Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Vicki L J, Whitehall"'
Autor:
Catherine E. Bond, Cheng Liu, Futoshi Kawamata, Diane M. McKeone, Winnie Fernando, Saara Jamieson, Sally-Ann Pearson, Alexandra Kane, Susan L. Woods, Tamsin R. M. Lannagan, Roshini Somashekar, Young Lee, Troy Dumenil, Gunter Hartel, Kevin J. Spring, Jennifer Borowsky, Lochlan Fennell, Mark Bettington, Jason Lee, Daniel L. Worthley, Barbara A. Leggett, Vicki L. J. Whitehall
Publikováno v:
Epigenetics, Vol 13, Iss 1, Pp 40-48 (2018)
Colorectal cancer is a major cause of cancer death and approximately 20% arises within serrated polyps, which are under-recognized and poorly understood. Human serrated colorectal polyps frequently exhibit both oncogenic BRAF mutation and widespread
Externí odkaz:
https://doaj.org/article/a0eb35f1f5c1498b9b8dd60644c1c526
Autor:
Ian Y. Luk, Laura J. Jenkins, Kael L. Schoffer, Irvin Ng, Janson W. T. Tse, Dmitri Mouradov, Stanislaw Kaczmarczyk, Rebecca Nightingale, Allan D. Burrows, Robin L. Anderson, Diego Arango, Higinio Dopeso, Larry Croft, Mark F. Richardson, Oliver M. Sieber, Yang Liao, Jennifer K. Mooi, Natalia Vukelic, Camilla M. Reehorst, Shoukat Afshar-Sterle, Vicki L. J. Whitehall, Lochlan Fennell, Helen E. Abud, Niall C. Tebbutt, Wayne A. Phillips, David S. Williams, Wei Shi, Lisa A. Mielke, Matthias Ernst, Amardeep S. Dhillon, Nicholas J. Clemons, John M. Mariadason
Publikováno v:
Scientia
Epigenetics; Tumour-suppressor proteins Epigenética; Proteínas supresoras de tumores Epigenètica; Proteïnes supresores de tumors Colorectal cancers (CRCs) often display histological features indicative of aberrant differentiation but the molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1771def1a2b343893e5c103bb2bd76
Publikováno v:
Gastroenterology Research and Practice, Vol 2018 (2018)
The BRAF oncogene is an integral component of the MAP kinase pathway, and an activating V600E mutation occurs in 15% of sporadic colorectal cancer. This is an early event in serrated pathway tumourigenesis, and the BRAF V600E has been commonly associ
Externí odkaz:
https://doaj.org/article/0921c89e46c942e680bee526d32d18fd
Autor:
Barbara A. Leggett, Vicki L. J. Whitehall, Lochlan Fennell, Diane McKeone, Graeme P. Young, Catherine Bond, Alexandra M. Kane, Cheng Liu, Pamela M. Pollock
Publikováno v:
Br J Cancer
BACKGROUND: Aspirin reduces the incidence of conventional adenomas driven by APC mutation and thus colorectal cancer. The effect of aspirin on the ~20% of colorectal cancers arising via BRAF mutation is yet to be established. METHODS: Braf(V637E/+);V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bfb4c0a46ad6ae41e4b578f73d41db6
https://doi.org/10.1038/s41416-021-01339-4
https://doi.org/10.1038/s41416-021-01339-4
Publikováno v:
Cancers. 15:2375
Colorectal cancer is one of the world’s most prevalent and lethal cancers. Mutations of the KRAS gene occur in ~40% of metastatic colorectal cancers. While this cohort has historically been difficult to manage, the last few years have shown exponen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::824e1fe166e4bbffebd38feb4dead8f7
https://doi.org/10.3390/cancers15082375
https://doi.org/10.3390/cancers15082375
Autor:
Charles S. Fuchs, Carino Gurjao, Andrew T. Chan, Tabitha A. Harrison, Kenji Fujiyoshi, Susan Bullman, Tomotaka Ugai, Mingyang Song, Reiko Nishihara, Kana Wu, Tsuyoshi Hamada, Kristen Felt, Jochen K. Lennerz, Mai Chan Lau, Jennifer Borowsky, Annacarolina da Silva, Kimmie Ng, Marios Giannakis, Shuji Ogino, Jonathan A. Nowak, Vicki L. J. Whitehall, Melissa Zhao, Edward Giovannucci, Sara A. Väyrynen, Xuehong Zhang, Ian Brown, Mark Bettington, Tyler S. Twombly, Koichiro Haruki, Jeffrey A. Meyerhardt, Kosuke Mima, Neal I. Walker, Ulrike Peters, Juha P. Väyrynen, Wendy S. Garrett, Andressa Dias Costa, Barbara A. Leggett, Amanda I. Phipps, Curtis Huttenhower, Gordon J. Freeman, Kota Arima
Publikováno v:
Clinical Cancer Research. 27:2816-2826
Purpose: While evidence indicates that Fusobacterium nucleatum (F. nucleatum) may promote colorectal carcinogenesis through its suppressive effect on T-cell–mediated antitumor immunity, the specific T-cell subsets involved remain uncertain. Experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60cea2077d41ff9fccae2e08b6e6453e
https://doi.org/10.1158/1078-0432.ccr-20-4009
https://doi.org/10.1158/1078-0432.ccr-20-4009
Autor:
Craig A. Bell, Alexandra M. Kane, Kristofer J. Thurecht, Dewan Taslima Akhter, Barbara A. Leggett, Cheng Liu, Diane McKeone, Vicki L. J. Whitehall
Publikováno v:
Digestive Diseases and Sciences. 66:4326-4332
Colorectal cancer is a leading cause of cancer-related death worldwide and approximately 20% of cases can be attributed to a mutation in the BRAF oncogene. Curcumin is a promising chemopreventive agent with various anti-cancer benefits. Although curc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8e072c2cf4c4119a4b8840eff7d88b8
https://doi.org/10.1007/s10620-020-06752-y
https://doi.org/10.1007/s10620-020-06752-y
Autor:
Anita Pelecanos, Melissa Eastgate, David Wyld, Vicki L. J. Whitehall, Stephanie Collins, Anna Kuchel, Satomi Okano, Matthew Burge, Elizabeth Ahern
Publikováno v:
Asia-Pacific Journal of Clinical Oncology. 17:84-93
Colorectal cancer (CRC) is the third most common cancer in Australia, and survival after diagnosis of metastatic disease is improving. Our aim was to assess trends in epidemiology, treatment, molecular testing and survival in patients with metastatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9f6c26a6fe834af89caa63bdc33a05
https://doi.org/10.1111/ajco.13420
https://doi.org/10.1111/ajco.13420
Autor:
Alison Griffin, Simon Puttick, Paul Thomas, T. Cuda, Vicki L. J. Whitehall, Jennifer Borowsky, Elizabeth Ahern, Cheng Liu, Andrew D. Riddell, David Wyld, John D. Hooper, Nicholas Lyons, Matthew Burge, David A. Clark, Stephen E. Rose, Andrew R. L. Stevenson
Publikováno v:
Journal of Nuclear Medicine. 61:1576-1579
At diagnosis, 22% of colorectal cancer (CRC) patients have metastases, and 50% later develop metastasis. Peptide receptor radionuclide therapy (PRRT), such as 177Lu-PSMA-617, is used to treat metastatic prostate cancer. 177Lu-PSMA-617 targets prostat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f9a38b93caf34cdded76bbac33ada6c
https://doi.org/10.2967/jnumed.119.233312
https://doi.org/10.2967/jnumed.119.233312
Autor:
Cheng Liu, Ann-Marie Patch, Lambros T. Koufariotis, Vicki L. J. Whitehall, Jennifer Borowsky, Stephen H. Kazakoff, John V. Pearson, Catherine Bond, Nicola Waddell, Barbara A. Leggett, Diane McKeone, Lochlan Fennell, Alexandra M. Kane
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 2, Pp 120-128 (2020)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
The serrated neoplasia pathway gives rise to a distinct subgroup of colorectal cancers distinguished by the presence of mutant BRAFV600E and the CpG Island Methylator Phenotype (CIMP). BRAF mutant CRC are commonly associated with microsatellite insta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260bfe1ede9704d895b5f687e5f51c6b
https://doi.org/10.1016/j.neo.2019.12.002
https://doi.org/10.1016/j.neo.2019.12.002