Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Victor, Tarabykin"'
Autor:
Paraskevi Bessa, Andrew G. Newman, Kuo Yan, Theres Schaub, Rike Dannenberg, Denis Lajkó, Julia Eilenberger, Theresa Brunet, Kathrin Textoris-Taube, Emanuel Kemmler, Penghui Deng, Priyanka Banerjee, Ethiraj Ravindran, Robert Preissner, Marta Rosário, Victor Tarabykin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Disruption of neocortical circuitry and architecture in humans causes numerous neurodevelopmental disorders. Neocortical cytoarchitecture is orchestrated by various transcription factors such as Satb2 that control target genes during strict
Externí odkaz:
https://doaj.org/article/02cf61f24d4e426786cf42a073c8b12e
Autor:
Ekaterina Borisova, Andrew G. Newman, Marta Couce Iglesias, Rike Dannenberg, Theres Schaub, Bo Qin, Alexandra Rusanova, Marisa Brockmann, Janina Koch, Marieatou Daniels, Paul Turko, Olaf Jahn, David R. Kaplan, Marta Rosário, Takao Iwawaki, Christian M. T. Spahn, Christian Rosenmund, David Meierhofer, Matthew L. Kraushar, Victor Tarabykin, Mateusz C. Ambrozkiewicz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract The mammalian neocortex comprises an enormous diversity regarding cell types, morphology, and connectivity. In this work, we discover a post-transcriptional mechanism of gene expression regulation, protein translation, as a determinant of co
Externí odkaz:
https://doaj.org/article/66af00ce766642a5b9c7bd2aa0b9eb91
Autor:
Maria Gavrish, Angelina Kustova, Juan C. Celis Suescún, Paraskevi Bessa, Natalia Mitina, Victor Tarabykin
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2024)
The Corpus Callosum (CC) is a bundle of axons connecting the cerebral hemispheres. It is the most recent structure to have appeared during evolution of placental mammals. Its development is controlled by a very complex interplay of many molecules. In
Externí odkaz:
https://doaj.org/article/669977940ae74c0cbe7bde2fcaee9d3d
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract The aim of this study was to characterize expression of corticogenesis-related transcription factors BCL11B and SATB2 after brain ischemic lesion in the adult mice, and to analyze their correlation to the subsequent brain recovery. Ischemic
Externí odkaz:
https://doaj.org/article/96a771ee9dd5404986e33bc2ce7120f8
Autor:
Angela Pärn, Ditte Olsen, Jürgen Tuvikene, Mathias Kaas, Ekaterina Borisova, Mesut Bilgin, Mie Elhauge, Joachim Vilstrup, Peder Madsen, Mateusz C. Ambrozkiewicz, Roman U. Goz, Tõnis Timmusk, Victor Tarabykin, Camilla Gustafsen, Simon Glerup
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2023)
PCSK9 induces lysosomal degradation of the low-density lipoprotein (LDL) receptor (LDLR) in the liver, hereby preventing removal of LDL cholesterol from the circulation. Accordingly, PCSK9 inhibitory antibodies and siRNA potently reduce LDL cholester
Externí odkaz:
https://doaj.org/article/0dab2a5c70df4751af18ae27826dc208
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Transcriptional regulation is essential for the correct functioning of cells during development and in postnatal life. The basic Helix-loop-Helix (bHLH) superfamily of transcription factors is well conserved throughout evolution and plays critical ro
Externí odkaz:
https://doaj.org/article/b2cabd8331be4693a1f2bf2cc3e5530b
Autor:
Elijah D Lowenstein, Aleksandra Rusanova, Jonas Stelzer, Marc Hernaiz-Llorens, Adrian E Schroer, Ekaterina Epifanova, Francesca Bladt, Eser Göksu Isik, Sven Buchert, Shiqi Jia, Victor Tarabykin, Luis R Hernandez-Miranda
Publikováno v:
eLife, Vol 10 (2021)
The mature cerebellum controls motor skill precision and participates in other sophisticated brain functions that include learning, cognition, and speech. Different types of GABAergic and glutamatergic cerebellar neurons originate in temporal order f
Externí odkaz:
https://doaj.org/article/24f3885ee81b435fa971001cfc7200d9
Autor:
Stefan Meinke, Gesine Goldammer, A Ioana Weber, Victor Tarabykin, Alexander Neumann, Marco Preussner, Florian Heyd
Publikováno v:
eLife, Vol 9 (2020)
Minor and major spliceosomes control splicing of distinct intron types and are thought to act largely independent of one another. SR proteins are essential splicing regulators mostly connected to the major spliceosome. Here, we show that Srsf10 expre
Externí odkaz:
https://doaj.org/article/a5e4a712c4944de5ada55793e57744d3
Autor:
Dermot Harnett, Mateusz C. Ambrozkiewicz, Ulrike Zinnall, Alexandra Rusanova, Ekaterina Borisova, Amelie N. Drescher, Marta Couce-Iglesias, Gabriel Villamil, Rike Dannenberg, Koshi Imami, Agnieszka Münster-Wandowski, Beatrix Fauler, Thorsten Mielke, Matthias Selbach, Markus Landthaler, Christian M. T. Spahn, Victor Tarabykin, Uwe Ohler, Matthew L. Kraushar
Publikováno v:
Nature Structural and Molecular Biology
Translation modulates the timing and amplification of gene expression after transcription. Brain development requires uniquely complex gene expression patterns, but large-scale measurements of translation directly in the prenatal brain are lacking. W
Autor:
Paraskevi Bessa, Andrew G. Newman, Kuo Yan, Theres Schaub, Rike Dannenberg, Denis Lajkó, Julia Eilenberger, Theresa Brunet, Kathrin Textoris-Taube, Emanuel Kemmler, Priyanka Banerjee, Ethiraj Ravindran, Michael Mülleder, Robert Preissner, Rudolf Grosschedl, Marta Rosário, Victor Tarabykin
SUMMARYDisruption of neocortical circuitry and architecture in humans causes numerous neurodevelopmental disorders. Neocortical cytoarchitecture is orchestrated by various transcription factors such as Satb2 that control target genes during strict ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72cd1f7971a50ba583d32a971a432e77
https://doi.org/10.1101/2023.02.10.527998
https://doi.org/10.1101/2023.02.10.527998