Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Victor A. Ilyin"'
Publikováno v:
Журнал Сибирского федерального университета: Серия Биология, Vol 8, Iss 4, Pp 478-494 (2015)
There are many different methods and tools for data analysis in dendrochronology. Modeling is one of them. One of the main issues in modeling is a choice of the main factors. Сlimatic data (temperature and precipitation) are the most common and affo
Externí odkaz:
https://doaj.org/article/0c47a0421a054a9a8919f539b3071414
Autor:
Margarita I. Popkova, Victor A. Ilyin, Marina V. Fonti, Alexander V. Kirdyanov, Irina N. Koyupchenko, Valentina V. Fakhrutdinova, Jian-Guo Huang, Bao Yang, Vladimir V. Shishov
Publikováno v:
Dendrochronologia. 79:126089
Autor:
Marat A. Mukhamedyarov, Vyacheslav E. Semenov, Florian Nachon, José A. Dias, Tatiana N. Pashirova, L. F. Nurullin, Vasiliy M. Babaev, Patrick Masson, Victor I. Ilyin, Natalia Petrova, Sofya V. Lushchekina, Irina V. Zueva, Konstantin A. Petrov, Lucia Ya. Zakharova
Publikováno v:
Neuropharmacology. 155:131-141
Profound synaptic dysfunction contributes to early loss of short-term memory in Alzheimer's disease. This study was set up to analyze possible neuroprotective effects of two dual binding site inhibitors of acetylcholinesterase (AChE), a new 6-methylu
Publikováno v:
Amino Acids. 51:1093-1102
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. Since the 1970s, many studies have focused on the role of GABA in the mammalian peripheral nervous system, and particularly in the choline
Autor:
Oksana A. Lenina, Alexandra D. Kharlamova, Marina E. Sitdykova, Ayrat R. Nurtdinov, Victor I. Ilyin, Irina V. Zueva, Evgeny E. Nikolsky, Konstantin A. Petrov
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Non-selective inhibitors of cholinesterases (ChEs) are clinically used for treatment of myasthenia gravis (MG). While being generally safe, they cause numerous adverse effects including induction of hyperactivity of urinary bladder and intestines aff
Publikováno v:
Journal of Neuroscience Research. 93:309-320
Transient receptor potential vanilloid type 1 (TRPV1) channels are capable of detecting and integrating noxious stimuli and play an important role in nociceptor activation and sensitization. It has been demonstrated that oxidizing agents are capable
Autor:
Jae H. Park, Donald J. Kyle, Victor I. Ilyin, Gang Wu, Laszlo L. Musza, Paul R. Blake, Kevin P. Carlin
Publikováno v:
Journal of Medicinal Chemistry. 57:6623-6631
The aqueous solution structure of protoxin II (ProTx II) indicated that the toxin comprises a well-defined inhibitor cystine knot (ICK) backbone region and a flexible C-terminal tail region, similar to previously described NaSpTx III tarantula toxins
Publikováno v:
Journal of Peptide Science. 18:442-448
Protoxin II is biologically active peptide containing the inhibitory cystine knot motif. A synthetic version of the toxin was generated with standard Fmoc solid phase peptide synthesis. If N-methylmorpholine was used as a base during synthesis of the
Autor:
Kevin P. Carlin, Toshiyuki Kanemasa, Laykea Tafesse, Victor I. Ilyin, Gang Wu, Toshiyuki Asaki
Publikováno v:
Biophysical Journal. 108(2)
In addition to pain sensation, both thermal regulation and thermosensation are thought to be influenced by TRPV1 channel functioning. Involvement of TRPV1 in these latter physiological functions became clear during pharmaceutical development of selec
Autor:
Richard M. Woodward, Victor I. Ilyin, Kenneth J. Valenzano, Gregg Crumley, Shakira Olanrewaju, Elfrida R. Benjamin, Farhana Pruthi, Elena Kutlina
Publikováno v:
SLAS Discovery. 11:29-39
Voltage-gated sodium channels (NaChs) are relevant targets for pain, epilepsy, and a variety of neurological and cardiac disorders. Traditionally, it has been difficult to develop structure-activity relationships for NaCh inhibitors due to rapid chan