Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Victor, Stastny"'
Autor:
Buse Eglenen-Polat, Ryan R. Kowash, Hai-Cheng Huang, Silvia Siteni, Mingrui Zhu, Kenian Chen, Matthew E. Bender, Ilgen Mender, Victor Stastny, Benjamin J. Drapkin, Prithvi Raj, John D. Minna, Lin Xu, Jerry W. Shay, Esra A. Akbay
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract There are few effective treatments for small cell lung cancer (SCLC) underscoring the need for innovative therapeutic approaches. This study focuses on exploiting telomerase, a critical SCLC dependency as a therapeutic target. A prominent ch
Externí odkaz:
https://doaj.org/article/d143811484044c1b88f499b5d0432d04
Autor:
Ling Cai, Hongyu Liu, Fang Huang, Junya Fujimoto, Luc Girard, Jun Chen, Yongwen Li, Yu-An Zhang, Dhruba Deb, Victor Stastny, Karine Pozo, Christin S. Kuo, Gaoxiang Jia, Chendong Yang, Wei Zou, Adeeb Alomar, Kenneth Huffman, Mahboubeh Papari-Zareei, Lin Yang, Benjamin Drapkin, Esra A. Akbay, David S. Shames, Ignacio I. Wistuba, Tao Wang, Jane E. Johnson, Guanghua Xiao, Ralph J. DeBerardinis, John D. Minna, Yang Xie, Adi F. Gazdar
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Ling Cai et al. used transcriptomic profiling data of healthy lung, patient-derived small cell lung cancer cell lines, xenografts, and primary tumors to examine a link between neuroendocrine (NE) signatures and immune gene expression. Their findings
Externí odkaz:
https://doaj.org/article/c88977f0af0c4f029def4e50d414f3bb
Autor:
Hans K. Ghayee, Yiling Xu, Heather Hatch, Richard Brockway, Asha S. Multani, Tongjun Gu, Wendy B. Bollag, Adina Turcu, William E. Rainey, Juilee Rege, Kazutaka Nanba, Vikash J. Bhagwandin, Fiemu Nwariaku, Victor Stastny, Adi F. Gazdar, Jerry W. Shay, Richard J. Auchus, Sergei G. Tevosian
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 584 (2022)
The human adrenal cortex is composed of distinct zones that are the main source of steroid hormone production. The mechanism of adrenocortical cell differentiation into several functionally organized populations with distinctive identities remains po
Externí odkaz:
https://doaj.org/article/6db15ebcdfba404f90c05358b2a3b4b8
Autor:
Demetra P. Kelenis, Kathia E. Rodarte, Rahul K. Kollipara, Karine Pozo, Shreoshi Pal Choudhuri, Kyle B. Spainhower, Sarah J. Wait, Victor Stastny, Trudy G. Oliver, Jane E. Johnson
Publikováno v:
Cancer Res
Genomic studies support the classification of small cell lung cancer (SCLC) into subtypes based on the expression of lineage-defining transcription factors ASCL1 and NEUROD1, which together are expressed in ∼86% of SCLC. ASCL1 and NEUROD1 activate
Autor:
Jane E. Johnson, Trudy G. Oliver, Victor Stastny, Sarah J. Wait, Kyle B. Spainhower, Shreoshi Pal Choudhuri, Karine Pozo, Rahul K. Kollipara, Kathia E. Rodarte, Demetra P. Kelenis
Supplementary Figure from Inhibition of Karyopherin β1-Mediated Nuclear Import Disrupts Oncogenic Lineage-Defining Transcription Factor Activity in Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f77480f7d86cec73f1e64d9bc5eff7f
https://doi.org/10.1158/0008-5472.22431816.v1
https://doi.org/10.1158/0008-5472.22431816.v1
Autor:
Jane E. Johnson, Trudy G. Oliver, Victor Stastny, Sarah J. Wait, Kyle B. Spainhower, Shreoshi Pal Choudhuri, Karine Pozo, Rahul K. Kollipara, Kathia E. Rodarte, Demetra P. Kelenis
Genomic studies support the classification of small cell lung cancer (SCLC) into subtypes based on the expression of lineage-defining transcription factors ASCL1 and NEUROD1, which together are expressed in ∼86% of SCLC. ASCL1 and NEUROD1 activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8470d5df0b24ad6cd9d25425597d5fa5
https://doi.org/10.1158/0008-5472.c.6513996
https://doi.org/10.1158/0008-5472.c.6513996
Autor:
Jane E. Johnson, Trudy G. Oliver, Victor Stastny, Sarah J. Wait, Kyle B. Spainhower, Shreoshi Pal Choudhuri, Karine Pozo, Rahul K. Kollipara, Kathia E. Rodarte, Demetra P. Kelenis
Supplementary Table from Inhibition of Karyopherin β1-Mediated Nuclear Import Disrupts Oncogenic Lineage-Defining Transcription Factor Activity in Small Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ff3a62d6b73cfa5452e03cfed347e4
https://doi.org/10.1158/0008-5472.22431810
https://doi.org/10.1158/0008-5472.22431810
Autor:
Adi F. Gazdar, John D. Minna, John K. Field, George Xinarianos, Triantafillos Liloglou, Jack A. Roth, Eugene Frenkel, Bogdan Czerniak, Ignacio I. Wistuba, Frederik B. Thunnissen, Clemens Prinsen, Yang Xie, Luc Girard, Naoki Okumura, Victor Stastny, Narayan Shivapurkar
Supplementary Figure 2 from Cytoglobin, the Newest Member of the Globin Family, Functions as a Tumor Suppressor Gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10300259c4cc667c7509a819f004a2c7
https://doi.org/10.1158/0008-5472.22376525.v1
https://doi.org/10.1158/0008-5472.22376525.v1
Autor:
Adi F. Gazdar, John D. Minna, John K. Field, George Xinarianos, Triantafillos Liloglou, Jack A. Roth, Eugene Frenkel, Bogdan Czerniak, Ignacio I. Wistuba, Frederik B. Thunnissen, Clemens Prinsen, Yang Xie, Luc Girard, Naoki Okumura, Victor Stastny, Narayan Shivapurkar
Supplementary Figure Legends 1-2 from Cytoglobin, the Newest Member of the Globin Family, Functions as a Tumor Suppressor Gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7767db4ed9779f4a558c0edbeefdcd89
https://doi.org/10.1158/0008-5472.22376522
https://doi.org/10.1158/0008-5472.22376522
Autor:
Adi F. Gazdar, John D. Minna, John K. Field, George Xinarianos, Triantafillos Liloglou, Jack A. Roth, Eugene Frenkel, Bogdan Czerniak, Ignacio I. Wistuba, Frederik B. Thunnissen, Clemens Prinsen, Yang Xie, Luc Girard, Naoki Okumura, Victor Stastny, Narayan Shivapurkar
Supplementary Figure 1 from Cytoglobin, the Newest Member of the Globin Family, Functions as a Tumor Suppressor Gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527b4e3a8952d33a9e4bfbe920ff5d15
https://doi.org/10.1158/0008-5472.22376528
https://doi.org/10.1158/0008-5472.22376528