Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Victoire Cardot"'
Autor:
Craig L Slingluff, Gina R Petroni, Todd Bauer, Nipun Merchant, Osama Rahma, Rawad Elias, Scott Rodig, Matthew H G Katz, Andressa Dias Costa, Brian M Wolpin, Stephanie K Dougan, Chee-Chee Stucky, Kathleen Pfaff, Gauri R Varadhachary, Victoire Cardot-Ruffino, Matthew J Reilley, Patrick Lenehan, Tanios S Bekaii-Saab, Jonathan Andrew Nowak
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Background Pancreatic ductal adenocarcinoma (PDAC) is a challenging target for immunotherapy because it has an immunosuppressive tumor microenvironment. Neoadjuvant chemoradiotherapy can increase tumor-infiltrating lymphocyte (TIL) density, which may
Externí odkaz:
https://doaj.org/article/9581129e54704c9a868c55f1b44e76c3
Autor:
Jennifer Wang, Michael Dougan, Elisa Bello, Marc Pelletier, Li Qiang, Stephanie Dougan, Victoire Cardot-Ruffino, Megan Hoffman, Lestat Ali, Jaime Ivan Castillo Silva, Ayantu Temesgen, Patrick Lenehan, Lauren Kageler, Giselle Uribe, Annan Yang, Andrew J Aguirre, Srivatsan Raghavan, Viviana Cremasco
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ff64778eaac041e6a7e1d1f59965cbcd
Autor:
Milena Muzzolini, Ismahane Belhabib, Victoire Cardot, Annemilaï Tijeras-Raballand, Cindy Neuzillet, Corinne Bousquet, Renato Micelli Lupinacci, Christine Jean
Publikováno v:
Acta Cirúrgica Brasileira, Vol 38 (2023)
ABSTRACT Purpose: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers with increasing incidence. Even if progress have been made, the five-year overall survival remains lower than 10%. There is a desperate need in therapeutic impr
Externí odkaz:
https://doaj.org/article/a0715e33106448db9dd6c1512e69f780
Autor:
Adrien Bertrand-Chapel, Cassandre Caligaris, Tanguy Fenouil, Clara Savary, Sophie Aires, Sylvie Martel, Paul Huchedé, Christelle Chassot, Véronique Chauvet, Victoire Cardot-Ruffino, Anne-Pierre Morel, Fabien Subtil, Kayvan Mohkam, Jean-Yves Mabrut, Laurie Tonon, Alain Viari, Philippe Cassier, Valérie Hervieu, Marie Castets, Alain Mauviel, Stéphanie Sentis, Laurent Bartholin
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
In pancreatic ductal adenocarcinoma cells and patient tissue, SMAD2/3 is shown to mediate oncogenic effects of TGF-β in the absence of SMAD4.
Externí odkaz:
https://doaj.org/article/a5f9ba19e67344f0bdaca45412920ce2
Autor:
Michael Dougan, James M Cleary, Benjamin Schlechter, Sarah Slater, Kimmie Ng, Brian M Wolpin, Stephanie K Dougan, Anuj K Patel, Nadine J McCleary, Douglas A Rubinson, Lauren K Brais, Peter C Enzinger, Thomas A Abrams, Matthew B Yurgelun, Victoire Cardot-Ruffino, Naima Bollenrucher, Luisa Delius, S Jennifer Wang, Joshua Remland, C Elizabeth Keheler, Keri M Sullivan, Leah H Biller, Kimberly Perez, Harshabad Singh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background Recombinant granulocyte colony-stimulating factor (G-CSF) is routinely administered for prophylaxis or treatment of chemotherapy-induced neutropenia. Chronic myelopoiesis and granulopoiesis in patients with cancer has been shown to induce
Externí odkaz:
https://doaj.org/article/ffb2b2c1043940efb1756d04927a4861
Autor:
Agnès Martin, Josiane Castells, Valentine Allibert, Andréa Emerit, Cindy Zolotoff, Victoire Cardot‐Ruffino, Yann S. Gallot, Barbara Vernus, Véronique Chauvet, Laurent Bartholin, Laurent Schaeffer, Anne‐Cécile Durieux, Christophe Hourdé, François B. Favier, Laetitia Mazelin, Damien Freyssenet
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1686-1703 (2022)
Abstract Background Cancer patients at advanced stages experience a severe depletion of skeletal muscle compartment together with a decrease in muscle function, known as cancer cachexia. Cachexia contributes to reducing quality of life, treatment eff
Externí odkaz:
https://doaj.org/article/7f4c031da44d40ad8a2fdd254a02185b
Autor:
Cécile Torregrosa, Frédéric Chorin, Eva Ester Molina Beltran, Cindy Neuzillet, Victoire Cardot-Ruffino
Publikováno v:
Cancers, Vol 14, Iss 21, p 5402 (2022)
Multidisciplinary supportive care, integrating the dimensions of exercise alongside oncological treatments, is now regarded as a new paradigm to improve patient survival and quality of life. Its impact is important on the factors that control tumor d
Externí odkaz:
https://doaj.org/article/3cf171b8079b4c5b96da34457b6db2f0
Autor:
Nicolas Chuvin, David F. Vincent, Roxane M. Pommier, Lindsay B. Alcaraz, Johann Gout, Cassandre Caligaris, Karam Yacoub, Victoire Cardot, Elodie Roger, Bastien Kaniewski, Sylvie Martel, Celia Cintas, Sophie Goddard-Léon, Amélie Colombe, Julie Valantin, Nicolas Gadot, Emilie Servoz, Jennifer Morton, Isabelle Goddard, Anne Couvelard, Vinciane Rebours, Julie Guillermet, Owen J. Sansom, Isabelle Treilleux, Ulrich Valcourt, Stéphanie Sentis, Pierre Dubus, Laurent Bartholin
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 4, Iss 2, Pp 263-282 (2017)
Background & Aims: Transforming growth factor beta (TGFβ) acts either as a tumor suppressor or as an oncogene, depending on the cellular context and time of activation. TGFβ activates the canonical SMAD pathway through its interaction with th
Externí odkaz:
https://doaj.org/article/e49cd12ee88d4e9a90e40577438a5e07
Autor:
Alexandra E Grier, Stephen Burleigh, Jaya Sahni, Courtnee A Clough, Victoire Cardot, Dongwook C Choe, Michelle C Krutein, David J Rawlings, Michael C Jensen, Andrew M Scharenberg, Kyle Jacoby
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Increasing demand for large-scale synthesis of in vitro transcribed (IVT) mRNA is being driven by the increasing use of mRNA for transient gene expression in cell engineering and therapeutic applications. An important determinant of IVT mRNA potency
Externí odkaz:
https://doaj.org/article/0765478c45c24feb9f2d7d51e87d648f
Autor:
Paul Eliezer Oberstein, Osama E. Rahma, Nina Beri, Amy C. Stoll-D'Astice, Anne-Marie Duliege, Emily Kawaler, Igor Dolgalev, Gregor Werba, Victoire Cardot-Ruffino, Naïma Böllenrücher, Saloney Nazeer, Matthew Squires, Dafna Bar-Sagi, Brian M. Wolpin, Stephanie Dougan, Diane M. Simeone
Publikováno v:
Journal of Clinical Oncology. 40:e16287-e16287
e16287 Background: Pancreatic ductal adenocarcinoma (PDA) has been refractory to therapeutic targeting of the immune microenvironment. In preclinical work, IL-1β was upregulated in PDA tumors, and in mouse models, IL-1β expression led to activation