Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vicky Torrano"'
Autor:
Tamara Tripic, Malcolm K. Brenner, Cecilia Barese, Daniel Y. Lee, Hao Liu, Adrian P. Gee, Helen E. Heslop, Vicky Torrano, Catherine M. Bollard, Stephen Gottschalk, Olga Dakhova, Owen A. O'Connor, Youli Zu, Cliona M. Rooney, Gianpietro Dotti, Conrad Russell Y. Cruz, Andrea N. Marcogliese, Meng-Fen Wu, George Carrum, Carlos A. Ramos
Publikováno v:
Journal of Clinical Oncology. 36:1128-1139
Purpose Transforming growth factor-β (TGF-β) production in the tumor microenvironment is a potent and ubiquitous tumor immune evasion mechanism that inhibits the expansion and function of tumor-directed responses; therefore, we conducted a clinical
Autor:
Enli Liu, Zhuyong Mei, Hao Liu, Rammurti T. Kamble, Bambi Grilley, Barbara Savoldo, Helen E. Heslop, Malcolm K. Brenner, Brandon Ballard, Huimin Zhang, Gianpietro Dotti, Olga Dakhova, Adrian P. Gee, George Carrum, Meng Fen Wu, Cliona M. Rooney, Vicky Torrano, Carlos A. Ramos
Publikováno v:
Journal of Clinical Investigation. 126:2588-2596
BACKGROUND. Treatment of B cell malignancies with adoptive transfer of T cells with a CD19-specific chimeric antigen receptor (CAR) shows remarkable clinical efficacy. However, long-term persistence of T cells targeting CD19, a pan–B cell marker, a
Autor:
Andrea M. Sheehan, Youli Zu, Elizabeth J. Shpall, Cliona M. Rooney, Barbara Pro, Stephanie Ku, Daniel Lee, George Carrum, Oumar Diouf, Malcolm K. Brenner, Meng Fen Wu, Hao Liu, Catherine M. Bollard, Adrian P. Gee, Luis Fayad, Stephen Gottschalk, Yasmin Hazrat, Carlos A. Ramos, Helen E. Heslop, Vicky Torrano
Publikováno v:
Journal of Clinical Oncology. 32:798-808
Purpose Tumor cells from approximately 40% of patients with Hodgkin or non-Hodgkin lymphoma express the type II latency Epstein-Barr virus (EBV) antigens latent membrane protein 1 (LMP1) and LMP2, which represent attractive targets for immunotherapy.
Autor:
G. Dotti, Mrinalini Bilgi, Cliona M. Rooney, Olga Dakhova, Zhuyong Mei, Helen E. Heslop, Carlos A. Ramos, Barbara Savoldo, Meng-Fen Wu, Adrian P. Gee, Bambi Grilley, Malcolm K. Brenner, Claudia Gerken, Vicky Torrano
Publikováno v:
Hematological Oncology. 37:168-168
Autor:
Cliona M. Rooney, Conrad Russell Y. Cruz, Patrick J. Hanley, Helen E. Heslop, Chrystal U. Louis, James A. Arce, Gianpietro Dotti, Yu Feng Lin, Malcolm K. Brenner, Barbara Savoldo, Hao Liu, Ann M. Leen, Catherine M. Bollard, Adrian P. Gee, Stephen Gottschalk, Vicky Torrano
Publikováno v:
Cytotherapy. 12:743-749
Background aims The Food and Drug Administration (FDA) currently recommends at least 4h of recipient monitoring after T cell infusions to detect early infusion reactions. Recent catastrophic reactions to ‘first-in-man' biologic agents have emphasiz
Autor:
Carlos A. Ramos, Adrian P. Gee, Minthran Ngo, Vicky Torrano, Lisa Rollins, Cliona M. Rooney, Catherine M. Bollard, Stephen Gottschalk, Jun Ando, Oumar Diouf, Natalia Lapteva, Helen E. Heslop, Ann M. Leen, Juan F. Vera, Serena K. Perna
Publikováno v:
Biology of Blood and Marrow Transplantation. 20(2)
Autor:
Catherine M. Bollard, Karen L. Hodgkin, Carlos A. Ramos, Helen E. Heslop, Shannon Inman, Sandhya Sharma, Birju Mehta, Fnu Spoorthi, Serena K. Perna, Vicky Torrano, Kurt C. Gunter, Rayne H. Rouce, Malcolm K. Brenner, Adrian P. Gee, Cliona M. Rooney, Natalia Lapteva, Benjamin Shin
Publikováno v:
Blood. 128:2990-2990
Up to 30 % of Hodgkin and non-Hodgkin lymphomas carry the Epstein Barr virus (EBV) genome and express the viral latency type 2 proteins EBNA-1, LMP-1, LMP-2 and BARF-1 in a pattern termed Type 2 latency. We have previously shown that Epstein-Barr vir
Autor:
Vicky Torrano, Rayne H. Rouce, M.K. Brenner, Adrian P. Gee, Serena K. Perna, Sandhya Sharma, C.M. Rooney, Natalia Lapteva, Helen E. Heslop, Carlos A. Ramos, Catherine M. Bollard
Publikováno v:
Cytotherapy. 18:S21
Autor:
Natalia Lapteva, Minhtran C. Ngo, Cliona M. Rooney, Catherine M. Bollard, Rayne H. Rouce, Serena K. Perna, Carlos A. Ramos, Ann M. Leen, Sandhya Sharma, Adrian P. Gee, Birju Mehta, Helen E. Heslop, Vicky Torrano
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts Up to ~40 % of Hodgkin and non-Hodgkin lymphomas carry the Epstein-Barr virus (EBV) genome and express type 2 viral latency proteins (T2LPs) EBNA-1, LMP-1, LMP-2 and BARF-1. EBV specific T cells (EBVSTs) can be generated from the bl
Autor:
Sandhya Sharma, Serena K. Perna, Vicky Torrano, Helen E. Heslop, Cliona M. Rooney, Rayne H. Rouce, Natalia Lapteva, Minhtran C. Ngo, Catherine M. Bollard, Carlos A. Ramos
Publikováno v:
Molecular Therapy. 23:S288
Up to 30% of Hodgkin and non-Hodgkin lymphomas carry the Epstein-Barr virus (EBV) genome and express the viral latency proteins EBNA1, LMP1, LMP2 and BARF1; a type 2 latency pattern of EBV gene expression. We previously reported that EBV-specific T-c