Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Victor A. Tron"'
Autor:
Lyn M. Duncan, Alexander J. Lazar, Artur Zembowicz, Christopher R. Shea, Raymond L. Barnhill, Pedram Gerami, Jane L. Messina, Birgitta Schmidt, Lorenzo Cerroni, Richard A. Scolyer, Martin G. Cook, Iwei Yeh, Daniela Mihic-Probst, Lori Lowe, Klaus J. Busam, Martin C. Mihm, Jeffrey Zhao, Sook Jung Yun, David E. Elder, Armita Bahrami, Daniela Massi, Sarah Benton, Victor A Tron, Michael W. Piepkorn, Arnaud de la Fouchardière, Xiaowei Xu, Michael T. Tetzlaff, Bin Zhang, Gilles Landman, Iva Johansson, Philip E. LeBoit
Publikováno v:
American Journal of Surgical Pathology. 45:1597-1605
Atypical Spitzoid melanocytic tumors are diagnostically challenging. Many studies have suggested various genomic markers to improve classification and prognostication. We aimed to assess whether next-generation sequencing studies using the Tempus xO
Publikováno v:
Journal of Cutaneous Medicine and Surgery. 22:435-438
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22828 (2011)
BACKGROUND: MicroRNAs (miRNAs, miRs) are small non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. MicroRNAs are dysregulated in cancer and may play essential roles in tumorigenesis. Additionally, miRNAs have b
Externí odkaz:
https://doaj.org/article/b4d0f0a5032041da9d489e24b6a1dd13
Autor:
Angela M Keuling, Kathleen E A Felton, Arabesque A M Parker, Majid Akbari, Susan E Andrew, Victor A Tron
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6651 (2009)
BACKGROUND: Malignant melanoma is resistant to almost all conventional forms of chemotherapy. Recent evidence suggests that anti-apoptotic proteins of the Bcl-2 family are overexpressed in melanoma and may contribute to melanoma's striking resistance
Externí odkaz:
https://doaj.org/article/67fceb5c748d40d49fbb9776b77726dd
Autor:
Jagdish Butany, Fiorella Calabrese, Zhaolin Xu, Hyun J. Lim, Pierre Fiset, Adnan Mansoor, Victor A Tron, Emina Torlakovic, Scott L. Boerner, Christian Couture, Hala El-Zimaity, Penny J. Barnes, Gabor Fischer, John Garratt, Sinchita Roy-Chowdhuri, C. Blake Gilks, Lisa Manning, Laurette Geldenhuys, Carol C Cheung, Gilbert Bigras, H. Wang, Catherine Ross, Marius Ilie, Jean Deschenes, Alan Spatz, Robert H. Riddell, Ming-Sound Tsao, Paul E. Swanson, Diana N. Ionescu
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology
Supplemental Digital Content is available in the text.
Since 2014, programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) checkpoint inhibitors have been approved by various regulatory agencies for the treatment of multipl
Since 2014, programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) checkpoint inhibitors have been approved by various regulatory agencies for the treatment of multipl
Autor:
Victor A. Tron, Ricardo Vidal, Harriet Feilotter, Xiao Zhang, Karan J. Abraham, Geneviève C. Paré
Publikováno v:
The American Journal of Pathology. 186:1025-1035
Dysfunction of key miRNA pathways regulating basic cellular processes is a common driver of many cancers. However, the biological roles and/or clinical applications of such pathways in Merkel cell carcinoma (MCC), a rare but lethal cutaneous neuroend
Autor:
Adriana Taveira da Cruz, Fernando Andrade, Miriam Galvonas Jasiulionis, Victor A. Tron, Ana Luisa Pedroso Ayub, Ana Carolina Monteiro, André Fujita, Júlia A. Morata, Roseli da Silva Soares
Publikováno v:
Cancer Research. 79:2779-2779
In order to identify miRNAs able to distinguish melanoma patients with good or poor prognosis, the expression profile of a panel of miRNAs evaluated in primary melanoma samples from 65 patients was compared to clinicopathological data from these pati
Autor:
Victor A. Tron, Elizabeth Eisenhauer, Bingshu E. Chen, Karl Belanger, Naomi Hunder, Michael Smylie, Kerry J. Savage, Teresa M. Petrella, Suzanne Kamel-Reid, Richard Tozer, Linda Hagerman, Ralph Wong, Wendy Walsh
Publikováno v:
Journal of Clinical Oncology. 30:3396-3401
Purpose We report a multicenter phase II study of patients with metastatic melanoma (MM), evaluating the efficacy, toxicity, progression-free survival (PFS), immunogenicity, and biomarker profile of interleukin-21 (IL-21). Patients and Methods Patien
Autor:
Xiao Zhang, Victor A. Tron, Cindy Lentz, Xiaolong Yang, Marie Abi-Daoud, Jiamin Chen, Harriet Feilotter, Geneviève C. Paré
Publikováno v:
The American Journal of Pathology. 179:2162-2168
MicroRNAs play important roles in gene regulation, and their expression is frequently dysregulated in cancer cells. In a previous study, we reported that miR-193b represses cell proliferation and regulates cyclin D1 in melanoma cells, suggesting that
Autor:
Xiaolong Yang, Cherif Garady, Dulcie Lai, Jiamin Chen, Harriet Feilotter, Victor A. Tron, Xiao Zhang, Geneviève C. Paré, Joshua G. Pemberton
Publikováno v:
The American Journal of Pathology. 176:2520-2529
Cutaneous melanoma is an aggressive form of human skin cancer characterized by high metastatic potential and poor prognosis. To better understand the role of microRNAs (miRNAs) in melanoma, the expression of 470 miRNAs was profiled in tissue samples