Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Victor Ambros"'
Autor:
Alejandro Vasquez-Rifo, Isana Veksler-Lublinsky, Zhenyu Cheng, Frederick M. Ausubel, Victor Ambros
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-22 (2019)
Abstract Background Multicellular animals and bacteria frequently engage in predator-prey and host-pathogen interactions, such as the well-studied relationship between Pseudomonas aeruginosa and the nematode Caenorhabditis elegans. This study investi
Externí odkaz:
https://doaj.org/article/cff3b0c88685470cb08d9fb1bc6c9214
Autor:
Charles Nelson, Victor Ambros
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 3 (2021)
AbstractThe let-7Caenorhabditis eleganslet-7let-7let-7lin-41let-7CaenorhabditisC. elegans,let-7let-7Caenorhabditis sulstonilet-7-let-7let-7let-7let-7let-7-
Externí odkaz:
https://doaj.org/article/feaf0d264cc543d18d9b2ed4907e054b
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3000969 (2020)
Pathogens such as Pseudomonas aeruginosa advantageously modify animal host physiology, for example, by inhibiting host protein synthesis. Translational inhibition of insects and mammalian hosts by P. aeruginosa utilizes the well-known exotoxin A effe
Externí odkaz:
https://doaj.org/article/d7afeeb9e853428694912bb19ff89b38
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 5, Pp 1227-1237 (2016)
The double-stranded RNA-binding protein Staufen has been implicated in various posttranscriptional gene regulatory processes. Here, we demonstrate that the Caenorhabditis elegans homolog of Staufen, STAU-1, functionally interacts with microRNAs. Loss
Externí odkaz:
https://doaj.org/article/5c24c0341e9741d5a6901b0f9a828180
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004286 (2014)
microRNAs function in diverse developmental and physiological processes by regulating target gene expression at the post-transcriptional level. ALG-1 is one of two Caenorhabditis elegans Argonautes (ALG-1 and ALG-2) that together are essential for mi
Externí odkaz:
https://doaj.org/article/b5a9b49db15e4bfbb582fb2b5d87776c
Autor:
Victor Ambros
Publikováno v:
PLoS Genetics, Vol 6, Iss 3, p e1000853 (2010)
Externí odkaz:
https://doaj.org/article/bc09018d24c0401c939a8a34e7de2c9a
Publikováno v:
bioRxiv
MicroRNAs (miRNA) are endogenous non-coding RNAs important for post-transcriptional regulation of gene expression. miRNAs associate with Argonaute proteins to bind to the 3’ UTR of target genes and confer target repression. Recently, multiplede nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1af2fc72e78d8e7db4d40be758ee15
https://doi.org/10.1101/2023.04.06.535748
https://doi.org/10.1101/2023.04.06.535748
Publikováno v:
Cell reports. 39(4)
Base pairing of the seed region (g2-g8) is essential for microRNA targeting; however, the in vivo function of the 3' non-seed region (g9-g22) is less well understood. Here, we report a systematic investigation of the in vivo roles of 3' non-seed nucl
Publikováno v:
microPublication Biology
RNA-seq is widely used for the quantitative analysis of transcriptomes in the context of studies of gene expression and regulation (Mortazavi et al., 2008; Ozsolak and Milos, 2011; Wang et al., 2009). Generally, RNA-seq protocols employ poly(A) selec
Autor:
Sungwook, Choi, Victor, Ambros
Publikováno v:
Development (Cambridge, England). 146(5)
C. elegans heterochronic genes determine the timing of expression of specific cell fates in particular stages of developing larvae. However, their broader roles in coordinating developmental events across diverse tissues have been less well investiga