Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vicki Olm"'
Autor:
Lois E. McCarthy, Sanja Ivkovic, Chai Tian, Michelle E. Ehrlich, Vicki Olm, Tracy Gieringer, Alexey Bogush
Publikováno v:
genesis. 42:37-46
To direct Cre-mediated recombination to differentiated medium-size spiny neurons (MSNs) of the striatum, we generated transgenic mice that express Cre recombinase under the regulation of DARPP-32 genomic fragments. In this reported line, recombinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b10de8ce7563367fff9967c1a32fa7
https://doi.org/10.1002/gene.20118
https://doi.org/10.1002/gene.20118
Autor:
Antonella Stroppolo, Barbara Guinea, John Sommer, Roxanne Sheffield, Chai Tian, Vicki Olm, Michelle E. Ehrlich
Publikováno v:
Neuroendocrinology. 79:259-267
Gender differences exist in the development of the nigrostriatal dopamine system, and in the incidence and course of pediatric and adult neuropsychiatric diseases in which this system is implicated. The medium size spiny neuron (MSN) is the major out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4afd1934e9a7724f0a0a4340dfb4b88
https://doi.org/10.1159/000079320
https://doi.org/10.1159/000079320
Autor:
Dennis W. Dickson, Vicki Olm, Jordana L Meyerson, Evelyn Casey, Lit Fui Lau, Yasuji Matsuoka, Wendy Noble, Takayuki Kondo, Karen Duff, Kazuyuki Takata, Kate Gaynor, John LaFrancois, Mark P. Burns, Ralph A. Nixon, Peter Davies, Veeranna, Lili Wang, O. Mary, Michael K. Ahlijanian
Publikováno v:
Neuron. 38:555-565
Tau aggregation is a common feature of neurodegenerative diseases such as Alzheimer's disease, and hyperphosphorylation of tau has been implicated as a fundamental pathogenic mechanism in this process. To examine the impact of cdk5 in tau aggregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5874a5845c3a510ee3ed0e373837d971
https://doi.org/10.1016/s0896-6273(03)00259-9
https://doi.org/10.1016/s0896-6273(03)00259-9
Autor:
Yi Wen, John LaFrancois, Mark P. Burns, Boris Feinstein, Wendy Noble, Karen Duff, Vicki Olm, Lili Wang, Kate Gaynor, Pavan Krishnamurthy, Ratan Bhat, Jada Lewis, Dennis W. Dickson, Farhana Suleman, Cindy Zehr, Jordana L Meyerson, Emmanuel Planel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 102(19)
Neurofibrillary tangles composed of hyperphosphorylated, aggregated tau are a common pathological feature of tauopathies, including Alzheimer's disease. Abnormal phosphorylation of tau by kinases or phosphatases has been proposed as a pathogenic mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25842cdc9062a3d460c811e97b22364b
https://pubmed.ncbi.nlm.nih.gov/15867159
https://pubmed.ncbi.nlm.nih.gov/15867159
Autor:
Vicki Olm, Yasuji Matsuoka, Wendy Noble, Marc Mercken, Paul M. Mathews, John LaFrancois, Kate Gaynor, Karen Duff, Mark P. Burns, Lili Wang
Publikováno v:
Scopus-Elsevier
Epidemiology,in vitro, andin vivostudies strongly implicate a role for cholesterol in the pathogenesis of Alzheimer's disease (AD). We have examined the impact of aberrant intracellular cholesterol transport on the processing of the amyloid precursor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74347d634ce79c23172bdd0dd0a0daea
https://europepmc.org/articles/PMC6741250/
https://europepmc.org/articles/PMC6741250/
Autor:
Evelyn Casey, Wendy Noble, Karen Duff, Vicki Olm, John LaFrancois, Mark P. Burns, Lili Wang, Kate Gaynor
Publikováno v:
Brain research. Molecular brain research. 110(1)
Recent evidence strongly suggests a role for cholesterol and apolipoprotein E in the etiology of Alzheimer’s disease. We have demonstrated the co-localization of cholesterol and apolipoprotein E with β-amyloid immunoreactivity and thioflavin S imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cee12fa917ce3c0ded0cc753a018d7a
https://pubmed.ncbi.nlm.nih.gov/12573540
https://pubmed.ncbi.nlm.nih.gov/12573540
Autor:
Yasuji Matsuoka, Karen Duff, Chiharu Shiratori, Yifan Lu, John LaFrancois, Lili Wang, Kate Gaynor, Evelyn Casey, Mariko Saito, Cynthia A. Lemere, Mitsuo Saito, Vicki Olm
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 23(1)
Plaques containing beta-amyloid (Abeta) peptides are one of the pathological features of Alzheimer's disease, and the reduction of Abeta is considered a primary therapeutic target. Amyloid clearance by anti-Abeta antibodies has been reported after im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f18e6fbe7491f65664447c0638dbde
https://pubmed.ncbi.nlm.nih.gov/12514198
https://pubmed.ncbi.nlm.nih.gov/12514198
Autor:
Vicki Olm, Lorenzo M. Refolo, Karen Duff, Nichole S. Diaz, Tara Thomas-Bryant, Ali Sharma, Suzana Petanceska, Steven DeRosa, Miguel A. Pappolla
Publikováno v:
Journal of molecular neuroscience : MN. 19(1-2)
Disease-modifying therapies are being developed for Alzheimer's disease (AD). These are expected to slow the clinical progression of the disease or delay its onset. Cerebral accumulation of amyloid beta (A beta) peptides is an early and perhaps neces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39ab85e046470d27fd5966b9bdd4e17
https://pubmed.ncbi.nlm.nih.gov/12212773
https://pubmed.ncbi.nlm.nih.gov/12212773
Autor:
Alexey I. Bogush, Lois E. McCarthy, Chai Tian, Vicki Olm, Tracy Gieringer, Sanja Ivkovic, Michelle E. Ehrlich
Publikováno v:
Genesis: The Journal of Genetics & Development; May2005, Vol. 42 Issue 1, p37-46, 10p