Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Victor A. Shashilov"'
Autor:
Victor A. Shashilov, Igor K. Lednev
Publikováno v:
Journal of Raman Spectroscopy. 40:1749-1758
Since the initial introduction of the basic concept almost twenty years ago, two-dimensional correlation spectroscopy (2DCoS) has become a popular analytical tool applicable to a broad range of science problems. Vibrational spectroscopy remains the m
Autor:
Igor K. Lednev, Victor A. Shashilov
Publikováno v:
Journal of the American Chemical Society. 130:309-317
The early stages of hen egg white lysozyme (HEWL) fibrillation were quantitatively characterized by two-dimensional correlation deep UV resonance Raman spectroscopy (2D-DUVRR) in terms of the sequential order of events and their characteristic times.
Autor:
Igor K. Lednev, Dmitri V. Zagorevski, Laura Fredriksen, Victor A. Shashilov, Ming Xu, Vladimir V. Ermolenkov
Publikováno v:
Protein Science. 16:815-832
Amyloid fibril depositions are associated with many neurodegenerative diseases as well as amyloidosis. The detailed molecular mechanism of fibrillation is still far from complete understanding. In our previous study of in vitro fibrillation of hen eg
Publikováno v:
Journal of Quantitative Spectroscopy and Radiative Transfer. 102:46-61
Latent variable analysis of deep UV resonance Raman spectra was demonstrated to be a powerful tool for characterizing protein secondary structural composition. Non-negative independent component analysis (ICA) and pure variable methods, such as stepw
Publikováno v:
Inorganic Chemistry. 45:3606-3612
The investigation of complex formation between a bicyclic diamide, a novel chelating agent for lanthanides and actinides, and lutetium in an acetonitrile solution is reported. A free ligand and its lutetium complexes showed weak, noncharacteristic ne
Publikováno v:
Methods (San Diego, Calif.). 52(1)
Here we report on novel quantitative approaches for protein structural characterization using deep UV resonance Raman (DUVRR) spectroscopy. Specifically, we propose a new method combining hydrogen-deuterium (HD) exchange and Bayesian source separatio
Publikováno v:
Journal of the American Chemical Society. 129(36)
Studying the structure of the amyloid fibril is important for understanding fibrillogenesis at a molecular level. Hydrogen−deuterium exchange deep ultraviolet resonance Raman (DUVRR) spectroscopy combined with advanced statistical analysis allowed
Publikováno v:
The journal of physical chemistry. A. 109(32)
Deep UV resonance Raman spectroscopy was used for characterizing ligand-metal ion complexes. The obtained results demonstrated a strong intrinsic sensitivity and selectivity of a Raman spectroscopic signature of a bicyclic diamide, a novel chelating
Publikováno v:
Journal of the American Chemical Society. 129:6972-6973
Amyloid fibril depositions are associated with many neurodegenerative diseases. The nucleation step of fibrillation remains poorly characterized as no experimental technique allows for direct monitoring of nucleus formation. A new method based on 2D-