Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Victor Wee Lin Ng"'
Autor:
Gavin O. Jones, Yi Yan Yang, Victor Wee Lin Ng, Daniel J. Coady, Robert M. Waymouth, Hans W. Horn, Shrinivas Venkataraman, Haritz Sardon, Tak Shun Fung, James L. Hedrick
Publikováno v:
Journal of the American Chemical Society. 137:13851-13860
Aliphatic N-substituted functional eight-membered cyclic carbonates were synthesized from N-substituted diethanolamines by intramolecular cyclization. On the basis of the N-substituent, three major subclasses of carbonate monomers were synthesized (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb7596d691575180236e0f276cfd4cf
https://doi.org/10.1021/jacs.5b06355
https://doi.org/10.1021/jacs.5b06355
Autor:
Sangeetha Krishnamurthy, James L. Hedrick, Min-Han Tan, Shujun Gao, Yi Yan Yang, Victor Wee Lin Ng
Publikováno v:
Nanomedicine. 10:2819-2832
Aim: Phenformin-loaded micelles (Phen M) were used in combination with gemcitabine-loaded micelles (Gem M) to study their combined effect against H460 human lung cancer cells and cancer stem cells (CSCs) in vitro and in vivo. Materials & methods: Gem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063210946e7a17dbc34bc370a086af79
https://doi.org/10.2217/nnm.15.109
https://doi.org/10.2217/nnm.15.109
Autor:
Graham N. George, Victor Wee Lin Ng, Charles G. Young, David J. Nielsen, David J. Evans, Paul D. Smith, Christian J. Doonan, Craig Gourlay, Jonathan M. White
Publikováno v:
Inorganic Chemistry. 54:6386-6396
Reaction of Tp(iPr)Mo(VI)OS(OAr) with cobaltocene in toluene results in the precipitation of brown, microcrystalline oxosulfido-Mo(V) compounds, [CoCp2][Tp(iPr)Mo(V)OS(OAr)] (Cp(-) = η(5)-C5H5(-), Tp(iPr)(-) = hydrotris(3-isopropylpyrazol-1-yl)borat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb3cd0bb3d951d9d1751f6b50256b54
https://doi.org/10.1021/acs.inorgchem.5b00708
https://doi.org/10.1021/acs.inorgchem.5b00708
Publikováno v:
Macromolecules. 48:2006-2012
Ring-opening metathesis polymerization (ROMP) of methyl-N-(1-phenylethyl)-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylate (PhEtNNBE; (S) and racemic) was investigated employing six molybdenum and tungsten imido alkylidene initiators and two tungsten oxo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478d4f04da570655f231470d2d820e8c
https://doi.org/10.1021/acs.macromol.5b00264
https://doi.org/10.1021/acs.macromol.5b00264
Publikováno v:
Biomacromolecules. 16:465-475
Humanized vascular endothelial growth factor (VEGF) antibody (bevacizumab; Avastin) is a highly effective monoclonal antibody against metastatic colorectal cancer and several other advanced late stage cancers. However, limited aqueous solubility and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a4c00172fa3cad07d5c3900076a4fc
https://doi.org/10.1021/bm5015206
https://doi.org/10.1021/bm5015206
Autor:
Shrinivas Venkataraman, Eddy W. P. Tan, Yi Yan Yang, Victor Wee Lin Ng, James L. Hedrick, Jeremy P. K. Tan
Publikováno v:
Biomacromolecules. 18(1)
Introduction of hydrophilic components, particularly amines and zwitterions, onto a degradable polymer platform, while maintaining precise control over the polymer composition, has been a challenge. Recognizing the importance of these hydrophilic res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95016558f224c0d477bc063fe67e221b
https://pubmed.ncbi.nlm.nih.gov/28064501
https://pubmed.ncbi.nlm.nih.gov/28064501
Publikováno v:
Biomaterials. 35:9177-9186
Conventional cancer chemotherapy often fails as most anti-cancer drugs are not effective against drug-resistant cancer stem cells. These surviving cancer stem cells lead to relapse and metastasis. In this study, an anti-diabetic drug, phenformin, cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f251fb5679058ab611038f6d6cfe164c
https://doi.org/10.1016/j.biomaterials.2014.07.018
https://doi.org/10.1016/j.biomaterials.2014.07.018
Autor:
Jiayu Leong, Yi Yan Yang, Victor Wee Lin Ng, Zhi Xiang Voo, James L. Hedrick, Jeremy P. K. Tan
Publikováno v:
Macromolecules. 47:1285-1291
Synthetic polymeric antimicrobials have received enormous attention recently on the back of increasing multidrug-resistance microbes. While conventional small molecular antibiotics act on specific targets to inhibit microbe activities, macromolecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90987fea1a719cd8dd3e054b47df9832
https://doi.org/10.1021/ma402641p
https://doi.org/10.1021/ma402641p
Publikováno v:
Biomaterials. 35:1096-1108
In this study, thioridazine (THZ), which was reported to kill cancer stem cells, was used in a combination therapy with doxorubicin (DOX) to eradicate both cancer cells and DOX-resistant cancer stem cells to mitigate the reoccurrence of the disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237d2ef89854026fb290b70cbdc40369
https://doi.org/10.1016/j.biomaterials.2013.10.049
https://doi.org/10.1016/j.biomaterials.2013.10.049
Publikováno v:
Biomaterials. 34:10278-10286
Current antimicrobial strategies have mostly been developed to manage infections due to planktonic cells. However, microbes in their nature state will tend to exist by attaching to and growing on living and inanimate surfaces that result in the forma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee13ce924e8ae1b161149cc08b7c3dd4
https://doi.org/10.1016/j.biomaterials.2013.09.029
https://doi.org/10.1016/j.biomaterials.2013.09.029