Výsledky vyhledávání - "Vicky Steubler"

Akademický článek

Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin

Autor: Sindhuja Gowrisankaran, Sébastien Houy, Johanna G. Peña del Castillo, Vicky Steubler, Monika Gelker, Jana Kroll, Paulo S. Pinheiro, Dirk Schwitters, Nils Halbsgut, Arndt Pechstein, Jan R. T. van Weering, Tanja Maritzen, Volker Haucke, Nuno Raimundo, Jakob B. Sørensen, Ira Milosevic

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)

Endophilins-A are conserved membrane-associated proteins required for endocytosis. Here, the authors report that endophilins-A also promote exocytosis of neurosecretory vesicles by coordinating priming and fusion through intersectin-1, independently

Externí odkaz: https://doaj.org/article/d12b951e45ac43b1b8a71db762ee3203

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Akademický článek

Capture of Dense Core Vesicles at Synapses by JNK-Dependent Phosphorylation of Synaptotagmin-4

Autor: Vinita Bharat, Michael Siebrecht, Katja Burk, Saheeb Ahmed, Carsten Reissner, Mahdokht Kohansal-Nodehi, Vicky Steubler, Markus Zweckstetter, Jonathan T. Ting, Camin Dean

Publikováno v: Cell Reports, Vol 21, Iss 8, Pp 2118-2133 (2017)

Delivery of neurotrophins and neuropeptides via long-range trafficking of dense core vesicles (DCVs) from the cell soma to nerve terminals is essential for synapse modulation and circuit function. But the mechanism by which transiting DCVs are captur

Externí odkaz: https://doaj.org/article/b2c8ae3ec17a450bba213c83aeb7b3f4

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Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism-like phenotype

Autor: David P. Wolfer, Lutz Slomianka, Susann Ludewig, Martin Korte, Kang Han, Dominique Fässler, Jakob von Engelhardt, Irmgard Amrein, Max Richter, Ulrike Müller, Michaela K Back, Susanne Erdinger, Vicky Steubler

Publikováno v: The EMBO Journal, 40 (12)
e107471
The EMBO journal
England
The EMBO Journal

The key role of APP for Alzheimer pathogenesis is well established. However, perinatal lethality of germline knockout mice lacking the entire APP family has so far precluded the analysis of its physiological functions for the developing and adult bra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9268a387c9aba6df8c81a779d2e18303
https://pubmed.ncbi.nlm.nih.gov/34188229

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