Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vicky L. Benson"'
Autor:
Marco Annandale, Yohanes Nursalim, Van Eyk Je, X. Li, Shiang Y. Lim, Chan Ej, Kim L. Powell, Parisa Koutsifeli, Robert G. Parton, Rajesh Katare, Claire L. Curl, Xueyan Hu, Rui-Ping Xiao, Aaron E. Robinson, Enzo R. Porrello, L.M.D. Delbridge, Koen Raedschelders, Terence J. O'Brien, James E. Hudson, L. J. Daniels, Antonia J.A. Raaijmakers, Johannes V Janssens, U. Varma, Rebecca H. Ritchie, Richard J. Mills, Vicky L. Benson, Roberta A. Gottlieb, Wendy T K Ip, Bell, David J. R. Taylor, Kimberley M. Mellor, Aleksandr Stotland, Chanchal Chandramouli, Regis R. Lamberts, Gabriel B. Bernasochi
SummaryDiabetic heart disease is highly prevalent and characterized by diastolic dysfunction. The mechanisms of diabetic heart disease are poorly understood and no targeted therapies are available. Here we show that the diabetic myocardium (type 1 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aee16cd88e4ec16dbf778c4ede38ae6a
https://doi.org/10.1101/2021.06.21.449174
https://doi.org/10.1101/2021.06.21.449174
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:1949-1959
Diabetic cardiomyopathy is a distinct pathology independent of co-morbidities such as coronary artery disease and hypertension. Diminished glucose uptake due to impaired insulin signaling and decreased expression of glucose transporters is associated
Autor:
Maria B. Grant, Samuel J. Adamson, Meidong Zhu, Ping Hu, Tailoi Chan-Ling, Frank Arfuso, Lynn C Shaw, Nicholas H. Hunt, Raj Devasahayam, Mohammad Nasir Uddin, Vicky L. Benson
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose We investigated the relationship between inflammation, neuronal loss, and expression of indoleamine 2, 3-dioxygenase (IDO) and quinolinic acid (QUIN) in the retina of subjects with type 1 diabetes (T1D) and type 2 diabetes (T2D) and in the re
SIRT1 Polymorphisms and Serum-Induced SIRT1 Protein Expression in Aging and Frailty: The CHAMP Study
Autor:
Shajjia Razi, Robert G. Cumming, David G. Le Couteur, Marina L. Kennerson, Vicky L. Benson, Rafael de Cabo, Aisling C. McMahon, Victoria C. Cogger, David J. Handelsman, Vasikaran Naganathan, Louise M. Waite, Vasant Hirani, Markus J. Seibel, Fiona M. Blyth
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 72(7)
The nutrient sensing protein, SIRT1 influences aging and nutritional interventions such as caloric restriction in animals, however, the role of SIRT1 in human aging remains unclear. Here, the role of SIRT1 single-nucleotide polymorphisms (SNPs) and s
Publikováno v:
Diabetes. 65(12)
A link between excess dietary sugar and cardiac disease is clearly evident and has been largely attributed to systemic metabolic dysregulation. Now a new paradigm is emerging, and a compelling case can be made that fructose-associated heart injury ma
Autor:
Vicky L. Benson, Rafael de Cabo, David J. Handelsman, Marina L. Kennerson, Robert G. Cumming, Vasi Naganathan, Fiona M. Blyth, Aisling C. McMahon, Markus J. Seibel, David G. Le Couteur
Circulating factors that have an effect on SIRT1 expression are influenced by caloric restriction. To determine the association between frailty and such circulating factors, we measured serum-induced SIRT1 expression from a nested cohort of frail (n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b2aa9b6469e2a02e50248d5ba6f459
https://europepmc.org/articles/PMC4007825/
https://europepmc.org/articles/PMC4007825/
Publikováno v:
Diabetesvascular disease research. 4(2)