Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Vicky Hannam"'
Autor:
Jim Hu, Gregory P. Downey, Rosetta Belcastro, Brent Steer, David R. Koehler, Martin Post, Yanxia Wen, Vicky Hannam, A. Keith Tanswell
Publikováno v:
Molecular Therapy. 4:58-65
We have developed an expression cassette for cystic fibrosis (CF) gene therapy using control elements from the human cytokeratin 18 gene (KRT18, also known as K18). KRT18 is naturally expressed in a spatial pattern similar to that of CFTR, the gene m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40e6c44b7a6935783527ca11ddb14c2
https://doi.org/10.1006/mthe.2001.0412
https://doi.org/10.1006/mthe.2001.0412
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 5:377-384
Normal clearance of alveolar liquid following birth requires active Na transport; however, the contribution of Na channels, Na-H antiports, and Na-glucose symports is unknown. We demonstrated that intraalveolar instillation of amiloride (n = 6) or th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a533eb743a3dd243f82ccf52826f973
https://doi.org/10.1165/ajrcmb/5.4.377
https://doi.org/10.1165/ajrcmb/5.4.377
Publikováno v:
American Review of Respiratory Disease. 142:1083-1087
We investigated the effect of pentoxifylline (PTX) on the development of pulmonary edema in a model of adult respiratory distress syndrome in rabbits. Lung injury was induced by repeated saline lavages in adult rabbits weighing 2.5 to 3.5 kg. Rabbits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b537094a5f1ebef62011ee1c0842036a
https://doi.org/10.1164/ajrccm/142.5.1083
https://doi.org/10.1164/ajrccm/142.5.1083
Autor:
Rukshana Aslam, Robert P. Jankov, A. Keith Tanswell, Xiaoping Luo, Peter Demin, Cecil R. Pace-Asciak, Vicky Hannam
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 301(2)
Bleomycin has been suggested to incite plasma extravasation and influx of inflammatory cells leading to pulmonary fibrosis. We hypothesized that stable analogs of the 12-lipoxygenase product, hepoxilin, may attenuate these effects. We initially inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c61b4b4e47b4185436328641a3825fb
https://pubmed.ncbi.nlm.nih.gov/11961041
https://pubmed.ncbi.nlm.nih.gov/11961041
Autor:
Daniel J. Gillie, Pierre M. Barker, Christopher Sulowski, Hugh O'Brodovich, Bijan Rafii, Vicky Hannam, Gail Otulakowski, Tony Cheung
To determine if pulmonary oedema fluid (EF) alters ion and fluid transport of distal lung epithelium (DLE), EF was collected from rats in acute heart failure. EF, but not plasma, increased amiloride-insensitive short circuit current (I(sc)) and Na(+)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da5ddba5a1dfac1b86ce292e42f7f1b
Autor:
Hugh O'Brodovich, Vicky Hannam
Publikováno v:
The American review of respiratory disease. 147(5)
Neonatal respiratory distress syndrome (RDS) is characterized by a relative surfactant deficiency and air-space edema. We tested the hypothesis that exogenous surfactant would improve gas exchange in mature surfactant-replete lungs containing large a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d3a283d731988bba59e9d7bc517102
https://pubmed.ncbi.nlm.nih.gov/8484614
https://pubmed.ncbi.nlm.nih.gov/8484614
Autor:
P, Jankov Robert, Xiaoping, Luo, Peter, Demin, Rukshana, Aslam, Vicky, Hannam, Keith, Tanswell A, R, Pace-Asciak Cecil
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; May 2002, Vol. 301 Issue: 2 p435-40, 6p
Autor:
Jonathan Plumb, Gregory P. Downey, Yanxia Wen, A. Keith Tanswell, Brent M. Steer, Rosetta Belcastro, Jim Hu, David R. Koehler, Vicky Hannam, Anna Negus, Xiaoping Luo, Judy Cabacungan
Publikováno v:
Scopus-Elsevier
We hypothesized that constitutive formation of reactive oxygen species by respiratory cells is a barrier to gene transfer when liposome-DNA complexes are used, by contributing to rapid degradation of plasmid DNA. When plasmid DNA is complexed to lipo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f370b270504e08c2d6f8b03f04c02e
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037404381&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0037404381&partnerID=MN8TOARS