CUT Domains Stimulate Pol β Enzymatic Activities to Accelerate Completion of Base Excision Repair

Autor: Ramdzan, Zubaidah M., Vickridge, Elise, Li, Li, Faraco, Camila C.F., Djerir, Billel, Leduy, Lam, Maréchal, Alexandre, Nepveu, Alain

Publikováno v: In Journal of Molecular Biology 19 February 2021 433(4)

The function of BCL11B in base excision repair contributes to its dual role as an oncogene and a haplo-insufficient tumor suppressor gene.

Autor: Vickridge, Elise, Faraco, Camila C F, Lo, Fanny, Rahimian, Hedyeh, Liu, Zi Yang, Tehrani, Payman S, Djerir, Billel, Ramdzan, Zubaidah M, Leduy, Lam, Maréchal, Alexandre, Gingras, Anne-Claude, Nepveu, Alain

Publikováno v: Nucleic Acids Research; 1/11/2024, Vol. 52 Issue 1, p223-242, 20p

The DNA repair function of BCL11A suppresses senescence and promotes continued proliferation of triple-negative breast cancer cells.

Autor: Vickridge, Elise, Faraco, Camila C. F., Tehrani, Payman S., Ramdzan, Zubaidah M., Rahimian, Hedyeh, Leduy, Lam, Gingras, Anne-Claude, Nepveu, Alain

Publikováno v: NAR Cancer; Dec2022, Vol. 4 Issue 4, p1-19, 19p

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Base excision repair accessory factors in senescence avoidance and resistance to treatments.

Autor: Vickridge E; Goodman Cancer Institute, McGill University, 1160 Pine avenue West, Montreal, Québec H3A 1A3, Canada.; These authors contributed equally to this work., Faraco CCF; Goodman Cancer Institute, McGill University, 1160 Pine avenue West, Montreal, Québec H3A 1A3, Canada.; Departments of Biochemistry, McGill University, 1160 Pine avenue West, Montreal, Québec H3A 1A3, Canada.; These authors contributed equally to this work., Nepveu A; Goodman Cancer Institute, McGill University, 1160 Pine avenue West, Montreal, Québec H3A 1A3, Canada.; Departments of Biochemistry, McGill University, 1160 Pine avenue West, Montreal, Québec H3A 1A3, Canada.; Medicine, McGill University, 1160 Pine avenue West, Montreal, Québec H3A 1A3, Canada.; Oncology, McGill University, 1160 Pine avenue West, Montreal, Québec H3A 1A3, Canada.

Publikováno v: Cancer drug resistance (Alhambra, Calif.) [Cancer Drug Resist] 2022 Jun 22; Vol. 5 (3), pp. 703-720. Date of Electronic Publication: 2022 Jun 22 (Print Publication: 2022).