Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Vicky Pui‐Chi Tin"'
Autor:
Zhi‐Jie Xiao, Si‐Qi Wang, Jun‐Jiang Chen, Yun Li, Yuchen Jiang, Vicky Pui‐Chi Tin, Jia Liu, Huiyi Hu, Maria Pik Wong, Yihang Pan, Judy Wai Ping Yam
Publikováno v:
Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)
Abstract Tumor‐initiating cells (TICs) resilience and an immunosuppressive microenvironment are aggressive oncogenic phenotypes that contribute to unsatisfactory long‐term outcomes in lung adenocarcinoma (LUAD) patients. The molecular mechanisms
Externí odkaz:
https://doaj.org/article/e915842cedec452eb9539396b6763cea
NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma
Autor:
Zhi-Jie Xiao, Jing Liu, Si-Qi Wang, Yun Zhu, Xu-Yuan Gao, Vicky Pui-Chi Tin, Jing Qin, Jun-Wen Wang, Maria Pik Wong
Publikováno v:
eLife, Vol 6 (2017)
Tumor-initiating cells (TIC) are dynamic cancer cell subsets that display enhanced tumor functions and resilience to treatment but the mechanism of TIC induction or maintenance in lung cancer is not fully understood. In this study, we show the calciu
Externí odkaz:
https://doaj.org/article/1c68b7b949b346c6b5843405f58ee1a4
Autor:
Elaine Lai-Han Leung, Ronald R Fiscus, James W Tung, Vicky Pui-Chi Tin, Lik Cheung Cheng, Alan Dart-Loon Sihoe, Louis M Fink, Yupo Ma, Maria Pik Wong
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14062 (2010)
The cancer stem cell theory hypothesizes that cancers are perpetuated by cancer stem cells (CSC) or tumor initiating cells (TIC) possessing self-renewal and other stem cell-like properties while differentiated non-stem/initiating cells have a finite
Externí odkaz:
https://doaj.org/article/b7d9d6e2d503443f90a80470c24c8976
Autor:
Maria Pik Wong, Lap-Ping Chung, Lik-Cheung Cheng, Alan Dart-Loon Sihoe, Daniel Tsin-Tien Chua, Vicky Pui-Chi Tin, Elaine Lai-Han Leung, Issan Yee-San Tam
Supplementary Tables 1-2 from Double EGFR mutants containing rare EGFR mutant types show reduced in vitro response to gefitinib compared with common activating missense mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434301e3a2b5094ec13229a78fb023a0
https://doi.org/10.1158/1535-7163.22485179
https://doi.org/10.1158/1535-7163.22485179
Autor:
Maria Pik Wong, Lap-Ping Chung, Lik-Cheung Cheng, Alan Dart-Loon Sihoe, Daniel Tsin-Tien Chua, Vicky Pui-Chi Tin, Elaine Lai-Han Leung, Issan Yee-San Tam
Epidermal growth factor receptor (EGFR) mutations are common in lung adenocarcinomas, especially from nonsmoking women of Asian descent. We have previously shown EGFR mutations occur in >70% of lung adenocarcinoma from nonsmokers in our population wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df112e5abd3c413c350a3c0615138dd
https://doi.org/10.1158/1535-7163.c.6531815
https://doi.org/10.1158/1535-7163.c.6531815
Autor:
Jing Liu, Judy Wai Ping Yam, Vicky Pui-Chi Tin, Zhi-Jie Xiao, Yun Zhu, Maria Pik Wong, Si-Qi Wang, Jing Qin
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 6, Pp 1-13 (2020)
Cell Death and Disease, Vol 11, Iss 6, Pp 1-13 (2020)
Tumor initiating cells (TIC) of lung cancer are mainly induced by stress-related plasticity. Calcium/Calmodulin dependent protein kinase II alpha (CAMK2A) is a key calcium signaling molecule activated by exogenous and endogenous stimuli with effects
NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma
Autor:
Jing Liu, Junwen Wang, Xu Yuan Gao, Yun Zhu, Maria Pik Wong, Si-Qi Wang, Jing Qin, Vicky Pui-Chi Tin, Zhi-Jie Xiao
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Tumor-initiating cells (TIC) are dynamic cancer cell subsets that display enhanced tumor functions and resilience to treatment but the mechanism of TIC induction or maintenance in lung cancer is not fully understood. In this study, we show the calciu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d12cc9a7a785741f0e9b28c6cef3ca
Autor:
SK Wong, Junwen Wang, Ka Yan Ho, Jing Liu, Zhi-Jie Xiao, Maria Pik Wong, Vicky Pui-Chi Tin, Mai Har Sham
Publikováno v:
Oncotarget
// Jing Liu 1 , Zhijie Xiao 1 , Sunny Kit-Man Wong 1 , Vicky Pui-Chi Tin 1 , Ka-Yan Ho 1 , Junwen Wang 2 , Mai-Har Sham 2 , Maria Pik Wong 1 1 Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR China
Autor:
Lik-Cheung Cheng, Vicky Pui-Chi Tin, Joseph S. K. Au, Alan D. L. Sihoe, Sunny Kit Man Wong, Daisy Wing-Sze Wong, Lap-Ping Chung, Maria Pik Wong, Elaine Lai-Han Leung
Publikováno v:
Cancer. 117:2709-2718
BACKGROUND: The anaplastic lymphoma kinase (ALK) gene is involved frequently in chromosomal translocations, resulting in fusion genes with different partners found in various lymphoproliferative conditions. It was recently reported in nonsmall cell l