced through TANK-binding kinase 1 (TBK1) and IFN regulatory factors (IRFs). The transcripti
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207374 (2018)
PLoS ONE
PLoS ONE
ROR family of nuclear receptor transcription factors forms nodes connecting metabolic and inflammatory signaling pathways. The RORα members of the family have intrinsic transcriptional activity and they are involved in both activation and repression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::422734941d61501b434a669c05b23449
http://hdl.handle.net/11250/2587613
http://hdl.handle.net/11250/2587613
Autor:
Martina Severa, Stephen N. Waggoner, Israel F. Charo, Nancy D. Kim, Katherine A. Fitzgerald, Daniel R. Caffrey, Zhaozhao Jiang, Sabina A. Islam, Victor Boyartchuk, Evelyn A. Kurt-Jones, Andrew D. Luster, Glennice Bowen Ryan
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 192(5)
The transcriptional repressor B lymphocyte–induced maturation protein 1 (BLIMP1) is a master regulator of B and T cell differentiation. To examine the role of BLIMP1 in innate immunity, we used a conditional knockout (CKO) of Blimp1 in myeloid cell