Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Victor, Borda"'
Autor:
Bing Guo, Victor Borda, Roland Laboulaye, Michele D. Spring, Mariusz Wojnarski, Brian A. Vesely, Joana C. Silva, Norman C. Waters, Timothy D. O’Connor, Shannon Takala-Harrison
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Malaria genomic surveillance often estimates parasite genetic relatedness using metrics such as Identity-By-Decent (IBD), yet strong positive selection stemming from antimalarial drug resistance or other interventions may bias IBD-based esti
Externí odkaz:
https://doaj.org/article/7cae15b4cbd74ccc81153c6622534127
Autor:
Rennan Garcias Moreira, Julia Maria Saraiva‐Duarte, Alexandre Costa Pereira, Martha Sosa‐Macias, Carlos Galaviz‐Hernandez, Meddly Lesley Santolalla, Wagner C. S. Magalhães, Camila Zolini, Thiago Peixoto Leal, Zsolt Balázs, Adrián Llerena, Robert H. Gilman, José Geraldo Mill, Victor Borda, Heinner Guio, Timothy D. O’Connor, Eduardo Tarazona‐Santos, Fernanda Rodrigues‐Soares
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 6, Pp 1400-1405 (2022)
Abstract PDE4B (phosphodiesterase‐4B) has an important role in cancer and in pharmacology of some disorders, such as inflammatory diseases. Remarkably in Native Americans, PDE4B variants are associated with acute lymphoblastic leukemia (ALL) relaps
Externí odkaz:
https://doaj.org/article/30e45fe2f5a74ed1a2c2287f6df6d9e9
Autor:
Michel S. Naslavsky, Marilia O. Scliar, Guilherme L. Yamamoto, Jaqueline Yu Ting Wang, Stepanka Zverinova, Tatiana Karp, Kelly Nunes, José Ricardo Magliocco Ceroni, Diego Lima de Carvalho, Carlos Eduardo da Silva Simões, Daniel Bozoklian, Ricardo Nonaka, Nayane dos Santos Brito Silva, Andreia da Silva Souza, Heloísa de Souza Andrade, Marília Rodrigues Silva Passos, Camila Ferreira Bannwart Castro, Celso T. Mendes-Junior, Rafael L. V. Mercuri, Thiago L. A. Miller, Jose Leonel Buzzo, Fernanda O. Rego, Nathalia M. Araújo, Wagner C. S. Magalhães, Regina Célia Mingroni-Netto, Victor Borda, Heinner Guio, Carlos P. Rojas, Cesar Sanchez, Omar Caceres, Michael Dean, Mauricio L. Barreto, Maria Fernanda Lima-Costa, Bernardo L. Horta, Eduardo Tarazona-Santos, Diogo Meyer, Pedro A. F. Galante, Victor Guryev, Erick C. Castelli, Yeda A. O. Duarte, Maria Rita Passos-Bueno, Mayana Zatz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Whole genome sequencing (WGS) data on non-European and admixed individuals remains scarce. Here, the authors analyse WGS data from 1,171 admixed elderly Brazilians from a census cohort, characterising population-specific genetic variation and explori
Externí odkaz:
https://doaj.org/article/363cefb9d1d14e1f9adc1fe81f04cd3f
Autor:
Marla Mendes, Manjari Jonnalagadda, Shantanu Ozarkar, Flávia Carolina Lima Torres, Victor Borda Pua, Christopher Kendall, Eduardo Tarazona-Santos, Esteban J. Parra
Publikováno v:
PLoS ONE, Vol 17, Iss 8 (2022)
In this study, we present the results of a genome-wide scan for signatures of positive selection using data from four tribal groups (Kokana, Warli, Bhil, and Pawara) and two caste groups (Deshastha Brahmin and Kunbi Maratha) from West of the Maharash
Externí odkaz:
https://doaj.org/article/f1d966fc5002414bb9a1979a665860a6
Autor:
Ana Cecília Guimarães Alves, Natalie Mary Sukow, Gabriel Adelman Cipolla, Marla Mendes, Thiago P. Leal, Maria Luiza Petzl-Erler, Ricardo Lehtonen Rodrigues Souza, Ilíada Rainha de Souza, Cesar Sanchez, Meddly Santolalla, Douglas Loesch, Michael Dean, Moara Machado, Jee-Young Moon, Robert Kaplan, Kari E. North, Scott Weiss, Mauricio L. Barreto, M. Fernanda Lima-Costa, Heinner Guio, Omar Cáceres, Carlos Padilla, Eduardo Tarazona-Santos, Ignacio F. Mata, Elena Dieguez, Víctor Raggio, Andres Lescano, Vitor Tumas, Vanderci Borges, Henrique B. Ferraz, Carlos R. Rieder, Artur Schumacher-Schuh, Bruno L. Santos-Lobato, Pedro Chana-Cuevas, William Fernandez, Gonzalo Arboleda, Humberto Arboleda, Carlos E. Arboleda-Bustos, Timothy D. O’Connor, Marcia Holsbach Beltrame, Victor Borda
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
In adulthood, the ability to digest lactose, the main sugar present in milk of mammals, is a phenotype (lactase persistence) observed in historically herder populations, mainly Northern Europeans, Eastern Africans, and Middle Eastern nomads. As the
Externí odkaz:
https://doaj.org/article/83fade9eedf24b7d99f1452beb4bd4e7
Autor:
Fernanda S.G. Kehdy, Murilo Pita-Oliveira, Mariana M. Scudeler, Sabrina Torres-Loureiro, Camila Zolini, Rennan Moreira, Lucas A. Michelin, Isabela Alvim, Carolina Silva-Carvalho, Vinicius C. Furlan, Marla M. Aquino, Meddly L. Santolalla, Victor Borda, Giordano B. Soares-Souza, Luis Jaramillo-Valverde, Andres Vasquez-Dominguez, Cesar Sanchez Neira, Renato S. Aguiar, Ricardo A. Verdugo, Timothy D. O`Connor, Heinner Guio, Eduardo Tarazona-Santos, Thiago P. Leal, Fernanda Rodrigues-Soares
Publikováno v:
Genetics and Molecular Biology, Vol 44, Iss 1 suppl 1 (2021)
Abstract For human/SARS-CoV-2 interactome genes ACE2, TMPRSS2 and BSG, there is a convincing evidence of association in Asians with influenza-induced SARS for TMPRSS2-rs2070788, tag-SNP of the eQTL rs383510. This case illustrates the importance of po
Externí odkaz:
https://doaj.org/article/9a9091e7195a434fa921e6c8a94d2aab
Autor:
Victor Borda, Ronaldo da Silva Francisco Junior, Joseane B Carvalho, Guilherme L Morais, Átila Duque Rossi, Paula Pezzuto, Girlene S Azevedo, Bruno L Schamber-Reis, Elyzabeth A Portari, Adriana Melo, Maria Elisabeth L Moreira, Letícia C Guida, Daniela P Cunha, Leonardo Gomes, Zilton F M Vasconcelos, Fabio R Faucz, Amilcar Tanuri, Constantine A Stratakis, Renato S Aguiar, Cynthia Chester Cardoso, Ana Tereza Ribeiro de Vasconcelos
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009507 (2021)
Congenital Zika Syndrome (CZS) is a critical illness with a wide range of severity caused by Zika virus (ZIKV) infection during pregnancy. Life-threatening neurodevelopmental dysfunctions are among the most common phenotypes observed in affected newb
Externí odkaz:
https://doaj.org/article/95f436c15dc4409494eead58cabd59bd
Autor:
Andrés Julián Gutiérrez-Escobar, Billie Velapatiño, Victor Borda, Charles S. Rabkin, Eduardo Tarazona-Santos, Lilia Cabrera, Jaime Cok, Catherine C. Hooper, Helena Jahuira-Arias, Phabiola Herrera, Mehwish Noureen, Difei Wang, Judith Romero-Gallo, Bao Tran, Richard M. Peek, Douglas E. Berg, Robert H. Gilman, M. Constanza Camargo
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Region-specific Helicobacter pylori subpopulations have been identified. It is proposed that the hspAmerind subpopulation is being displaced from the Americans by an hpEurope population following the conquest. Our study aimed to describe the genomes
Externí odkaz:
https://doaj.org/article/b6b76ee877c3446495f39bc0a0397410
Autor:
Michel S. Naslavsky, Marilia O. Scliar, Guilherme L. Yamamoto, Jaqueline Yu Ting Wang, Stepanka Zverinova, Tatiana Karp, Kelly Nunes, José Ricardo Magliocco Ceroni, Diego Lima de Carvalho, Carlos Eduardo da Silva Simões, Daniel Bozoklian, Ricardo Nonaka, Nayane dos Santos Brito Silva, Andreia da Silva Souza, Heloísa de Souza Andrade, Marília Rodrigues Silva Passos, Camila Ferreira Bannwart Castro, Celso T. Mendes-Junior, Rafael L. V. Mercuri, Thiago L. A. Miller, Jose Leonel Buzzo, Fernanda O. Rego, Nathalia M. Araújo, Wagner C. S. Magalhães, Regina Célia Mingroni-Netto, Victor Borda, Heinner Guio, Carlos P. Rojas, Cesar Sanchez, Omar Caceres, Michael Dean, Mauricio L. Barreto, Maria Fernanda Lima-Costa, Bernardo L. Horta, Eduardo Tarazona-Santos, Diogo Meyer, Pedro A. F. Galante, Victor Guryev, Erick C. Castelli, Yeda A. O. Duarte, Maria Rita Passos-Bueno, Mayana Zatz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/ff914ecb35074c19bb66b71e9811e0de
Autor:
Mateus H Gouveia, Andrew W Bergen, Victor Borda, Kelly Nunes, Thiago P Leal, Martin D Ogwang, Edward D Yeboah, James E Mensah, Tobias Kinyera, Isaac Otim, Hadijah Nabalende, Ismail D Legason, Sununguko Wata Mpoloka, Gaonyadiwe George Mokone, Patrick Kerchan, Kishor Bhatia, Steven J Reynolds, Richard B Birtwum, Andrew A Adjei, Yao Tettey, Evelyn Tay, Robert Hoover, Ruth M Pfeiffer, Robert J Biggar, James J Goedert, Ludmila Prokunina-Olsson, Michael Dean, Meredith Yeager, M Fernanda Lima-Costa, Ann W Hsing, Sarah A Tishkoff, Stephen J Chanock, Eduardo Tarazona-Santos, Sam M Mbulaiteye
Publikováno v:
PLoS Genetics, Vol 15, Iss 3, p e1008027 (2019)
Populations in sub-Saharan Africa have historically been exposed to intense selection from chronic infection with falciparum malaria. Interestingly, populations with the highest malaria intensity can be identified by the increased occurrence of endem
Externí odkaz:
https://doaj.org/article/070f691a778f44458d9696507b27c0ce